Transcription factor

A0A0C4DGP9 - ZNF568

Zinc finger protein 568

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 530 aa

99 Generated PWM 24 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)88

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	69.3% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	67.0% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	65.9% identity		Open · Scan
M07613_2.00	NN 70-40%	CisBP	TCACTCAGTCATTCA	65.8% identity		Open · Scan
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	65.4% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	65.3% identity		Open · Scan
M04653_2.00	NN 70-40%	CisBP	GGTACGGTTGTCCATGTTGCAA	64.0% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	63.6% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	63.5% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	63.1% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	63.0% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	62.8% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	62.5% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	62.5% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	62.3% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	61.4% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	61.3% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	61.1% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	60.2% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	60.2% identity		Open · Scan
M08985_2.00	NN 70-40%	CisBP	TGAGGACCTACTGTGTGCC	60.1% identity		Open · Scan
M04611_2.00	NN 70-40%	CisBP	CTTTCGGACAC	60.0% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	59.5% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	59.5% identity		Open · Scan
M04465_2.00	NN 70-40%	CisBP	GTGATTCTTATCTTATCCTT	59.2% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	59.2% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	58.9% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	57.7% identity		Open · Scan
M07649_2.00	NN 70-40%	CisBP	CCCCCCCCCCCCTCAGGAATGCC	57.7% identity		Open · Scan
M07753_2.00	NN 70-40%	CisBP	TGCATTCCTTGGCTTGTG	57.7% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	57.6% identity		Open · Scan
M00217_2.00	NN 70-40%	CisBP	TTACTCAATAT	57.5% identity		Open · Scan
M07712_2.00	NN 70-40%	CisBP	ACATTTTTTTAATCTAAAAAAACATTTACA	56.9% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	56.7% identity		Open · Scan
M07587_2.00	NN 70-40%	CisBP	CCCCCTCCCCAGTCGAGCCCCCGC	56.6% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	56.5% identity		Open · Scan
M07610_2.00	NN 70-40%	CisBP	CCTTCTTCCTCCCCCCTGCCCACC	56.4% identity		Open · Scan
M07683_2.00	NN 70-40%	CisBP	GTGGGAAAGCCT	56.1% identity		Open · Scan
M08901_2.00	NN 70-40%	CisBP	CCAGTTCACACC	56.1% identity		Open · Scan
MA1601.1	NN 70-40%	JASPAR	ATGTGGGAAA	56.1% identity		Open · Scan
M08395_2.00	NN 70-40%	CisBP	GCTGCCTACTCTTCC	56.0% identity		Open · Scan
M08309_2.00	NN 70-40%	CisBP	AAAAACCCCCCTGCAGAGCCCAGCCCT	55.9% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	55.8% identity		Open · Scan
M07588_2.00	NN 70-40%	CisBP	TCCTTCCCTCTTTCC	55.7% identity		Open · Scan
M07566_2.00	NN 70-40%	CisBP	TCAAACCATCCTTGC	55.3% identity		Open · Scan
M07648_2.00	NN 70-40%	CisBP	GCTTGCAAAAAAAATTTAACTCCCAGCTC	55.2% identity		Open · Scan
M06108_2.00	NN 70-40%	CisBP	ACAACAACAAC	55.1% identity		Open · Scan
M07754_2.00	NN 70-40%	CisBP	CGCCCCCTCCCT	55.1% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	55.0% identity		Open · Scan
M01474_2.00	NN 70-40%	CisBP	CGCCGATCAC	54.9% identity		Open · Scan
M07701_2.00	NN 70-40%	CisBP	CCTGGGCTAGGCCCTGGC	54.9% identity		Open · Scan
M07618_2.00	NN 70-40%	CisBP	CCTTTGGTGCTC	54.8% identity		Open · Scan
M07667_2.00	NN 70-40%	CisBP	CCGCACAGGCCCCCGGGCCCC	54.6% identity		Open · Scan
M00142_2.00	NN 70-40%	CisBP	GTGCTCCT	54.5% identity		Open · Scan
M04536_2.00	NN 70-40%	CisBP	ACGTAACCCGATACC	54.4% identity		Open · Scan
M08335_2.00	NN 70-40%	CisBP	AGTCGTTGTCTG	54.2% identity		Open · Scan
M00609_2.00	NN 70-40%	CisBP	GGAAGCCCTA	54.1% identity		Open · Scan
MA1588.1	NN 70-40%	JASPAR	GAATTCTTGGTTGAC	54.0% identity		Open · Scan
M07605_2.00	NN 70-40%	CisBP	TATTTTTTTTTATTTTTTTTTTTTTTTTTT	53.9% identity		Open · Scan
M07600_2.00	NN 70-40%	CisBP	GCATTAGC	53.8% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	53.6% identity		Open · Scan
MA1154.1	NN 70-40%	JASPAR	CTTTCCCACAACACGAC	53.2% identity		Open · Scan
M00786_2.00	NN 70-40%	CisBP	TATATATAT	53.1% identity		Open · Scan
M07746_2.00	NN 70-40%	CisBP	CAGCTGGCGCCCAACATGGGTCCC	53.1% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	52.8% identity		Open · Scan
M07770_2.00	NN 70-40%	CisBP	CTTGGACTT	52.7% identity		Open · Scan
MA1656.1	NN 70-40%	JASPAR	CCAAGCCCAACCAG	52.7% identity		Open · Scan
M08917_2.00	NN 70-40%	CisBP	GCTGAGCCATGTGGGGTGCT	52.6% identity		Open · Scan
M08255_2.00	NN 70-40%	CisBP	CTCTTCCGGT	52.4% identity		Open · Scan
M08366_2.00	NN 70-40%	CisBP	GTTTGCTGCTTACAA	52.2% identity		Open · Scan
M07662_2.00	NN 70-40%	CisBP	CCTGTGTCCTCCCTGGTCCCC	52.1% identity		Open · Scan
M07562_2.00	NN 70-40%	CisBP	GAAAAAAAC	52.0% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	52.0% identity		Open · Scan
M04590_2.00	NN 70-40%	CisBP	TGCGCTAACCATTGC	51.6% identity		Open · Scan
MA0528.1	NN 70-40%	JASPAR	GGAGGAGGAGGGGGAGGAGGA	51.6% identity		Open · Scan
M07660_2.00	NN 70-40%	CisBP	CCGCGCCTACCTGAGGGCGCGGGCCTGGGG	51.5% identity		Open · Scan
M00764_2.00	NN 70-40%	CisBP	GTCTACAC	51.3% identity		Open · Scan
M08300_2.00	NN 70-40%	CisBP	CTGCCCAATTCAT	51.2% identity		Open · Scan
M08392_2.00	NN 70-40%	CisBP	CTTCACCTGCTGAGG	51.1% identity		Open · Scan
M01456_2.00	NN 70-40%	CisBP	GTGATCGGCG	50.9% identity		Open · Scan
M07684_2.00	NN 70-40%	CisBP	CCTGTTCTTGACTTT	50.7% identity		Open · Scan
M08934_2.00	NN 70-40%	CisBP	GCTGTACCTGCTTATTAGGC	50.6% identity		Open · Scan
M07689_2.00	NN 70-40%	CisBP	ACCCAGGCTCCTTCCATCTTGTGGCTC	50.5% identity		Open · Scan
M01044_2.00	NN 70-40%	CisBP	TCTCTCTTTC	50.3% identity		Open · Scan
M08247_2.00	NN 70-40%	CisBP	AAAAATAACAAACGG	50.2% identity		Open · Scan
M07601_2.00	NN 70-40%	CisBP	CAGATGCCGGCACCATGCTTC	50.1% identity		Open · Scan
M03702_2.00	NN 70-40%	CisBP	GACCCCCCACGACGC	50.0% identity		Open · Scan
M07678_2.00	NN 70-40%	CisBP	CCCGCCCCCTCCTCCCCCTTCCCACCC	50.0% identity		Open · Scan

ModCRE11

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
DIMER_tr_A0A0C4DGP9_A0A0C4DGP9_HUMAN:184:235_1llm_D_1	ModCRE	Homology model	TCCGCGGGCGGG	Region 184-235 · 1 3D model		Open · Scan
TFS_tr_A0A0C4DGP9_A0A0C4DGP9_HUMAN:185:461_5v3j_E_1	ModCRE	Homology model	TCTAGTCCCTTCAGTTGGGGGTCCCG	Region 185-461 · 1 3D model		Open · Scan
TFS_tr_A0A0C4DGP9_A0A0C4DGP9_HUMAN:185:461_5v3m_C_1	ModCRE	Homology model	GGGACCCCGCCCCCGCCCCGCCCCGC	Region 185-461 · 1 3D model		Open · Scan
TFS_tr_A0A0C4DGP9_A0A0C4DGP9_HUMAN:211:489_5wjq_D_1	ModCRE	Homology model	GTGCCCCCCCCCTCCCCCCCCCCCCCCC	Region 211-489 · 1 3D model		Open · Scan
TFS_tr_A0A0C4DGP9_A0A0C4DGP9_HUMAN:363:516_2i13_A_1	ModCRE	Homology model	CTGAGGCAGGTGCCTATAAGT	Region 363-516 · 1 3D model		Open · Scan
a0a0c4dgp9.af3.0	ModCRE	AlphaFold3 model	GCACCAGCTCCTACTTTAACAAATGTAGCG	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a0c4dgp9.af3.1	ModCRE	AlphaFold3 model	CGCTACAGTAGCTAAAGTAGTAGCTGGCGC	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a0c4dgp9.af3.2	ModCRE	AlphaFold3 model	CGCTACGTTTGGAAAAGTAGGAGCTAGCGC	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a0c4dgp9.af3.3	ModCRE	AlphaFold3 model	GGGGGGGGGGGAGAGGGACCGTGGAGGAGA	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a0c4dgp9.af3.4	ModCRE	AlphaFold3 model	GCACCAGCTCCTACTTTAACAAATGTAGCG	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a0c4dgp9.af3.5	ModCRE	AlphaFold3 model	ATCTACCGAGATAGCTCCTAGTTGGCACCT	AlphaFold3 model · ModCRE PWM		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 530 aa

184-516

Region 184-516 5 PWM

Residues

333 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

6 active PDBs · 6 summary rows

Templates

1LLM, 2I13, 5V3J, 5V3M, 5WJQ, 7W1M

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

24 active PDB models 6 summary rows

Region 184-5166 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_tr_A0A0C4DGP9_A0A0C4DGP9_HUMAN:184:235_1llm_D_1	1llm	184-235	View model · PDB
Predicted = Low	TFS_tr_A0A0C4DGP9_A0A0C4DGP9_HUMAN:185:461_5v3j_E_1	5v3j	185-461	View model · PDB
Predicted = Low	TFS_tr_A0A0C4DGP9_A0A0C4DGP9_HUMAN:185:461_5v3m_C_1	5v3m	185-461	View model · PDB
Predicted = Low	TFS_tr_A0A0C4DGP9_A0A0C4DGP9_HUMAN:186:484_7w1m_H_1	7w1m	186-484	View model · PDB
Predicted = Low	TFS_tr_A0A0C4DGP9_A0A0C4DGP9_HUMAN:211:489_5wjq_D_1	5wjq	211-489	View model · PDB
Predicted = Low	TFS_tr_A0A0C4DGP9_A0A0C4DGP9_HUMAN:363:516_2i13_A_1	2i13	363-516	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
4	2i13	183:520	363	516	P:A · DNA:C,D	59.7% / 75.3%	100	View · PDB TFS_tr_A0A0C4DGP9_A0A0C4DGP9_HUMAN:363:516_2i13_A_1
1	5wjq	183:520	211	489	P:D · DNA:A,B	53.8% / 68.8%	99	View · PDB TFS_tr_A0A0C4DGP9_A0A0C4DGP9_HUMAN:211:489_5wjq_D_1
2	5v3m	183:520	185	461	P:C · DNA:A,B	53.8% / 68.2%	100	View · PDB TFS_tr_A0A0C4DGP9_A0A0C4DGP9_HUMAN:185:461_5v3m_C_1
3	5v3j	183:520	185	461	P:E · DNA:A,B	53.8% / 68.2%	100	View · PDB TFS_tr_A0A0C4DGP9_A0A0C4DGP9_HUMAN:185:461_5v3j_E_1
1	1llm	183:520	184,184	235,235	P:C,D · DNA:A,B	44.2% / 65.4%	59,61	View · PDB DIMER_tr_A0A0C4DGP9_A0A0C4DGP9_HUMAN:184:235_1llm_D_1
5	7w1m	183:520	186	484	P:H · DNA:F,G	37.0% / 53.9%	92	View · PDB TFS_tr_A0A0C4DGP9_A0A0C4DGP9_HUMAN:186:484_7w1m_H_1

Full sequence / unlocalized models18 models

Source	Model	Template	Residues modeled	Actions
Predicted = Low	a0a0c4dgp9.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgp9.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgp9.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgp9.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgp9.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgp9.af3.5	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgp9_dimer.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgp9_dimer.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgp9_dimer.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgp9_dimer.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgp9_dimer.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgp9_dimer.af3.5	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgp9_monomer.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgp9_monomer.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgp9_monomer.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgp9_monomer.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgp9_monomer.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a0c4dgp9_monomer.af3.5	-	Full sequence / not localized	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
2-24	PF01352	KRAB box	No overlap with loaded model regions
158-180	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
186-208	PF00096	Zinc finger, C2H2 type	overlaps 184-516
214-236	PF00096	Zinc finger, C2H2 type	overlaps 184-516
242-264	PF00096	Zinc finger, C2H2 type	overlaps 184-516
270-292	PF00096	Zinc finger, C2H2 type	overlaps 184-516
298-320	PF00096	Zinc finger, C2H2 type	overlaps 184-516
326-348	PF00096	Zinc finger, C2H2 type	overlaps 184-516
354-376	PF00096	Zinc finger, C2H2 type	overlaps 184-516
382-404	PF00096	Zinc finger, C2H2 type	overlaps 184-516
410-432	PF00096	Zinc finger, C2H2 type	overlaps 184-516
438-460	PF00096	Zinc finger, C2H2 type	overlaps 184-516
466-488	PF00096	Zinc finger, C2H2 type	overlaps 184-516
494-516	PF00096	Zinc finger, C2H2 type	overlaps 184-516