ModCRE DB

Transcription factor

A0A0A0MQR4 - CIC

Protein capicua homolog

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 1606 aa

8 Generated PWM 12 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)1
MotifPredictionSourceDNA bindingSupportLogoActions
M03975_2.00 NN 70-40% CisBP TAACAATATCATTGTTA 53.2% identity Open · Scan
ModCRE7
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_tr_A0A0A0MQR4_A0A0A0MQR4_HUMAN:198:269_1o4x_B_1 ModCRE Homology model TTGCTTAATAGGGGCA Region 198-269 · 1 3D model Open · Scan
a0a0a0mqr4.af3.0 ModCRE AlphaFold3 model CTAATTCATCAACCTACAATCCGCAC AlphaFold3 model · ModCRE PWM Open · Scan
a0a0a0mqr4.af3.1 ModCRE AlphaFold3 model CTAATTCATCAACCTACAATCCGCAC AlphaFold3 model · ModCRE PWM Open · Scan
a0a0a0mqr4.af3.2 ModCRE AlphaFold3 model GGGGCCTTTCGTAAAAAACTACAGAAATTC AlphaFold3 model · ModCRE PWM Open · Scan
a0a0a0mqr4.af3.3 ModCRE AlphaFold3 model CCTTTTCAGAGAAAAAATATGGTTCTGG AlphaFold3 model · ModCRE PWM Open · Scan
a0a0a0mqr4.af3.4 ModCRE AlphaFold3 model GGGCAAATTGTTTGCAGAAAATG AlphaFold3 model · ModCRE PWM Open · Scan
a0a0a0mqr4.af3.5 ModCRE AlphaFold3 model ACTTTTCAGCAGGCCACAAAGGCGGTTTT AlphaFold3 model · ModCRE PWM Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 1606 aa
198-276

Region 198-276 1 PWM

Residues
79 aa
Domains
PF00505 · HMG (high mobility group) box
3D models
6 active PDBs · 5 summary rows
Templates
1GT0, 1O4X, 2LEF, 6HT5, 6JRP, 7M5W
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
12 active PDB models 5 summary rows
Region 198-2766 models · 5 summary rows
Actions
Predicted = Low TFS_tr_A0A0A0MQR4_A0A0A0MQR4_HUMAN:198:269_1o4x_B_1 1o4x 198-269 View model · PDB
Predicted = Low TFS_tr_A0A0A0MQR4_A0A0A0MQR4_HUMAN:198:269_6ht5_D_1 6ht5 198-269 View model · PDB
Predicted = Low TFS_tr_A0A0A0MQR4_A0A0A0MQR4_HUMAN:198:271_7m5w_A_1 7m5w 198-271 View model · PDB
Predicted = Low TFS_tr_A0A0A0MQR4_A0A0A0MQR4_HUMAN:198:276_1gt0_D_1 1gt0 198-276 View model · PDB
Predicted = Low TFS_tr_A0A0A0MQR4_A0A0A0MQR4_HUMAN:199:267_2lef_A_1 2lef 199-267 View model · PDB
Predicted = Low TFS_tr_A0A0A0MQR4_A0A0A0MQR4_HUMAN:199:272_6jrp_A_1 6jrp 199-272 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 6jrp 194:276 199 272 P:A · DNA:B,C 100.0% / 100.0% 100 View · PDB TFS_tr_A0A0A0MQR4_A0A0A0MQR4_HUMAN:199:272_6jrp_A_1
2 7m5w 194:276 198 271 P:A · DNA:B,C 100.0% / 100.0% 53 View · PDB TFS_tr_A0A0A0MQR4_A0A0A0MQR4_HUMAN:198:271_7m5w_A_1
5 6ht5 194:276 198 269 P:D · DNA:A,B 40.3% / 61.1% 93 View · PDB TFS_tr_A0A0A0MQR4_A0A0A0MQR4_HUMAN:198:269_6ht5_D_1
4 1gt0 194:276 198 276 P:D · DNA:A,B 38.0% / 59.5% 100 View · PDB TFS_tr_A0A0A0MQR4_A0A0A0MQR4_HUMAN:198:276_1gt0_D_1
3 2lef 194:276 199 267 P:A · DNA:B,C 36.2% / 66.7% 80 View · PDB TFS_tr_A0A0A0MQR4_A0A0A0MQR4_HUMAN:199:267_2lef_A_1
Full sequence / unlocalized models6 models
SourceModelTemplateResidues modeledActions
Predicted = Lowa0a0a0mqr4.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mqr4.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mqr4.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mqr4.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mqr4.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mqr4.af3.5-Full sequence / not localizedView model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
201-268PF00505HMG (high mobility group) boxoverlaps 198-276
1463-1517PF25981Protein capicua homolog-like, C-terminal tri-helical domainNo overlap with loaded model regions