Transcription factor

A0A075B7G4 - ZNF595

Zinc finger protein 595

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 616 aa

82 Generated PWM 24 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)72

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	68.2% identity		Open · Scan
M07586_2.00	NN 70-40%	CisBP	GGGACCCGGGTGGGGGCGTCCCCC	65.5% identity		Open · Scan
M07715_2.00	NN 70-40%	CisBP	CCGCCGCCGCCGTGG	63.3% identity		Open · Scan
M08295_2.00	NN 70-40%	CisBP	CTGCTGGAATCTCCA	63.1% identity		Open · Scan
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	62.3% identity		Open · Scan
M07575_2.00	NN 70-40%	CisBP	TCTCCAAGGCGGCCAGCA	62.1% identity		Open · Scan
M07714_2.00	NN 70-40%	CisBP	AGCCCATTGGGGCCTATGCCC	61.5% identity		Open · Scan
M07775_2.00	NN 70-40%	CisBP	GCCGAAACCCGGG	60.6% identity		Open · Scan
M04611_2.00	NN 70-40%	CisBP	CTTTCGGACAC	60.3% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	60.0% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	60.0% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	60.0% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	60.0% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	60.0% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	60.0% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	60.0% identity		Open · Scan
M07687_2.00	NN 70-40%	CisBP	ACAAATAAGGTTCTTGTGCCCCCTGCT	60.0% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	59.7% identity		Open · Scan
M08381_2.00	NN 70-40%	CisBP	ACATTTTGTCCTCCTAGTCCT	59.7% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	59.2% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	58.9% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	58.8% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	58.8% identity		Open · Scan
M08921_2.00	NN 70-40%	CisBP	CCTCATTCTTCTTGGACATG	58.7% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	58.6% identity		Open · Scan
M07565_2.00	NN 70-40%	CisBP	CCTCTGGGGGCTCGTCCA	58.5% identity		Open · Scan
M07761_2.00	NN 70-40%	CisBP	CTGATTATTCACCCA	58.0% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	57.9% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	57.8% identity		Open · Scan
M08985_2.00	NN 70-40%	CisBP	TGAGGACCTACTGTGTGCC	57.8% identity		Open · Scan
M08934_2.00	NN 70-40%	CisBP	GCTGTACCTGCTTATTAGGC	57.7% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	57.2% identity		Open · Scan
MA1599.1	NN 70-40%	JASPAR	CGGGCCAAGCCCCTAT	56.9% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	56.2% identity		Open · Scan
M04465_2.00	NN 70-40%	CisBP	GTGATTCTTATCTTATCCTT	55.7% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	55.4% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	55.1% identity		Open · Scan
M08395_2.00	NN 70-40%	CisBP	GCTGCCTACTCTTCC	55.1% identity		Open · Scan
M07753_2.00	NN 70-40%	CisBP	TGCATTCCTTGGCTTGTG	54.6% identity		Open · Scan
M07767_2.00	NN 70-40%	CisBP	AAAAACCCCAGA	54.5% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	54.5% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	54.4% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	54.4% identity		Open · Scan
M08949_2.00	NN 70-40%	CisBP	TTCTATTTCTTCTTGTGTCA	54.1% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	53.9% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	53.3% identity		Open · Scan
M08901_2.00	NN 70-40%	CisBP	CCAGTTCACACC	53.1% identity		Open · Scan
M07658_2.00	NN 70-40%	CisBP	CCGCCGCAGCCGCCG	52.9% identity		Open · Scan
M01181_2.00	NN 70-40%	CisBP	GCGCATCCCC	52.7% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	52.6% identity		Open · Scan
M07727_2.00	NN 70-40%	CisBP	CGCCGCCTCCCC	52.3% identity		Open · Scan
MA1596.1	NN 70-40%	JASPAR	GCCTCAGCCTCCCGAG	52.3% identity		Open · Scan
M07666_2.00	NN 70-40%	CisBP	ATCTAGCCCCTGCCTACC	52.2% identity		Open · Scan
M06179_2.00	NN 70-40%	CisBP	TAAGCCTATAGA	51.8% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	51.6% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	51.4% identity		Open · Scan
M04505_2.00	NN 70-40%	CisBP	AGCTTTTCCCACAC	51.3% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	51.3% identity		Open · Scan
M08255_2.00	NN 70-40%	CisBP	CTCTTCCGGT	51.1% identity		Open · Scan
M08908_2.00	NN 70-40%	CisBP	GCTGCTGCTTCTGCTG	51.1% identity		Open · Scan
M07562_2.00	NN 70-40%	CisBP	GAAAAAAAC	50.9% identity		Open · Scan
M04536_2.00	NN 70-40%	CisBP	ACGTAACCCGATACC	50.7% identity		Open · Scan
M08263_2.00	NN 70-40%	CisBP	ATCTCGGCACTTTGGGAGGCCA	50.7% identity		Open · Scan
MA1656.1	NN 70-40%	JASPAR	CCAAGCCCAACCAG	50.7% identity		Open · Scan
M07648_2.00	NN 70-40%	CisBP	GCTTGCAAAAAAAATTTAACTCCCAGCTC	50.6% identity		Open · Scan
M07649_2.00	NN 70-40%	CisBP	CCCCCCCCCCCCTCAGGAATGCC	50.6% identity		Open · Scan
M08330_2.00	NN 70-40%	CisBP	TGGGTGCCGGACTGCTGTTCC	50.4% identity		Open · Scan
M07566_2.00	NN 70-40%	CisBP	TCAAACCATCCTTGC	50.3% identity		Open · Scan
M08314_2.00	NN 70-40%	CisBP	ATTCATCAAGGTCCTCAACAATGG	50.2% identity		Open · Scan
M00786_2.00	NN 70-40%	CisBP	TATATATAT	50.0% identity		Open · Scan
M06169_2.00	NN 70-40%	CisBP	GCCACGCCCAAC	50.0% identity		Open · Scan
M07620_2.00	NN 70-40%	CisBP	TTGGATCTGTGGATTCATGTCTTTCAT	50.0% identity		Open · Scan

ModCRE10

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
TFS_tr_A0A075B7G4_A0A075B7G4_HUMAN:223:499_5v3j_E_1	ModCRE	Homology model	CCCACCCCGGGGGGTGAACCCTCCAG	Region 223-499 · 1 3D model		Open · Scan
TFS_tr_A0A075B7G4_A0A075B7G4_HUMAN:223:499_5v3m_C_1	ModCRE	Homology model	AGAACGCCAAAGGGGGGCGGGCAGGG	Region 223-499 · 1 3D model		Open · Scan
TFS_tr_A0A075B7G4_A0A075B7G4_HUMAN:333:611_5wjq_D_1	ModCRE	Homology model	GGGGCGGCGGGGGGGCCGGGATGCCCCG	Region 333-611 · 1 3D model		Open · Scan
TFS_tr_A0A075B7G4_A0A075B7G4_HUMAN:373:526_2i13_A_1	ModCRE	Homology model	ACCTTTCTTCTCCATATTTGA	Region 373-526 · 1 3D model		Open · Scan
a0a075b7g4.af3.0	ModCRE	AlphaFold3 model	ACCCCCCCCCCCCCCGGCCCCCCCCCCCCA	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a075b7g4.af3.1	ModCRE	AlphaFold3 model	ACCCCCCCCCCCCCCGGCCCCCCCCCCCCA	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a075b7g4.af3.2	ModCRE	AlphaFold3 model	AGCTTAGTACTCTCTAGTCGAGCTCTCCTG	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a075b7g4.af3.3	ModCRE	AlphaFold3 model	GGGGGGGGGGGGGACAGGGTGTGGGGGGGG	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a075b7g4.af3.4	ModCRE	AlphaFold3 model	AGCTAACTACTCTCTACTGTAGCAGTAAGT	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a075b7g4.af3.5	ModCRE	AlphaFold3 model	CCCCCCCCCCCCCCTGCCCTCCCCCCCCCA	AlphaFold3 model · ModCRE PWM		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 616 aa

166-611

Region 166-611 4 PWM

Residues

446 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

6 active PDBs · 6 summary rows

Templates

1LLM, 2I13, 5V3J, 5V3M, 5WJQ, 7W1M

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

24 active PDB models 6 summary rows

Region 166-6116 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_tr_A0A075B7G4_A0A075B7G4_HUMAN:166:217_1llm_D_1	1llm	166-217	View model · PDB
Predicted = Low	TFS_tr_A0A075B7G4_A0A075B7G4_HUMAN:168:466_7w1m_H_1	7w1m	168-466	View model · PDB
Predicted = Low	TFS_tr_A0A075B7G4_A0A075B7G4_HUMAN:223:499_5v3j_E_1	5v3j	223-499	View model · PDB
Predicted = Low	TFS_tr_A0A075B7G4_A0A075B7G4_HUMAN:223:499_5v3m_C_1	5v3m	223-499	View model · PDB
Predicted = Low	TFS_tr_A0A075B7G4_A0A075B7G4_HUMAN:333:611_5wjq_D_1	5wjq	333-611	View model · PDB
Predicted = Low	TFS_tr_A0A075B7G4_A0A075B7G4_HUMAN:373:526_2i13_A_1	2i13	373-526	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
1	5wjq	165:611	333	611	P:D · DNA:A,B	55.6% / 74.2%	99	View · PDB TFS_tr_A0A075B7G4_A0A075B7G4_HUMAN:333:611_5wjq_D_1
4	2i13	165:611	373	526	P:A · DNA:C,D	53.9% / 69.5%	100	View · PDB TFS_tr_A0A075B7G4_A0A075B7G4_HUMAN:373:526_2i13_A_1
2	5v3m	165:611	223	499	P:C · DNA:A,B	53.1% / 72.2%	100	View · PDB TFS_tr_A0A075B7G4_A0A075B7G4_HUMAN:223:499_5v3m_C_1
3	5v3j	165:611	223	499	P:E · DNA:A,B	53.1% / 72.2%	100	View · PDB TFS_tr_A0A075B7G4_A0A075B7G4_HUMAN:223:499_5v3j_E_1
1	1llm	165:611	166,166	217,217	P:C,D · DNA:A,B	46.2% / 63.5%	59,61	View · PDB DIMER_tr_A0A075B7G4_A0A075B7G4_HUMAN:166:217_1llm_D_1
5	7w1m	165:611	168	466	P:H · DNA:F,G	35.4% / 50.3%	92	View · PDB TFS_tr_A0A075B7G4_A0A075B7G4_HUMAN:168:466_7w1m_H_1

Full sequence / unlocalized models18 models

Source	Model	Template	Residues modeled	Actions
Predicted = Low	a0a075b7g4.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a075b7g4.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a075b7g4.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a075b7g4.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a075b7g4.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a075b7g4.af3.5	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a075b7g4_dimer.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a075b7g4_dimer.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a075b7g4_dimer.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a075b7g4_dimer.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a075b7g4_dimer.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a075b7g4_dimer.af3.5	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a075b7g4_monomer.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a075b7g4_monomer.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a075b7g4_monomer.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a075b7g4_monomer.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a075b7g4_monomer.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a075b7g4_monomer.af3.5	-	Full sequence / not localized	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
3-43	PF01352	KRAB box	No overlap with loaded model regions
168-190	PF00096	Zinc finger, C2H2 type	overlaps 166-611
196-218	PF00096	Zinc finger, C2H2 type	overlaps 166-611
224-246	PF00096	Zinc finger, C2H2 type	overlaps 166-611
252-274	PF00096	Zinc finger, C2H2 type	overlaps 166-611
280-302	PF00096	Zinc finger, C2H2 type	overlaps 166-611
308-330	PF00096	Zinc finger, C2H2 type	overlaps 166-611
336-358	PF00096	Zinc finger, C2H2 type	overlaps 166-611
364-386	PF00096	Zinc finger, C2H2 type	overlaps 166-611
392-414	PF00096	Zinc finger, C2H2 type	overlaps 166-611
420-442	PF00096	Zinc finger, C2H2 type	overlaps 166-611
448-470	PF00096	Zinc finger, C2H2 type	overlaps 166-611
476-498	PF00096	Zinc finger, C2H2 type	overlaps 166-611
504-526	PF00096	Zinc finger, C2H2 type	overlaps 166-611
532-554	PF00096	Zinc finger, C2H2 type	overlaps 166-611
560-582	PF00096	Zinc finger, C2H2 type	overlaps 166-611
588-610	PF00096	Zinc finger, C2H2 type	overlaps 166-611