ModCRE DB

Transcription factor

A0A0A0MTH2 - ZNF133

Zinc finger protein 133

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 667 aa

66 Generated PWM 24 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)54
MotifPredictionSourceDNA bindingSupportLogoActions
M00944_2.00 NN 70-40% CisBP TCGCTATAA 65.0% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 62.6% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 62.6% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 60.2% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 60.0% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 60.0% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 58.8% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 57.6% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 57.6% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 56.4% identity Open · Scan
M07666_2.00 NN 70-40% CisBP ATCTAGCCCCTGCCTACC 55.8% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 55.7% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 55.2% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 54.7% identity Open · Scan
M07610_2.00 NN 70-40% CisBP CCTTCTTCCTCCCCCCTGCCCACC 54.6% identity Open · Scan
M07662_2.00 NN 70-40% CisBP CCTGTGTCCTCCCTGGTCCCC 54.3% identity Open · Scan
M03671_2.00 NN 70-40% CisBP ATTACCATACAAGTGCAC 54.1% identity Open · Scan
M08887_2.00 NN 70-40% CisBP CCTCCTCCAGGAAGCCTTCCCTGA 53.7% identity Open · Scan
MA1587.1 NN 70-40% JASPAR CCTCGACCTCCTGA 53.5% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 53.3% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 53.3% identity Open · Scan
M00142_2.00 NN 70-40% CisBP GTGCTCCT 53.0% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 52.8% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 52.7% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 52.7% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 52.4% identity Open · Scan
M08252_2.00 NN 70-40% CisBP CCGGCTCCAGCACCC 52.2% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 52.1% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 52.1% identity Open · Scan
M08245_2.00 NN 70-40% CisBP TGGTGCCTTATTCCC 52.1% identity Open · Scan
M07579_2.00 NN 70-40% CisBP CATCTCCAGGA 51.8% identity Open · Scan
M07605_2.00 NN 70-40% CisBP TATTTTTTTTTATTTTTTTTTTTTTTTTTT 51.8% identity Open · Scan
M07700_2.00 NN 70-40% CisBP ATGTTGTGAGGAAGCCCA 51.7% identity Open · Scan
M08267_2.00 NN 70-40% CisBP CAGTTTCATTTTCC 51.5% identity Open · Scan
M07658_2.00 NN 70-40% CisBP CCGCCGCAGCCGCCG 51.4% identity Open · Scan
M07685_2.00 NN 70-40% CisBP CTTTCCAGCCAC 51.4% identity Open · Scan
M08373_2.00 NN 70-40% CisBP CCCCCTGGCTCTTCCTCT 51.4% identity Open · Scan
M04590_2.00 NN 70-40% CisBP TGCGCTAACCATTGC 51.2% identity Open · Scan
M07593_2.00 NN 70-40% CisBP AGATGAAGTCACCCCTCTTAC 51.2% identity Open · Scan
M08283_2.00 NN 70-40% CisBP GACTTTTATTTT 51.0% identity Open · Scan
M08944_2.00 NN 70-40% CisBP TACCATGCTGTTTTGATTAC 51.0% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 50.9% identity Open · Scan
M08935_2.00 NN 70-40% CisBP CCTCCTCCCTCAGACC 50.8% identity Open · Scan
M07581_2.00 NN 70-40% CisBP TCCCCTGTGCTTCTCTCCCCT 50.6% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 50.6% identity Open · Scan
M07649_2.00 NN 70-40% CisBP CCCCCCCCCCCCTCAGGAATGCC 50.5% identity Open · Scan
M04505_2.00 NN 70-40% CisBP AGCTTTTCCCACAC 50.3% identity Open · Scan
M07683_2.00 NN 70-40% CisBP GTGGGAAAGCCT 50.3% identity Open · Scan
M07712_2.00 NN 70-40% CisBP ACATTTTTTTAATCTAAAAAAACATTTACA 50.3% identity Open · Scan
MA1601.1 NN 70-40% JASPAR ATGTGGGAAA 50.3% identity Open · Scan
M07646_2.00 NN 70-40% CisBP CTTTTTTTT 50.2% identity Open · Scan
M07689_2.00 NN 70-40% CisBP ACCCAGGCTCCTTCCATCTTGTGGCTC 50.1% identity Open · Scan
M01456_2.00 NN 70-40% CisBP GTGATCGGCG 50.0% identity Open · Scan
M02913_2.00 NN 70-40% CisBP TTCGTGGCATTTTTCTA 50.0% identity Open · Scan
ModCRE12
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_A0A0A0MTH2_A0A0A0MTH2_HUMAN:421:472_1llm_C_1 ModCRE Homology model GCCCGGCCGCCA Region 421-472 · 1 3D model Open · Scan
TFS_tr_A0A0A0MTH2_A0A0A0MTH2_HUMAN:310:586_5v3j_E_1 ModCRE Homology model GGGCCGGGGGGGACGAGGGGGTGAGT Region 310-586 · 1 3D model Open · Scan
TFS_tr_A0A0A0MTH2_A0A0A0MTH2_HUMAN:310:586_5v3m_C_1 ModCRE Homology model CCGCCCCGGGGGGGGGGGGGGGAGAG Region 310-586 · 1 3D model Open · Scan
TFS_tr_A0A0A0MTH2_A0A0A0MTH2_HUMAN:336:614_5wjq_D_1 ModCRE Homology model GGGGAGCGCGGGGGGCGGGGCGGGGGGG Region 336-614 · 1 3D model Open · Scan
TFS_tr_A0A0A0MTH2_A0A0A0MTH2_HUMAN:376:529_2i13_A_1 ModCRE Homology model ACTGACTATTACTATGCTATT Region 376-529 · 1 3D model Open · Scan
TFS_tr_A0A0A0MTH2_A0A0A0MTH2_HUMAN:448:558_5ei9_E_1 ModCRE Homology model CCCCAGGGGGGGACGGC Region 448-558 · 1 3D model Open · Scan
a0a0a0mth2.af3.0 ModCRE AlphaFold3 model AGGGGGGAGGGGCGGGGGGGAGGGGGGGGG AlphaFold3 model · ModCRE PWM Open · Scan
a0a0a0mth2.af3.1 ModCRE AlphaFold3 model CTACCCTCCCCCCCCCTCCCCCTCCCCCCT AlphaFold3 model · ModCRE PWM Open · Scan
a0a0a0mth2.af3.2 ModCRE AlphaFold3 model AGGGGGGGGGGGCGGGGGGGGGGGGAGGGA AlphaFold3 model · ModCRE PWM Open · Scan
a0a0a0mth2.af3.3 ModCRE AlphaFold3 model AGGGGGGAGGGGCGGGGGGGCGGGGGGGGG AlphaFold3 model · ModCRE PWM Open · Scan
a0a0a0mth2.af3.4 ModCRE AlphaFold3 model TACCACTCCCCCCCCCCCCCCCACCTCCCC AlphaFold3 model · ModCRE PWM Open · Scan
a0a0a0mth2.af3.5 ModCRE AlphaFold3 model AGGGGGAGGGGGCGGGGAGGGGAGAGGAGT AlphaFold3 model · ModCRE PWM Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 667 aa
310-614

Region 310-614 6 PWM

Residues
305 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
24 active PDB models 6 summary rows
Region 310-6146 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_A0A0A0MTH2_A0A0A0MTH2_HUMAN:421:472_1llm_C_1 1llm 421-472 View model · PDB
Predicted = Low TFS_tr_A0A0A0MTH2_A0A0A0MTH2_HUMAN:310:586_5v3j_E_1 5v3j 310-586 View model · PDB
Predicted = Low TFS_tr_A0A0A0MTH2_A0A0A0MTH2_HUMAN:310:586_5v3m_C_1 5v3m 310-586 View model · PDB
Predicted = Low TFS_tr_A0A0A0MTH2_A0A0A0MTH2_HUMAN:336:614_5wjq_D_1 5wjq 336-614 View model · PDB
Predicted = Low TFS_tr_A0A0A0MTH2_A0A0A0MTH2_HUMAN:376:529_2i13_A_1 2i13 376-529 View model · PDB
Predicted = Low TFS_tr_A0A0A0MTH2_A0A0A0MTH2_HUMAN:448:558_5ei9_E_1 5ei9 448-558 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
5 5ei9 235:639 448 558 P:E · DNA:A,B 71.2% / 86.5% 100 View · PDB TFS_tr_A0A0A0MTH2_A0A0A0MTH2_HUMAN:448:558_5ei9_E_1
4 2i13 235:639 376 529 P:A · DNA:C,D 55.8% / 67.5% 100 View · PDB TFS_tr_A0A0A0MTH2_A0A0A0MTH2_HUMAN:376:529_2i13_A_1
1 5wjq 235:639 336 614 P:D · DNA:A,B 48.0% / 64.9% 99 View · PDB TFS_tr_A0A0A0MTH2_A0A0A0MTH2_HUMAN:336:614_5wjq_D_1
2 5v3m 235:639 310 586 P:C · DNA:A,B 47.7% / 63.9% 100 View · PDB TFS_tr_A0A0A0MTH2_A0A0A0MTH2_HUMAN:310:586_5v3m_C_1
3 5v3j 235:639 310 586 P:E · DNA:A,B 47.7% / 63.9% 100 View · PDB TFS_tr_A0A0A0MTH2_A0A0A0MTH2_HUMAN:310:586_5v3j_E_1
1 1llm 235:639 421,421 472,472 P:C,D · DNA:A,B 46.2% / 67.3% 59,61 View · PDB DIMER_tr_A0A0A0MTH2_A0A0A0MTH2_HUMAN:421:472_1llm_C_1
Full sequence / unlocalized models18 models
SourceModelTemplateResidues modeledActions
Predicted = Lowa0a0a0mth2.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mth2.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mth2.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mth2.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mth2.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mth2.af3.5-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mth2_dimer.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mth2_dimer.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mth2_dimer.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mth2_dimer.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mth2_dimer.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mth2_dimer.af3.5-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mth2_monomer.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mth2_monomer.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mth2_monomer.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mth2_monomer.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mth2_monomer.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a0a0mth2_monomer.af3.5-Full sequence / not localizedView model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
229-249PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
255-277PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
284-305PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
311-333PF00096Zinc finger, C2H2 typeoverlaps 310-614
339-361PF00096Zinc finger, C2H2 typeoverlaps 310-614
368-389PF00096Zinc finger, C2H2 typeoverlaps 310-614
395-417PF00096Zinc finger, C2H2 typeoverlaps 310-614
423-445PF00096Zinc finger, C2H2 typeoverlaps 310-614
451-473PF00096Zinc finger, C2H2 typeoverlaps 310-614
480-501PF00096Zinc finger, C2H2 typeoverlaps 310-614
508-529PF00096Zinc finger, C2H2 typeoverlaps 310-614
535-557PF00096Zinc finger, C2H2 typeoverlaps 310-614
563-585PF00096Zinc finger, C2H2 typeoverlaps 310-614
619-640PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions