Transcription factor

A0A0C4DGB4 - ZNF550

Zinc finger protein 550

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 381 aa

112 Generated PWM 27 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)102

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	64.7% identity		Open · Scan
M08274_2.00	NN 70-40%	CisBP	TTACTTGCAGCCCAACGCATTCCTAAC	62.5% identity		Open · Scan
M08371_2.00	NN 70-40%	CisBP	CCAGACTTGTCCTCT	62.1% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	61.9% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	61.9% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	60.7% identity		Open · Scan
MA1587.1	NN 70-40%	JASPAR	CCTCGACCTCCTGA	60.7% identity		Open · Scan
M08395_2.00	NN 70-40%	CisBP	GCTGCCTACTCTTCC	60.6% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	60.0% identity		Open · Scan
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	60.0% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	60.0% identity		Open · Scan
M08255_2.00	NN 70-40%	CisBP	CTCTTCCGGT	59.9% identity		Open · Scan
M07598_2.00	NN 70-40%	CisBP	CTGACAATACCAAGTGTTGAC	59.4% identity		Open · Scan
M04653_2.00	NN 70-40%	CisBP	GGTACGGTTGTCCATGTTGCAA	59.3% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	59.0% identity		Open · Scan
M04615_2.00	NN 70-40%	CisBP	CTCGATCGAAGGGCACAGTCATT	59.0% identity		Open · Scan
M07715_2.00	NN 70-40%	CisBP	CCGCCGCCGCCGTGG	59.0% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	58.8% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	58.7% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	58.6% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	58.5% identity		Open · Scan
M07590_2.00	NN 70-40%	CisBP	TTTTTTTCTTTTATTTTTTTTTTTTTTTTTTTT	58.5% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	58.5% identity		Open · Scan
M07753_2.00	NN 70-40%	CisBP	TGCATTCCTTGGCTTGTG	58.4% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	58.3% identity		Open · Scan
M08381_2.00	NN 70-40%	CisBP	ACATTTTGTCCTCCTAGTCCT	58.3% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	58.1% identity		Open · Scan
M07587_2.00	NN 70-40%	CisBP	CCCCCTCCCCAGTCGAGCCCCCGC	58.1% identity		Open · Scan
M07678_2.00	NN 70-40%	CisBP	CCCGCCCCCTCCTCCCCCTTCCCACCC	58.1% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	58.1% identity		Open · Scan
M08917_2.00	NN 70-40%	CisBP	GCTGAGCCATGTGGGGTGCT	58.1% identity		Open · Scan
M07714_2.00	NN 70-40%	CisBP	AGCCCATTGGGGCCTATGCCC	58.0% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	57.9% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	57.7% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	57.6% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	57.6% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	57.6% identity		Open · Scan
M08252_2.00	NN 70-40%	CisBP	CCGGCTCCAGCACCC	57.2% identity		Open · Scan
M08292_2.00	NN 70-40%	CisBP	TGTATTCCTTGTCATGTGTGG	57.0% identity		Open · Scan
M08914_2.00	NN 70-40%	CisBP	ATTTAGTCCATTTACATTTAATGT	56.8% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	56.7% identity		Open · Scan
M07579_2.00	NN 70-40%	CisBP	CATCTCCAGGA	56.6% identity		Open · Scan
M08263_2.00	NN 70-40%	CisBP	ATCTCGGCACTTTGGGAGGCCA	56.6% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	56.4% identity		Open · Scan
M07588_2.00	NN 70-40%	CisBP	TCCTTCCCTCTTTCC	56.3% identity		Open · Scan
M04611_2.00	NN 70-40%	CisBP	CTTTCGGACAC	56.1% identity		Open · Scan
M07634_2.00	NN 70-40%	CisBP	AAACGTCCACG	56.1% identity		Open · Scan
M08279_2.00	NN 70-40%	CisBP	CCTCCCTCC	56.0% identity		Open · Scan
M07777_2.00	NN 70-40%	CisBP	GCCAATTTCCGTGGTGTAAAT	55.9% identity		Open · Scan
M08392_2.00	NN 70-40%	CisBP	CTTCACCTGCTGAGG	55.9% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	55.8% identity		Open · Scan
M07657_2.00	NN 70-40%	CisBP	CCCCTGCATGTCCCCATTTTT	55.7% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	55.7% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	55.6% identity		Open · Scan
M08985_2.00	NN 70-40%	CisBP	TGAGGACCTACTGTGTGCC	55.6% identity		Open · Scan
M07638_2.00	NN 70-40%	CisBP	TGCAGCTCCCTGCCC	55.4% identity		Open · Scan
M07762_2.00	NN 70-40%	CisBP	GCCGCGCACAGGCTTCTAGCC	55.4% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	55.1% identity		Open · Scan
MA1597.1	NN 70-40%	JASPAR	CCCAGGGAAGCCATTTC	55.1% identity		Open · Scan
M07605_2.00	NN 70-40%	CisBP	TATTTTTTTTTATTTTTTTTTTTTTTTTTT	55.0% identity		Open · Scan
M07754_2.00	NN 70-40%	CisBP	CGCCCCCTCCCT	55.0% identity		Open · Scan
M07761_2.00	NN 70-40%	CisBP	CTGATTATTCACCCA	55.0% identity		Open · Scan
M08245_2.00	NN 70-40%	CisBP	TGGTGCCTTATTCCC	55.0% identity		Open · Scan
M07725_2.00	NN 70-40%	CisBP	AAGCACTGTACT	54.8% identity		Open · Scan
M08347_2.00	NN 70-40%	CisBP	GCCCTGGGCAGC	54.8% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	54.6% identity		Open · Scan
M07660_2.00	NN 70-40%	CisBP	CCGCGCCTACCTGAGGGCGCGGGCCTGGGG	54.6% identity		Open · Scan
M08949_2.00	NN 70-40%	CisBP	TTCTATTTCTTCTTGTGTCA	54.6% identity		Open · Scan
M04465_2.00	NN 70-40%	CisBP	GTGATTCTTATCTTATCCTT	54.2% identity		Open · Scan
M07740_2.00	NN 70-40%	CisBP	TCCTGATTCCACACTCAAACATAACTTT	54.1% identity		Open · Scan
M07747_2.00	NN 70-40%	CisBP	TGGTCTATAAAGGGCCTGGTT	54.1% identity		Open · Scan
M07775_2.00	NN 70-40%	CisBP	GCCGAAACCCGGG	54.1% identity		Open · Scan
M08234_2.00	NN 70-40%	CisBP	GTCAACTTGACTGGGCCA	54.1% identity		Open · Scan
M07723_2.00	NN 70-40%	CisBP	CCGCTGCTCCCTGCT	53.9% identity		Open · Scan
M08335_2.00	NN 70-40%	CisBP	AGTCGTTGTCTG	53.7% identity		Open · Scan
M07701_2.00	NN 70-40%	CisBP	CCTGGGCTAGGCCCTGGC	53.6% identity		Open · Scan
M07566_2.00	NN 70-40%	CisBP	TCAAACCATCCTTGC	53.5% identity		Open · Scan
M08247_2.00	NN 70-40%	CisBP	AAAAATAACAAACGG	53.5% identity		Open · Scan
M08300_2.00	NN 70-40%	CisBP	CTGCCCAATTCAT	53.5% identity		Open · Scan
M08386_2.00	NN 70-40%	CisBP	GCCTTAAAAGCTCAGCAC	53.5% identity		Open · Scan
MA1594.1	NN 70-40%	JASPAR	AGGGGACATCACTACAGATCCCAC	53.5% identity		Open · Scan
M07593_2.00	NN 70-40%	CisBP	AGATGAAGTCACCCCTCTTAC	53.4% identity		Open · Scan
M07601_2.00	NN 70-40%	CisBP	CAGATGCCGGCACCATGCTTC	53.3% identity		Open · Scan
M07712_2.00	NN 70-40%	CisBP	ACATTTTTTTAATCTAAAAAAACATTTACA	53.2% identity		Open · Scan
M01474_2.00	NN 70-40%	CisBP	CGCCGATCAC	53.0% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	53.0% identity		Open · Scan
M07567_2.00	NN 70-40%	CisBP	CCACTCCACTCA	52.6% identity		Open · Scan
M08860_2.00	NN 70-40%	CisBP	TCTTATAAGGGCACTAATCCCATT	52.6% identity		Open · Scan
M07595_2.00	NN 70-40%	CisBP	GCCTGTTCCTCTCCC	52.4% identity		Open · Scan
M07770_2.00	NN 70-40%	CisBP	CTTGGACTT	52.4% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	52.3% identity		Open · Scan
M07659_2.00	NN 70-40%	CisBP	GTCTTCCAAGTAGCTGGTGTT	51.9% identity		Open · Scan
M07731_2.00	NN 70-40%	CisBP	TTTCCCAGCAGCAACAGCACCGCCCCCCCC	51.9% identity		Open · Scan
M04536_2.00	NN 70-40%	CisBP	ACGTAACCCGATACC	51.8% identity		Open · Scan
M07717_2.00	NN 70-40%	CisBP	GGCTCCGCCCCC	51.5% identity		Open · Scan
M08357_2.00	NN 70-40%	CisBP	GAGCCTGCTACTGAGCCTGGG	51.3% identity		Open · Scan
MA0056.1	NN 70-40%	JASPAR	TGGGGA	51.3% identity		Open · Scan
M08901_2.00	NN 70-40%	CisBP	CCAGTTCACACC	51.0% identity		Open · Scan
M07680_2.00	NN 70-40%	CisBP	AACCCCAAC	50.4% identity		Open · Scan
MA1656.1	NN 70-40%	JASPAR	CCAAGCCCAACCAG	50.2% identity		Open · Scan
M07613_2.00	NN 70-40%	CisBP	TCACTCAGTCATTCA	50.1% identity		Open · Scan
M08283_2.00	NN 70-40%	CisBP	GACTTTTATTTT	50.0% identity		Open · Scan

ModCRE10

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
DIMER_tr_A0A0C4DGB4_A0A0C4DGB4_HUMAN:272:323_1llm_D_1	ModCRE	Homology model	ATCCGCGCGCAA	Region 272-323 · 1 3D model		Open · Scan
TFS_tr_A0A0C4DGB4_A0A0C4DGB4_HUMAN:215:381_5und_A_1	ModCRE	Homology model	AACGGCTTGCCGGAACTGGCCTGCT	Region 215-381 · 1 3D model		Open · Scan
TFS_tr_A0A0C4DGB4_A0A0C4DGB4_HUMAN:271:381_5egb_A_1	ModCRE	Homology model	TGGTGAAAAGCAGGAGGT	Region 271-381 · 1 3D model		Open · Scan
TFS_tr_A0A0C4DGB4_A0A0C4DGB4_HUMAN:273:381_5eh2_F_1	ModCRE	Homology model	GGCCAGGGCCGGCGAATCC	Region 273-381 · 1 3D model		Open · Scan
a0a0c4dgb4.af3.0	ModCRE	AlphaFold3 model	GGCCGCCCCTCCCCCTCCCCCCCCCCAGG	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a0c4dgb4.af3.1	ModCRE	AlphaFold3 model	CCGGGGAGGTGGTAGGGGGAGGGCCCCTCA	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a0c4dgb4.af3.2	ModCRE	AlphaFold3 model	GGCCACCCCTCCCCCTCCCCCCCCCCCGG	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a0c4dgb4.af3.3	ModCRE	AlphaFold3 model	CCGGGGAGGGGGGAGGGGGGGAGGCCCCG	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a0c4dgb4.af3.4	ModCRE	AlphaFold3 model	CGCCGTCTCTCCCCCTCCCCCCCCCCGGC	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a0c4dgb4.af3.5	ModCRE	AlphaFold3 model	GGCCGCCCCTCCCCCTCCCCCCCCCCAGG	AlphaFold3 model · ModCRE PWM		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 381 aa

155-381

Region 155-381 4 PWM

Residues

227 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

9 active PDBs · 6 summary rows

Templates

1LLM, 2I13, 5EGB, 5EH2, 5EI9, 5UND, 5V3J, 5V3M, ...

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

27 active PDB models 6 summary rows

Region 155-3819 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_tr_A0A0C4DGB4_A0A0C4DGB4_HUMAN:272:323_1llm_D_1	1llm	272-323	View model · PDB
Predicted = Low	TFS_tr_A0A0C4DGB4_A0A0C4DGB4_HUMAN:155:381_5v3j_E_1	5v3j	155-381	View model · PDB
Predicted = Low	TFS_tr_A0A0C4DGB4_A0A0C4DGB4_HUMAN:155:381_5v3m_C_1	5v3m	155-381	View model · PDB
Predicted = Low	TFS_tr_A0A0C4DGB4_A0A0C4DGB4_HUMAN:155:381_5wjq_D_1	5wjq	155-381	View model · PDB
Predicted = Low	TFS_tr_A0A0C4DGB4_A0A0C4DGB4_HUMAN:215:381_5und_A_1	5und	215-381	View model · PDB
Predicted = Low	TFS_tr_A0A0C4DGB4_A0A0C4DGB4_HUMAN:227:380_2i13_A_1	2i13	227-380	View model · PDB
Predicted = Low	TFS_tr_A0A0C4DGB4_A0A0C4DGB4_HUMAN:271:381_5egb_A_1	5egb	271-381	View model · PDB
Predicted = Low	TFS_tr_A0A0C4DGB4_A0A0C4DGB4_HUMAN:271:381_5ei9_E_1	5ei9	271-381	View model · PDB
Predicted = Low	TFS_tr_A0A0C4DGB4_A0A0C4DGB4_HUMAN:273:381_5eh2_F_1	5eh2	273-381	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
5	5ei9	155:381	271	381	P:E · DNA:A,B	55.9% / 71.2%	100	View · PDB TFS_tr_A0A0C4DGB4_A0A0C4DGB4_HUMAN:271:381_5ei9_E_1
4	2i13	155:381	227	380	P:A · DNA:C,D	53.9% / 64.9%	100	View · PDB TFS_tr_A0A0C4DGB4_A0A0C4DGB4_HUMAN:227:380_2i13_A_1
2	5v3m	155:381	155	381	P:C · DNA:A,B	52.0% / 66.5%	81	View · PDB TFS_tr_A0A0C4DGB4_A0A0C4DGB4_HUMAN:155:381_5v3m_C_1
3	5v3j	155:381	155	381	P:E · DNA:A,B	52.0% / 66.5%	81	View · PDB TFS_tr_A0A0C4DGB4_A0A0C4DGB4_HUMAN:155:381_5v3j_E_1
1	5wjq	155:381	155	381	P:D · DNA:A,B	52.0% / 66.1%	80	View · PDB TFS_tr_A0A0C4DGB4_A0A0C4DGB4_HUMAN:155:381_5wjq_D_1
1	1llm	155:381	272,272	323,323	P:C,D · DNA:A,B	46.2% / 59.6%	59,61	View · PDB DIMER_tr_A0A0C4DGB4_A0A0C4DGB4_HUMAN:272:323_1llm_D_1

Full sequence / unlocalized models18 models

Source	Model	Template	Residues modeled	Actions
Predicted = Low	a0a0c4dgb4.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgb4.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgb4.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgb4.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgb4.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgb4.af3.5	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgb4_dimer.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgb4_dimer.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgb4_dimer.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgb4_dimer.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgb4_dimer.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgb4_dimer.af3.5	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgb4_monomer.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgb4_monomer.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgb4_monomer.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgb4_monomer.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgb4_monomer.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgb4_monomer.af3.5	-	Full sequence / not localized	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
2-43	PF01352	KRAB box	No overlap with loaded model regions
162-184	PF00096	Zinc finger, C2H2 type	overlaps 155-381
190-212	PF00096	Zinc finger, C2H2 type	overlaps 155-381
218-237	PF00096	Zinc finger, C2H2 type	overlaps 155-381
246-268	PF00096	Zinc finger, C2H2 type	overlaps 155-381
274-296	PF00096	Zinc finger, C2H2 type	overlaps 155-381
330-352	PF00096	Zinc finger, C2H2 type	overlaps 155-381
358-380	PF00096	Zinc finger, C2H2 type	overlaps 155-381