ModCRE DB

Transcription factor

A0A286R9D9 - HMGB1

Nuclear autoantigen Sp-100 (Nuclear dot-associated Sp100 protein) (Speckled 100 kDa)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 185 aa

11 Generated PWM 11 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE11
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_tr_A0A286R9D9_A0A286R9D9_HUMAN:1:136_5zdz_N_1 ModCRE Homology model ATGAAAAATCGTAACGGGCGCGCGCGGCGGGGG Region 1-136 · 1 3D model Open · Scan
TFS_tr_A0A286R9D9_A0A286R9D9_HUMAN:1:136_5ze0_N_1 ModCRE Homology model AAATAAAATCTTAAAGGAGCGGCGGGCTGCCTACCA Region 1-136 · 1 3D model Open · Scan
TFS_tr_A0A286R9D9_A0A286R9D9_HUMAN:1:136_5ze1_N_1 ModCRE Homology model GAGAGAAATCAGCAATAAGACGCGCGCGGCTGAGAA Region 1-136 · 1 3D model Open · Scan
TFS_tr_A0A286R9D9_A0A286R9D9_HUMAN:1:136_5ze2_N_1 ModCRE Homology model AAGTAAATCAGAGATCGCCGCGCCAGGTCCCGTG Region 1-136 · 1 3D model Open · Scan
TFS_tr_A0A286R9D9_A0A286R9D9_HUMAN:1:137_6cij_N_1 ModCRE Homology model TCCAAATATAAATATAGCGCTGCAGGAAA Region 1-137 · 1 3D model Open · Scan
a0a286r9d9.af3.0 ModCRE AlphaFold3 model CTAAAAATCCCTTTCGCGGGCGGATGCCAT AlphaFold3 model · ModCRE PWM Open · Scan
a0a286r9d9.af3.1 ModCRE AlphaFold3 model GCCAAGGTCCCTACCCCCGCTCGCCGCCGG AlphaFold3 model · ModCRE PWM Open · Scan
a0a286r9d9.af3.2 ModCRE AlphaFold3 model CTGAAAGTCCCAAGACCGCGCCGACGCCAG AlphaFold3 model · ModCRE PWM Open · Scan
a0a286r9d9.af3.3 ModCRE AlphaFold3 model CTGAAGGTCCCGGGGGCGCCTCGCCGCCGC AlphaFold3 model · ModCRE PWM Open · Scan
a0a286r9d9.af3.4 ModCRE AlphaFold3 model CTAAAAATCCCTTTCGCGGGCGGATGCCAT AlphaFold3 model · ModCRE PWM Open · Scan
a0a286r9d9.af3.5 ModCRE AlphaFold3 model CTGAAAGTCCCTAGCCCGCCTCGGCGCGCG AlphaFold3 model · ModCRE PWM Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 185 aa
1-137

Region 1-137 5 PWM

Residues
137 aa
Domains
PF09011 · HMG-box domain PF00505 · HMG (high mobility group) box
3D models
5 active PDBs · 5 summary rows
Templates
5ZDZ, 5ZE0, 5ZE1, 5ZE2, 6CIJ
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
11 active PDB models 5 summary rows
Region 1-1375 models · 5 summary rows
Actions
Predicted = Low TFS_tr_A0A286R9D9_A0A286R9D9_HUMAN:1:136_5zdz_N_1 5zdz 1-136 View model · PDB
Predicted = Low TFS_tr_A0A286R9D9_A0A286R9D9_HUMAN:1:136_5ze0_N_1 5ze0 1-136 View model · PDB
Predicted = Low TFS_tr_A0A286R9D9_A0A286R9D9_HUMAN:1:136_5ze1_N_1 5ze1 1-136 View model · PDB
Predicted = Low TFS_tr_A0A286R9D9_A0A286R9D9_HUMAN:1:136_5ze2_N_1 5ze2 1-136 View model · PDB
Predicted = Low TFS_tr_A0A286R9D9_A0A286R9D9_HUMAN:1:137_6cij_N_1 6cij 1-137 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 6cij 1:149 1 137 P:N · DNA:G,M 86.1% / 87.6% 90 View · PDB TFS_tr_A0A286R9D9_A0A286R9D9_HUMAN:1:137_6cij_N_1
2 5ze2 1:149 1 136 P:N · DNA:G,M 76.5% / 77.9% 90 View · PDB TFS_tr_A0A286R9D9_A0A286R9D9_HUMAN:1:136_5ze2_N_1
3 5ze1 1:149 1 136 P:N · DNA:G,M 76.5% / 77.9% 90 View · PDB TFS_tr_A0A286R9D9_A0A286R9D9_HUMAN:1:136_5ze1_N_1
4 5zdz 1:149 1 136 P:N · DNA:G,M 76.5% / 77.9% 90 View · PDB TFS_tr_A0A286R9D9_A0A286R9D9_HUMAN:1:136_5zdz_N_1
5 5ze0 1:149 1 136 P:N · DNA:G,M 76.5% / 77.9% 89 View · PDB TFS_tr_A0A286R9D9_A0A286R9D9_HUMAN:1:136_5ze0_N_1
Full sequence / unlocalized models6 models
SourceModelTemplateResidues modeledActions
Predicted = Lowa0a286r9d9.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a286r9d9.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a286r9d9.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a286r9d9.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a286r9d9.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a286r9d9.af3.5-Full sequence / not localizedView model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
1-57PF09011HMG-box domainoverlaps 1-137
74-142PF00505HMG (high mobility group) boxoverlaps 1-137