ModCRE DB

Transcription factor

A0A1B0GW50 - ZEB2

Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (Zinc finger homeobox protein 1b)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 1202 aa

34 Generated PWM 31 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)21
MotifPredictionSourceDNA bindingSupportLogoActions
M07842_2.00 NN 70-40% CisBP CTCACCTG 60.6% identity Open · Scan
M06179_2.00 NN 70-40% CisBP TAAGCCTATAGA 56.8% identity Open · Scan
MA1587.1 NN 70-40% JASPAR CCTCGACCTCCTGA 53.3% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 53.0% identity Open · Scan
M08311_2.00 NN 70-40% CisBP CTGGAACAGAAGGGGCGA 52.2% identity Open · Scan
M07753_2.00 NN 70-40% CisBP TGCATTCCTTGGCTTGTG 52.0% identity Open · Scan
M08860_2.00 NN 70-40% CisBP TCTTATAAGGGCACTAATCCCATT 52.0% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 51.3% identity Open · Scan
M07667_2.00 NN 70-40% CisBP CCGCACAGGCCCCCGGGCCCC 50.7% identity Open · Scan
M08252_2.00 NN 70-40% CisBP CCGGCTCCAGCACCC 50.7% identity Open · Scan
M04475_2.00 NN 70-40% CisBP GATGCACGTACCGTGCCTCA 50.6% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 50.6% identity Open · Scan
M07590_2.00 NN 70-40% CisBP TTTTTTTCTTTTATTTTTTTTTTTTTTTTTTTT 50.6% identity Open · Scan
M08335_2.00 NN 70-40% CisBP AGTCGTTGTCTG 50.6% identity Open · Scan
M08347_2.00 NN 70-40% CisBP GCCCTGGGCAGC 50.6% identity Open · Scan
M01468_2.00 NN 70-40% CisBP TTACCCCTGA 50.0% identity Open · Scan
M07600_2.00 NN 70-40% CisBP GCATTAGC 50.0% identity Open · Scan
M08386_2.00 NN 70-40% CisBP GCCTTAAAAGCTCAGCAC 50.0% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 50.0% identity Open · Scan
MA0038.1 NN 70-40% JASPAR CAAATCACTG 50.0% identity Open · Scan
MA0038.2 NN 70-40% JASPAR CAAATCACTGCA 50.0% identity Open · Scan
ModCRE13
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:659:696_1au7_B_1 ModCRE Homology model TTTTTAACTTCATCGCTTTCAAGA Region 659-696 · 1 3D model Open · Scan
DIMER_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:659:696_1hf0_B_1 ModCRE Homology model CTTAAAAGGAAATCTAATTAAG Region 659-696 · 1 3D model Open · Scan
TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:213:264_5k5l_F_1 ModCRE Homology model GTAACACACTCGTA Region 213-264 · 1 3D model Open · Scan
TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:999:1050_1f2i_G_1 ModCRE Homology model GGGTAATTACC Region 999-1050 · 1 3D model Open · Scan
TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:999:1050_1f2i_H_1 ModCRE Homology model AGGAACTACCA Region 999-1050 · 1 3D model Open · Scan
TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:999:1052_4gzn_C_1 ModCRE Homology model CCCTGGCCCC Region 999-1052 · 1 3D model Open · Scan
TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:999:1052_4m9v_C_1 ModCRE Homology model CCTCTGCCCC Region 999-1052 · 1 3D model Open · Scan
a0a1b0gw50.af3.0 ModCRE AlphaFold3 model ATGATTCAAATTAATTATTTTATTGTTAAT AlphaFold3 model · ModCRE PWM Open · Scan
a0a1b0gw50.af3.1 ModCRE AlphaFold3 model ATGATTCAAATTAATTATTTTATTGTTAAT AlphaFold3 model · ModCRE PWM Open · Scan
a0a1b0gw50.af3.2 ModCRE AlphaFold3 model GGGGGGTGGGCCCCGGGGGCCCCCGAAAGG AlphaFold3 model · ModCRE PWM Open · Scan
a0a1b0gw50.af3.3 ModCRE AlphaFold3 model GGCCCCCCGGACCTTGGCCCCCCCGCC AlphaFold3 model · ModCRE PWM Open · Scan
a0a1b0gw50.af3.4 ModCRE AlphaFold3 model TATAAATTTATAAAAGTTATTTTAAAAGG AlphaFold3 model · ModCRE PWM Open · Scan
a0a1b0gw50.af3.5 ModCRE AlphaFold3 model GTAAAAATGAATTTTAAAATTATTTTTATT AlphaFold3 model · ModCRE PWM Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 1202 aa
213-264
659-696
999-1073

Region 213-264 1 PWM

Residues
52 aa
Domains
PF05605 · Drought induced 19 protein (Di19), zinc-binding
3D models
1 active PDB
Templates
5K5L
Sources
Predicted = Low
Scan this region Show models

Region 659-696 2 PWM

Residues
38 aa
Domains
No overlapping PFAM annotation recorded
3D models
2 active PDBs
Templates
1AU7, 1HF0
Sources
Predicted = Low
Scan this region Show models

Region 999-1073 4 PWM

Residues
75 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
10 active PDBs · 6 summary rows
Templates
1A1F, 1A1G, 1A1H, 1A1I, 1A1K, 1F2I, 1LLM, 4GZN, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
31 active PDB models 6 summary rows
Region 213-2641 model
Actions
Predicted = Low TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:213:264_5k5l_F_1 5k5l 213-264 View model · PDB
Region 659-6962 models
Actions
Predicted = Low DIMER_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:659:696_1au7_B_1 1au7 659-696 View model · PDB
Predicted = Low DIMER_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:659:696_1hf0_B_1 1hf0 659-696 View model · PDB
Region 999-107310 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:1025:1073_1llm_D_1 1llm 1025-1073 View model · PDB
Predicted = Low TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:999:1050_1f2i_G_1 1f2i 999-1050 View model · PDB
Predicted = Low TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:999:1050_1f2i_H_1 1f2i 999-1050 View model · PDB
Predicted = Low TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:999:1052_4gzn_C_1 4gzn 999-1052 View model · PDB
Predicted = Low TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:999:1052_4m9v_C_1 4m9v 999-1052 View model · PDB
Predicted = Low TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:999:1073_1a1f_A_1 1a1f 999-1073 View model · PDB
Predicted = Low TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:999:1073_1a1g_A_1 1a1g 999-1073 View model · PDB
Predicted = Low TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:999:1073_1a1h_A_1 1a1h 999-1073 View model · PDB
Predicted = Low TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:999:1073_1a1i_A_1 1a1i 999-1073 View model · PDB
Predicted = Low TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:999:1073_1a1k_A_1 1a1k 999-1073 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 1a1h 982:1077 999 1073 P:A · DNA:B,C 46.8% / 63.6% 88 View · PDB TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:999:1073_1a1h_A_1
2 1a1g 982:1077 999 1073 P:A · DNA:B,C 46.8% / 63.6% 89 View · PDB TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:999:1073_1a1g_A_1
3 1a1f 982:1077 999 1073 P:A · DNA:B,C 46.8% / 63.6% 89 View · PDB TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:999:1073_1a1f_A_1
4 1a1k 982:1077 999 1073 P:A · DNA:B,C 45.5% / 63.6% 88 View · PDB TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:999:1073_1a1k_A_1
5 1a1i 982:1077 999 1073 P:A · DNA:B,C 45.5% / 63.6% 88 View · PDB TFS_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:999:1073_1a1i_A_1
1 1llm 982:1077 1025,1025 1073,1073 P:C,D · DNA:A,B 44.9% / 63.3% 56,57 View · PDB DIMER_tr_A0A1B0GW50_A0A1B0GW50_HUMAN:1025:1073_1llm_D_1
Full sequence / unlocalized models18 models
SourceModelTemplateResidues modeledActions
Predicted = Lowa0a1b0gw50.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a1b0gw50.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a1b0gw50.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a1b0gw50.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a1b0gw50.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a1b0gw50.af3.5-Full sequence / not localizedView model · PDB
Predicted = Lowa0a1b0gw50_dimer.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a1b0gw50_dimer.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a1b0gw50_dimer.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a1b0gw50_dimer.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a1b0gw50_dimer.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a1b0gw50_dimer.af3.5-Full sequence / not localizedView model · PDB
Predicted = Lowa0a1b0gw50_monomer.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a1b0gw50_monomer.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a1b0gw50_monomer.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a1b0gw50_monomer.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a1b0gw50_monomer.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a1b0gw50_monomer.af3.5-Full sequence / not localizedView model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
211-262PF05605Drought induced 19 protein (Di19), zinc-bindingoverlaps 213-264
282-304PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
310-330PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
999-1021PF00096Zinc finger, C2H2 typeoverlaps 999-1073
1055-1075PF00096Zinc finger, C2H2 typeoverlaps 999-1073