Transcription factor

A0A087X0M6 - ZNF850

Zinc finger protein 850

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 1058 aa

101 Generated PWM 24 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)89

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	69.4% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	67.0% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	67.0% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	67.0% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	66.3% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	65.8% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	65.8% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	65.8% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	64.7% identity		Open · Scan
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	64.7% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	64.7% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	64.0% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	63.5% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	62.7% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	62.2% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	62.0% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	61.1% identity		Open · Scan
M08944_2.00	NN 70-40%	CisBP	TACCATGCTGTTTTGATTAC	61.0% identity		Open · Scan
M04465_2.00	NN 70-40%	CisBP	GTGATTCTTATCTTATCCTT	60.7% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	60.3% identity		Open · Scan
M07610_2.00	NN 70-40%	CisBP	CCTTCTTCCTCCCCCCTGCCCACC	59.7% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	59.4% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	59.0% identity		Open · Scan
M07590_2.00	NN 70-40%	CisBP	TTTTTTTCTTTTATTTTTTTTTTTTTTTTTTTT	58.8% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	58.6% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	58.4% identity		Open · Scan
MA1587.1	NN 70-40%	JASPAR	CCTCGACCTCCTGA	58.4% identity		Open · Scan
M07649_2.00	NN 70-40%	CisBP	CCCCCCCCCCCCTCAGGAATGCC	58.3% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	58.1% identity		Open · Scan
M08934_2.00	NN 70-40%	CisBP	GCTGTACCTGCTTATTAGGC	58.1% identity		Open · Scan
M07620_2.00	NN 70-40%	CisBP	TTGGATCTGTGGATTCATGTCTTTCAT	58.0% identity		Open · Scan
M07693_2.00	NN 70-40%	CisBP	CTCCTGTGTGTGCCTTGGCTG	57.8% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	57.8% identity		Open · Scan
M08985_2.00	NN 70-40%	CisBP	TGAGGACCTACTGTGTGCC	57.5% identity		Open · Scan
M08901_2.00	NN 70-40%	CisBP	CCAGTTCACACC	56.8% identity		Open · Scan
MA1154.1	NN 70-40%	JASPAR	CTTTCCCACAACACGAC	56.1% identity		Open · Scan
M07658_2.00	NN 70-40%	CisBP	CCGCCGCAGCCGCCG	56.0% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	56.0% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	56.0% identity		Open · Scan
M08395_2.00	NN 70-40%	CisBP	GCTGCCTACTCTTCC	55.9% identity		Open · Scan
M00786_2.00	NN 70-40%	CisBP	TATATATAT	55.7% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	55.7% identity		Open · Scan
MA1656.1	NN 70-40%	JASPAR	CCAAGCCCAACCAG	55.7% identity		Open · Scan
MA1599.1	NN 70-40%	JASPAR	CGGGCCAAGCCCCTAT	55.5% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	55.3% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	55.2% identity		Open · Scan
M04611_2.00	NN 70-40%	CisBP	CTTTCGGACAC	55.1% identity		Open · Scan
M08859_2.00	NN 70-40%	CisBP	CATTTTTTCCTCCTAGGCCT	54.8% identity		Open · Scan
M04536_2.00	NN 70-40%	CisBP	ACGTAACCCGATACC	54.6% identity		Open · Scan
M05847_2.00	NN 70-40%	CisBP	AGACCTACTATGC	54.6% identity		Open · Scan
MA1585.1	NN 70-40%	JASPAR	ATAGTAGGTG	54.6% identity		Open · Scan
M07648_2.00	NN 70-40%	CisBP	GCTTGCAAAAAAAATTTAACTCCCAGCTC	54.5% identity		Open · Scan
M08330_2.00	NN 70-40%	CisBP	TGGGTGCCGGACTGCTGTTCC	53.8% identity		Open · Scan
M07684_2.00	NN 70-40%	CisBP	CCTGTTCTTGACTTT	53.5% identity		Open · Scan
M07566_2.00	NN 70-40%	CisBP	TCAAACCATCCTTGC	53.0% identity		Open · Scan
M07727_2.00	NN 70-40%	CisBP	CGCCGCCTCCCC	53.0% identity		Open · Scan
MA1596.1	NN 70-40%	JASPAR	GCCTCAGCCTCCCGAG	53.0% identity		Open · Scan
M07562_2.00	NN 70-40%	CisBP	GAAAAAAAC	52.8% identity		Open · Scan
M01440_2.00	NN 70-40%	CisBP	TACGCCAC	52.7% identity		Open · Scan
M08399_2.00	NN 70-40%	CisBP	TACTCTGGGGCCACATGACTC	52.7% identity		Open · Scan
M07678_2.00	NN 70-40%	CisBP	CCCGCCCCCTCCTCCCCCTTCCCACCC	52.6% identity		Open · Scan
M07582_2.00	NN 70-40%	CisBP	TCCCTG	52.5% identity		Open · Scan
M08314_2.00	NN 70-40%	CisBP	ATTCATCAAGGTCCTCAACAATGG	52.4% identity		Open · Scan
M07600_2.00	NN 70-40%	CisBP	GCATTAGC	52.3% identity		Open · Scan
M04505_2.00	NN 70-40%	CisBP	AGCTTTTCCCACAC	52.0% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	51.9% identity		Open · Scan
M07662_2.00	NN 70-40%	CisBP	CCTGTGTCCTCCCTGGTCCCC	51.9% identity		Open · Scan
M07700_2.00	NN 70-40%	CisBP	ATGTTGTGAGGAAGCCCA	51.5% identity		Open · Scan
M07777_2.00	NN 70-40%	CisBP	GCCAATTTCCGTGGTGTAAAT	51.5% identity		Open · Scan
M08274_2.00	NN 70-40%	CisBP	TTACTTGCAGCCCAACGCATTCCTAAC	51.4% identity		Open · Scan
M07689_2.00	NN 70-40%	CisBP	ACCCAGGCTCCTTCCATCTTGTGGCTC	51.3% identity		Open · Scan
M07683_2.00	NN 70-40%	CisBP	GTGGGAAAGCCT	51.2% identity		Open · Scan
M08392_2.00	NN 70-40%	CisBP	CTTCACCTGCTGAGG	51.2% identity		Open · Scan
MA1601.1	NN 70-40%	JASPAR	ATGTGGGAAA	51.2% identity		Open · Scan
M08309_2.00	NN 70-40%	CisBP	AAAAACCCCCCTGCAGAGCCCAGCCCT	51.0% identity		Open · Scan
MA1588.1	NN 70-40%	JASPAR	GAATTCTTGGTTGAC	51.0% identity		Open · Scan
M01474_2.00	NN 70-40%	CisBP	CGCCGATCAC	50.9% identity		Open · Scan
M02913_2.00	NN 70-40%	CisBP	TTCGTGGCATTTTTCTA	50.9% identity		Open · Scan
M04590_2.00	NN 70-40%	CisBP	TGCGCTAACCATTGC	50.8% identity		Open · Scan
M08295_2.00	NN 70-40%	CisBP	CTGCTGGAATCTCCA	50.8% identity		Open · Scan
MA0056.1	NN 70-40%	JASPAR	TGGGGA	50.8% identity		Open · Scan
M07654_2.00	NN 70-40%	CisBP	TGCCCCCTGGTGGC	50.7% identity		Open · Scan
M07731_2.00	NN 70-40%	CisBP	TTTCCCAGCAGCAACAGCACCGCCCCCCCC	50.2% identity		Open · Scan
M00764_2.00	NN 70-40%	CisBP	GTCTACAC	50.1% identity		Open · Scan
M08367_2.00	NN 70-40%	CisBP	GGGGTGATGACCACTCTGGCTTCTTAC	50.1% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	50.0% identity		Open · Scan
M07634_2.00	NN 70-40%	CisBP	AAACGTCCACG	50.0% identity		Open · Scan
M07740_2.00	NN 70-40%	CisBP	TCCTGATTCCACACTCAAACATAACTTT	50.0% identity		Open · Scan
M08908_2.00	NN 70-40%	CisBP	GCTGCTGCTTCTGCTG	50.0% identity		Open · Scan

ModCRE12

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
DIMER_tr_A0A087X0M6_A0A087X0M6_HUMAN:919:968_1llm_D_1	ModCRE	Homology model	CCCCGCGCCGGC	Region 919-968 · 1 3D model		Open · Scan
TFS_tr_A0A087X0M6_A0A087X0M6_HUMAN:276:552_5v3j_E_1	ModCRE	Homology model	CTCCCAGTACACCCCGTCCGCACGCG	Region 276-552 · 1 3D model		Open · Scan
TFS_tr_A0A087X0M6_A0A087X0M6_HUMAN:276:552_5v3m_C_1	ModCRE	Homology model	CGCAACCCCCCCCCCCACCCCAGCCC	Region 276-552 · 1 3D model		Open · Scan
TFS_tr_A0A087X0M6_A0A087X0M6_HUMAN:302:580_5wjq_D_1	ModCRE	Homology model	ACCCCCCCGCGCGCCCCGGATTAGCCCC	Region 302-580 · 1 3D model		Open · Scan
TFS_tr_A0A087X0M6_A0A087X0M6_HUMAN:398:551_2i13_A_1	ModCRE	Homology model	AATCAGGCGCTCGCTCTTCAC	Region 398-551 · 1 3D model		Open · Scan
TFS_tr_A0A087X0M6_A0A087X0M6_HUMAN:529:827_7w1m_H_1	ModCRE	Homology model	AAAGCCCCCAAACAGAGGGGGGTCGTCCTGAAAAGGACCTGCA	Region 529-827 · 1 3D model		Open · Scan
a0a087x0m6.af3.0	ModCRE	AlphaFold3 model	ATGGGGGGTAGAAATGGGGGTATGGCAATG	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a087x0m6.af3.1	ModCRE	AlphaFold3 model	CCATTAAGCTCAGCAAAAGGTGCGCGCTTC	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a087x0m6.af3.2	ModCRE	AlphaFold3 model	AAGGGGGGGATGGGGGGGGGGATGCCCAGG	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a087x0m6.af3.3	ModCRE	AlphaFold3 model	CCTTGATATCCAAACAATTTTTTCAATCCC	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a087x0m6.af3.4	ModCRE	AlphaFold3 model	AGGGGGGGTAGAAATGGGGGTATGGCAATG	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a087x0m6.af3.5	ModCRE	AlphaFold3 model	TACAAAAGTACTAGTAGAGTTGGCCTCTGC	AlphaFold3 model · ModCRE PWM		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 1058 aa

276-827

919-968

Region 276-827 5 PWM

Residues

552 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

5 active PDBs · 5 summary rows

Templates

2I13, 5V3J, 5V3M, 5WJQ, 7W1M

Sources

Predicted = Low

Scan this region Show models

Region 919-968 1 PWM

Residues

50 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

1 active PDB · 1 summary row

Templates

1LLM

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

24 active PDB models 6 summary rows

Region 276-8275 models · 5 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	TFS_tr_A0A087X0M6_A0A087X0M6_HUMAN:276:552_5v3j_E_1	5v3j	276-552	View model · PDB
Predicted = Low	TFS_tr_A0A087X0M6_A0A087X0M6_HUMAN:276:552_5v3m_C_1	5v3m	276-552	View model · PDB
Predicted = Low	TFS_tr_A0A087X0M6_A0A087X0M6_HUMAN:302:580_5wjq_D_1	5wjq	302-580	View model · PDB
Predicted = Low	TFS_tr_A0A087X0M6_A0A087X0M6_HUMAN:398:551_2i13_A_1	2i13	398-551	View model · PDB
Predicted = Low	TFS_tr_A0A087X0M6_A0A087X0M6_HUMAN:529:827_7w1m_H_1	7w1m	529-827	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
4	2i13	276:582	398	551	P:A · DNA:C,D	61.0% / 67.5%	100	View · PDB TFS_tr_A0A087X0M6_A0A087X0M6_HUMAN:398:551_2i13_A_1
1	5wjq	276:582	302	580	P:D · DNA:A,B	58.4% / 73.1%	99	View · PDB TFS_tr_A0A087X0M6_A0A087X0M6_HUMAN:302:580_5wjq_D_1
2	5v3m	276:582	276	552	P:C · DNA:A,B	57.0% / 72.2%	100	View · PDB TFS_tr_A0A087X0M6_A0A087X0M6_HUMAN:276:552_5v3m_C_1
3	5v3j	276:582	276	552	P:E · DNA:A,B	57.0% / 72.2%	100	View · PDB TFS_tr_A0A087X0M6_A0A087X0M6_HUMAN:276:552_5v3j_E_1
5	7w1m	276:582	529	827	P:H · DNA:F,G	36.0% / 50.3%	92	View · PDB TFS_tr_A0A087X0M6_A0A087X0M6_HUMAN:529:827_7w1m_H_1

Region 919-9681 model · 1 summary row

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_tr_A0A087X0M6_A0A087X0M6_HUMAN:919:968_1llm_D_1	1llm	919-968	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
1	1llm	276:582	919,919	968,968	P:C,D · DNA:A,B	42.0% / 64.0%	57,58	View · PDB DIMER_tr_A0A087X0M6_A0A087X0M6_HUMAN:919:968_1llm_D_1

Full sequence / unlocalized models18 models

Source	Model	Template	Residues modeled	Actions
Predicted = Low	a0a087x0m6.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087x0m6.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087x0m6.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087x0m6.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087x0m6.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087x0m6.af3.5	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087x0m6_dimer.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087x0m6_dimer.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087x0m6_dimer.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087x0m6_dimer.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087x0m6_dimer.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087x0m6_dimer.af3.5	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087x0m6_monomer.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087x0m6_monomer.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087x0m6_monomer.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087x0m6_monomer.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087x0m6_monomer.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a087x0m6_monomer.af3.5	-	Full sequence / not localized	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
6-47	PF01352	KRAB box	No overlap with loaded model regions
165-187	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
249-271	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
277-299	PF00096	Zinc finger, C2H2 type	overlaps 276-827
305-327	PF00096	Zinc finger, C2H2 type	overlaps 276-827
333-355	PF00096	Zinc finger, C2H2 type	overlaps 276-827
361-383	PF00096	Zinc finger, C2H2 type	overlaps 276-827
389-411	PF00096	Zinc finger, C2H2 type	overlaps 276-827
417-439	PF00096	Zinc finger, C2H2 type	overlaps 276-827
447-467	PF00096	Zinc finger, C2H2 type	overlaps 276-827
473-495	PF00096	Zinc finger, C2H2 type	overlaps 276-827
501-523	PF00096	Zinc finger, C2H2 type	overlaps 276-827
529-551	PF00096	Zinc finger, C2H2 type	overlaps 276-827
557-579	PF00096	Zinc finger, C2H2 type	overlaps 276-827
585-607	PF00096	Zinc finger, C2H2 type	overlaps 276-827
613-635	PF00096	Zinc finger, C2H2 type	overlaps 276-827
641-663	PF00096	Zinc finger, C2H2 type	overlaps 276-827
669-691	PF00096	Zinc finger, C2H2 type	overlaps 276-827
701-719	PF00096	Zinc finger, C2H2 type	overlaps 276-827
725-747	PF00096	Zinc finger, C2H2 type	overlaps 276-827
753-772	PF00096	Zinc finger, C2H2 type	overlaps 276-827
781-800	PF00096	Zinc finger, C2H2 type	overlaps 276-827
809-831	PF00096	Zinc finger, C2H2 type	overlaps 276-827
837-859	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
865-887	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
893-915	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
921-943	PF00096	Zinc finger, C2H2 type	overlaps 919-968
949-971	PF00096	Zinc finger, C2H2 type	overlaps 919-968
977-999	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
1005-1027	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
1033-1055	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions