Transcription factor

A0A087WZQ2 - ZNF343

Zinc finger protein 343

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 640 aa

76 Generated PWM 13 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)64

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	62.3% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	62.3% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	62.1% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	60.0% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	59.7% identity		Open · Scan
M07610_2.00	NN 70-40%	CisBP	CCTTCTTCCTCCCCCCTGCCCACC	58.9% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	58.8% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	58.8% identity		Open · Scan
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	58.5% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	57.6% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	57.6% identity		Open · Scan
M07725_2.00	NN 70-40%	CisBP	AAGCACTGTACT	57.4% identity		Open · Scan
M08245_2.00	NN 70-40%	CisBP	TGGTGCCTTATTCCC	56.8% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	56.0% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	55.8% identity		Open · Scan
M08263_2.00	NN 70-40%	CisBP	ATCTCGGCACTTTGGGAGGCCA	54.9% identity		Open · Scan
M07613_2.00	NN 70-40%	CisBP	TCACTCAGTCATTCA	54.7% identity		Open · Scan
M07579_2.00	NN 70-40%	CisBP	CATCTCCAGGA	54.6% identity		Open · Scan
M08887_2.00	NN 70-40%	CisBP	CCTCCTCCAGGAAGCCTTCCCTGA	54.6% identity		Open · Scan
M00774_2.00	NN 70-40%	CisBP	TTAGTATACACAAGT	54.4% identity		Open · Scan
M08944_2.00	NN 70-40%	CisBP	TACCATGCTGTTTTGATTAC	54.3% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	54.1% identity		Open · Scan
M07646_2.00	NN 70-40%	CisBP	CTTTTTTTT	54.0% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	53.9% identity		Open · Scan
M04653_2.00	NN 70-40%	CisBP	GGTACGGTTGTCCATGTTGCAA	53.9% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	53.1% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	52.4% identity		Open · Scan
M08292_2.00	NN 70-40%	CisBP	TGTATTCCTTGTCATGTGTGG	52.3% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	52.3% identity		Open · Scan
M07605_2.00	NN 70-40%	CisBP	TATTTTTTTTTATTTTTTTTTTTTTTTTTT	52.2% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	52.1% identity		Open · Scan
M07689_2.00	NN 70-40%	CisBP	ACCCAGGCTCCTTCCATCTTGTGGCTC	51.9% identity		Open · Scan
M08291_2.00	NN 70-40%	CisBP	AATCCAGCCCTAGACTCTCCC	51.9% identity		Open · Scan
MA1587.1	NN 70-40%	JASPAR	CCTCGACCTCCTGA	51.8% identity		Open · Scan
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	51.7% identity		Open · Scan
M07683_2.00	NN 70-40%	CisBP	GTGGGAAAGCCT	51.7% identity		Open · Scan
M08274_2.00	NN 70-40%	CisBP	TTACTTGCAGCCCAACGCATTCCTAAC	51.7% identity		Open · Scan
MA1601.1	NN 70-40%	JASPAR	ATGTGGGAAA	51.7% identity		Open · Scan
M03671_2.00	NN 70-40%	CisBP	ATTACCATACAAGTGCAC	51.6% identity		Open · Scan
M07700_2.00	NN 70-40%	CisBP	ATGTTGTGAGGAAGCCCA	51.6% identity		Open · Scan
M08314_2.00	NN 70-40%	CisBP	ATTCATCAAGGTCCTCAACAATGG	51.6% identity		Open · Scan
M08399_2.00	NN 70-40%	CisBP	TACTCTGGGGCCACATGACTC	51.6% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	51.3% identity		Open · Scan
MA1463.1	NN 70-40%	JASPAR	TCTAATTAAA	51.3% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	51.2% identity		Open · Scan
M07649_2.00	NN 70-40%	CisBP	CCCCCCCCCCCCTCAGGAATGCC	51.2% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	51.2% identity		Open · Scan
M07666_2.00	NN 70-40%	CisBP	ATCTAGCCCCTGCCTACC	51.1% identity		Open · Scan
M04505_2.00	NN 70-40%	CisBP	AGCTTTTCCCACAC	51.0% identity		Open · Scan
M07593_2.00	NN 70-40%	CisBP	AGATGAAGTCACCCCTCTTAC	50.9% identity		Open · Scan
M08347_2.00	NN 70-40%	CisBP	GCCCTGGGCAGC	50.8% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	50.7% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	50.7% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	50.6% identity		Open · Scan
M00142_2.00	NN 70-40%	CisBP	GTGCTCCT	50.5% identity		Open · Scan
M07747_2.00	NN 70-40%	CisBP	TGGTCTATAAAGGGCCTGGTT	50.4% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	50.1% identity		Open · Scan
M07600_2.00	NN 70-40%	CisBP	GCATTAGC	50.1% identity		Open · Scan
M07662_2.00	NN 70-40%	CisBP	CCTGTGTCCTCCCTGGTCCCC	50.1% identity		Open · Scan
MA1589.1	NN 70-40%	JASPAR	TAGGAGTGGAATTGCTGGGTC	50.1% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	50.0% identity		Open · Scan
M04590_2.00	NN 70-40%	CisBP	TGCGCTAACCATTGC	50.0% identity		Open · Scan
M04611_2.00	NN 70-40%	CisBP	CTTTCGGACAC	50.0% identity		Open · Scan
M07588_2.00	NN 70-40%	CisBP	TCCTTCCCTCTTTCC	50.0% identity		Open · Scan

ModCRE12

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
DIMER_tr_A0A087WZQ2_A0A087WZQ2_HUMAN:392:443_1llm_D_1	ModCRE	Homology model	CCCGCCGGCGTG	Region 392-443 · 1 3D model		Open · Scan
TFS_tr_A0A087WZQ2_A0A087WZQ2_HUMAN:337:613_5v3j_E_1	ModCRE	Homology model	GGCCGGGGGGGGGGCAGGGGGCTTGT	Region 337-613 · 1 3D model		Open · Scan
TFS_tr_A0A087WZQ2_A0A087WZQ2_HUMAN:337:613_5v3m_C_1	ModCRE	Homology model	TGGGGGGGGGGGGGGCGCCCCGGGCG	Region 337-613 · 1 3D model		Open · Scan
TFS_tr_A0A087WZQ2_A0A087WZQ2_HUMAN:363:640_5wjq_D_1	ModCRE	Homology model	CCGGGGGGGGGGGGGCCGGGCTCGTGGG	Region 363-640 · 1 3D model		Open · Scan
TFS_tr_A0A087WZQ2_A0A087WZQ2_HUMAN:375:528_2i13_A_1	ModCRE	Homology model	ACGAAGCTGTAGCCGCAGTTT	Region 375-528 · 1 3D model		Open · Scan
TFS_tr_A0A087WZQ2_A0A087WZQ2_HUMAN:531:640_5ei9_E_1	ModCRE	Homology model	CCGGAGGGGGGGGGGCC	Region 531-640 · 1 3D model		Open · Scan
a0a087wzq2.af3.0	ModCRE	AlphaFold3 model	ACCCGCCCCCACTCTCCCCAGCCCCCCCCC	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a087wzq2.af3.1	ModCRE	AlphaFold3 model	ACCCCCCCGCCCCCCCCCCAGCCCTCCCCC	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a087wzq2.af3.2	ModCRE	AlphaFold3 model	CGGGGAGTGGGGGGGGGGGAGAGGGCGGGC	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a087wzq2.af3.3	ModCRE	AlphaFold3 model	ACCCGCCCCCACTCTCCCCAGCCCTCCCCC	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a087wzq2.af3.4	ModCRE	AlphaFold3 model	GGGGGAGGGGGGGGGGGTGAGAGGGCCGGC	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a087wzq2.af3.5	ModCRE	AlphaFold3 model	CCCGGCCCGGACCCTCTCCACCCCCCCCCC	AlphaFold3 model · ModCRE PWM		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 640 aa

337-640

Region 337-640 6 PWM

Residues

304 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

7 active PDBs · 6 summary rows

Templates

1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ, 7W1M

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

13 active PDB models 6 summary rows

Region 337-6407 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_tr_A0A087WZQ2_A0A087WZQ2_HUMAN:392:443_1llm_D_1	1llm	392-443	View model · PDB
Predicted = Low	TFS_tr_A0A087WZQ2_A0A087WZQ2_HUMAN:337:613_5v3j_E_1	5v3j	337-613	View model · PDB
Predicted = Low	TFS_tr_A0A087WZQ2_A0A087WZQ2_HUMAN:337:613_5v3m_C_1	5v3m	337-613	View model · PDB
Predicted = Low	TFS_tr_A0A087WZQ2_A0A087WZQ2_HUMAN:338:636_7w1m_H_1	7w1m	338-636	View model · PDB
Predicted = Low	TFS_tr_A0A087WZQ2_A0A087WZQ2_HUMAN:363:640_5wjq_D_1	5wjq	363-640	View model · PDB
Predicted = Low	TFS_tr_A0A087WZQ2_A0A087WZQ2_HUMAN:375:528_2i13_A_1	2i13	375-528	View model · PDB
Predicted = Low	TFS_tr_A0A087WZQ2_A0A087WZQ2_HUMAN:531:640_5ei9_E_1	5ei9	531-640	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
4	2i13	306:640	375	528	P:A · DNA:C,D	58.4% / 68.2%	100	View · PDB TFS_tr_A0A087WZQ2_A0A087WZQ2_HUMAN:375:528_2i13_A_1
1	5wjq	306:640	363	640	P:D · DNA:A,B	47.5% / 66.2%	98	View · PDB TFS_tr_A0A087WZQ2_A0A087WZQ2_HUMAN:363:640_5wjq_D_1
2	5v3m	306:640	337	613	P:C · DNA:A,B	47.3% / 65.3%	100	View · PDB TFS_tr_A0A087WZQ2_A0A087WZQ2_HUMAN:337:613_5v3m_C_1
3	5v3j	306:640	337	613	P:E · DNA:A,B	47.3% / 65.3%	100	View · PDB TFS_tr_A0A087WZQ2_A0A087WZQ2_HUMAN:337:613_5v3j_E_1
1	1llm	306:640	392,392	443,443	P:C,D · DNA:A,B	42.3% / 53.8%	59,61	View · PDB DIMER_tr_A0A087WZQ2_A0A087WZQ2_HUMAN:392:443_1llm_D_1
5	7w1m	306:640	338	636	P:H · DNA:F,G	34.7% / 54.2%	92	View · PDB TFS_tr_A0A087WZQ2_A0A087WZQ2_HUMAN:338:636_7w1m_H_1

Full sequence / unlocalized models6 models

Source	Model	Template	Residues modeled	Actions
Predicted = Low	a0a087wzq2.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087wzq2.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087wzq2.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087wzq2.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087wzq2.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087wzq2.af3.5	-	Full sequence / not localized	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
61-102	PF01352	KRAB box	No overlap with loaded model regions
149-170	PF21225	C2H2-type zinc finger	No overlap with loaded model regions
310-332	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
338-360	PF00096	Zinc finger, C2H2 type	overlaps 337-640
394-416	PF00096	Zinc finger, C2H2 type	overlaps 337-640
422-444	PF00096	Zinc finger, C2H2 type	overlaps 337-640
450-472	PF00096	Zinc finger, C2H2 type	overlaps 337-640
478-500	PF00096	Zinc finger, C2H2 type	overlaps 337-640
506-528	PF00096	Zinc finger, C2H2 type	overlaps 337-640
534-556	PF00096	Zinc finger, C2H2 type	overlaps 337-640
562-584	PF00096	Zinc finger, C2H2 type	overlaps 337-640
590-612	PF00096	Zinc finger, C2H2 type	overlaps 337-640
618-640	PF00096	Zinc finger, C2H2 type	overlaps 337-640