ModCRE DB

Transcription factor

A0A2R8YDQ8 - ZEB2

Zinc finger E-box binding homeobox 2

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 79 aa

20 Generated PWM 14 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)11
MotifPredictionSourceDNA bindingSupportLogoActions
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 63.6% identity Open · Scan
M05844_2.00 NN 70-40% CisBP TCACCTGT 63.4% identity Open · Scan
MA0103.1 NN 70-40% JASPAR CACCTG 63.4% identity Open · Scan
MA0103.2 NN 70-40% JASPAR CCTCACCTG 63.4% identity Open · Scan
M06131_2.00 NN 70-40% CisBP ATGTCAAGCCCAAACAAAACCAAAA 62.5% identity Open · Scan
M07566_2.00 NN 70-40% CisBP TCAAACCATCCTTGC 60.0% identity Open · Scan
M07746_2.00 NN 70-40% CisBP CAGCTGGCGCCCAACATGGGTCCC 56.5% identity Open · Scan
M06108_2.00 NN 70-40% CisBP ACAACAACAAC 54.1% identity Open · Scan
M08357_2.00 NN 70-40% CisBP GAGCCTGCTACTGAGCCTGGG 54.1% identity Open · Scan
M06148_2.00 NN 70-40% CisBP AACAACACTA 50.0% identity Open · Scan
M07590_2.00 NN 70-40% CisBP TTTTTTTCTTTTATTTTTTTTTTTTTTTTTTTT 50.0% identity Open · Scan
ModCRE9
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_A0A2R8YDQ8_A0A2R8YDQ8_HUMAN:43:62_1llm_C_1 ModCRE Homology model TACGCGCGCGAA Region 43-62 · 1 3D model Open · Scan
TFS_tr_A0A2R8YDQ8_A0A2R8YDQ8_HUMAN:26:66_5wjq_D_1 ModCRE Homology model TTGCCCGCCGGGCCG Region 26-66 · 1 3D model Open · Scan
TFS_tr_A0A2R8YDQ8_A0A2R8YDQ8_HUMAN:28:66_6blw_A_1 ModCRE Homology model ATCTACTTAAAA Region 28-66 · 1 3D model Open · Scan
a0a2r8ydq8.af3.0 ModCRE AlphaFold3 model CCCCCCCCCCG AlphaFold3 model · ModCRE PWM Open · Scan
a0a2r8ydq8.af3.1 ModCRE AlphaFold3 model GGGGCGGGCGGG AlphaFold3 model · ModCRE PWM Open · Scan
a0a2r8ydq8.af3.2 ModCRE AlphaFold3 model CGCCCCCCCCA AlphaFold3 model · ModCRE PWM Open · Scan
a0a2r8ydq8.af3.3 ModCRE AlphaFold3 model GGCGGCCGGC AlphaFold3 model · ModCRE PWM Open · Scan
a0a2r8ydq8.af3.4 ModCRE AlphaFold3 model AGCGCGCGGCGC AlphaFold3 model · ModCRE PWM Open · Scan
a0a2r8ydq8.af3.5 ModCRE AlphaFold3 model AGGGCCCC AlphaFold3 model · ModCRE PWM Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 79 aa
26-68

Region 26-68 3 PWM

Residues
43 aa
Domains
No overlapping PFAM annotation recorded
3D models
8 active PDBs · 6 summary rows
Templates
1LLM, 5WJQ, 6B0R, 6BLW, 6E93, 6E94, 7YSF, 8FFZ
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
14 active PDB models 6 summary rows
Region 26-688 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_A0A2R8YDQ8_A0A2R8YDQ8_HUMAN:43:62_1llm_C_1 1llm 43-62 View model · PDB
Predicted = Low TFS_tr_A0A2R8YDQ8_A0A2R8YDQ8_HUMAN:26:66_5wjq_D_1 5wjq 26-66 View model · PDB
Predicted = Low TFS_tr_A0A2R8YDQ8_A0A2R8YDQ8_HUMAN:28:61_7ysf_A_1 7ysf 28-61 View model · PDB
Predicted = Low TFS_tr_A0A2R8YDQ8_A0A2R8YDQ8_HUMAN:28:66_6b0r_D_1 6b0r 28-66 View model · PDB
Predicted = Low TFS_tr_A0A2R8YDQ8_A0A2R8YDQ8_HUMAN:28:66_6blw_A_1 6blw 28-66 View model · PDB
Predicted = Low TFS_tr_A0A2R8YDQ8_A0A2R8YDQ8_HUMAN:43:66_6e93_A_1 6e93 43-66 View model · PDB
Predicted = Low TFS_tr_A0A2R8YDQ8_A0A2R8YDQ8_HUMAN:43:66_6e94_A_1 6e94 43-66 View model · PDB
Predicted = Low TFS_tr_A0A2R8YDQ8_A0A2R8YDQ8_HUMAN:43:68_8ffz_A_1 8ffz 43-68 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 6e94 26:68 43 66 P:A · DNA:C,D 54.2% / 62.5% 21 View · PDB TFS_tr_A0A2R8YDQ8_A0A2R8YDQ8_HUMAN:43:66_6e94_A_1
5 6e93 26:68 43 66 P:A · DNA:C,D 54.2% / 62.5% 21 View · PDB TFS_tr_A0A2R8YDQ8_A0A2R8YDQ8_HUMAN:43:66_6e93_A_1
2 8ffz 26:68 43 68 P:A · DNA:I,J 50.0% / 61.5% 8 View · PDB TFS_tr_A0A2R8YDQ8_A0A2R8YDQ8_HUMAN:43:68_8ffz_A_1
1 7ysf 26:68 28 61 P:A · DNA:B,C 44.1% / 58.8% 30 View · PDB TFS_tr_A0A2R8YDQ8_A0A2R8YDQ8_HUMAN:28:61_7ysf_A_1
1 1llm 26:68 43,43 62,62 P:C,D · DNA:A,B 40.0% / 65.0% 22,23 View · PDB DIMER_tr_A0A2R8YDQ8_A0A2R8YDQ8_HUMAN:43:62_1llm_C_1
3 6b0r 26:68 28 66 P:D · DNA:E,F 39.0% / 48.8% 33 View · PDB TFS_tr_A0A2R8YDQ8_A0A2R8YDQ8_HUMAN:28:66_6b0r_D_1
Full sequence / unlocalized models6 models
SourceModelTemplateResidues modeledActions
Predicted = Lowa0a2r8ydq8.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a2r8ydq8.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a2r8ydq8.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a2r8ydq8.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a2r8ydq8.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a2r8ydq8.af3.5-Full sequence / not localizedView model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Imported domain tags8
Baculo_ME53Rep_fac-A_Czf-C2H2zf-C2H2_4zf-C2H2_6zf-C2H2_jazzf-H2C2_2zf-met