Transcription factor

A0A2R8YEW3 - NOBOX

NOBOX oogenesis homeobox

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 691 aa

24 Generated PWM 38 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)3

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
MA0125.1	NN 70-40%	JASPAR	TAATTGGT	58.6% identity		Open · Scan
M02103_2.00	NN 70-40%	CisBP	AGGTGTAAA	52.9% identity		Open · Scan
M02221_2.00	NN 70-40%	CisBP	CTTAATTGGT	50.9% identity		Open · Scan

ModCRE21

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:272:315_4j19_B_1	ModCRE	Homology model	TCGGGCCATTAATATTTT	Region 272-315 · 1 3D model		Open · Scan
DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:272:318_1fjl_A_1	ModCRE	Homology model	CTGATTCAATCAG	Region 272-318 · 1 3D model		Open · Scan
DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:273:318_3a01_B_1	ModCRE	Homology model	TTTTCAATTAATGGCCT	Region 273-318 · 1 3D model		Open · Scan
DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:274:318_1hdd_D_1	ModCRE	Homology model	TGGGTCAATTAAAAGTT	Region 274-318 · 1 3D model		Open · Scan
DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:274:318_3hdd_B_1	ModCRE	Homology model	GCGATCTAATTGAGCCA	Region 274-318 · 1 3D model		Open · Scan
DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:347:363_5hod_D_1	ModCRE	Homology model	AAAATTTTTAAAAATTTT	Region 347-363 · 1 3D model		Open · Scan
DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:350:361_1fjl_A_1	ModCRE	Homology model	CTAAGTTAATTAA	Region 350-361 · 1 3D model		Open · Scan
DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:350:361_1hdd_D_1	ModCRE	Homology model	GGCAAAAATTTAAAA	Region 350-361 · 1 3D model		Open · Scan
DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:350:361_3hdd_A_1	ModCRE	Homology model	TGGAAAAATTTTTAAA	Region 350-361 · 1 3D model		Open · Scan
DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:350:361_4qtr_B_1	ModCRE	Homology model	GTAAATTTAGTTTA	Region 350-361 · 1 3D model		Open · Scan
TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:350:361_3a01_B_1	ModCRE	Homology model	GGTAAAAATTATAAAG	Region 350-361 · 1 3D model		Open · Scan
TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:350:363_3lnq_A_1	ModCRE	Homology model	GCAAAAAATTTAAA	Region 350-363 · 1 3D model		Open · Scan
TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:350:364_2lkx_A_1	ModCRE	Homology model	CAAAAAATTTTTA	Region 350-364 · 1 3D model		Open · Scan
TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:350:366_2me6_A_1	ModCRE	Homology model	TATAAAATTTTTGT	Region 350-366 · 1 3D model		Open · Scan
TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:350:368_1ahd_P_1	ModCRE	Homology model	TTGAGTAATTTGCG	Region 350-368 · 1 3D model		Open · Scan
a0a2r8yew3.af3.0	ModCRE	AlphaFold3 model	CCCCAAATTTGGCAACCG	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a2r8yew3.af3.1	ModCRE	AlphaFold3 model	CCCCAAATTTGGCAACCG	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a2r8yew3.af3.2	ModCRE	AlphaFold3 model	CCCCAAATTTGTTCCCAAAAAAAAAAAAAA	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a2r8yew3.af3.3	ModCRE	AlphaFold3 model	AACTAAATTGGGCCCAA	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a2r8yew3.af3.4	ModCRE	AlphaFold3 model	ACCCAAATTGGGCCCCA	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a2r8yew3.af3.5	ModCRE	AlphaFold3 model	CACCAAATTGGGCCCA	AlphaFold3 model · ModCRE PWM		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 691 aa

272-318

347-368

Region 272-318 5 PWM

Residues

47 aa

Domains

PF00046 · Homeodomain

3D models

10 active PDBs · 10 summary rows

Templates

1FJL, 1HDD, 2LKX, 3A01, 3CMY, 3HDD, 3LNQ, 4J19

Sources

Predicted = Low

Scan this region Show models

Region 347-368 10 PWM

Residues

22 aa

Domains

No overlapping PFAM annotation recorded

3D models

10 active PDBs

Templates

1AHD, 1FJL, 1HDD, 2LKX, 2ME6, 3A01, 3HDD, 3LNQ, ...

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

38 active PDB models 10 summary rows

Region 272-31810 models · 10 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:272:315_4j19_B_1	4j19	272-315	View model · PDB
Predicted = Low	DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:272:318_1fjl_A_1	1fjl	272-318	View model · PDB
Predicted = Low	DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:273:318_3a01_B_1	3a01	273-318	View model · PDB
Predicted = Low	DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:274:318_1hdd_D_1	1hdd	274-318	View model · PDB
Predicted = Low	DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:274:318_3hdd_B_1	3hdd	274-318	View model · PDB
Predicted = Low	TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:272:318_1fjl_A_1	1fjl	272-318	View model · PDB
Predicted = Low	TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:272:318_2lkx_A_1	2lkx	272-318	View model · PDB
Predicted = Low	TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:272:318_3cmy_A_1	3cmy	272-318	View model · PDB
Predicted = Low	TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:273:318_3a01_B_1	3a01	273-318	View model · PDB
Predicted = Low	TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:276:318_3lnq_A_1	3lnq	276-318	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
1	3lnq	272:318	276	318	P:A · DNA:B,C	53.5% / 62.8%	74	View · PDB TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:276:318_3lnq_A_1
1	3a01	272:318	272,273	316,318	P:A,B · DNA:C,D	50.0% / 63.0%	57,80	View · PDB DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:273:318_3a01_B_1
2	3a01	272:318	272,273	316,318	P:A,B · DNA:C,D	50.0% / 63.0%	57,80	View · PDB TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:273:318_3a01_B_1
3	3cmy	272:318	272	318	P:A · DNA:B,C	42.6% / 68.1%	78	View · PDB TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:272:318_3cmy_A_1
4	2lkx	272:318	272	318	P:A · DNA:B,C	42.6% / 59.6%	69	View · PDB TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:272:318_2lkx_A_1
2	1fjl	272:318	272,272	318,318	P:A,B · DNA:D,E	40.4% / 63.8%	72,82	View · PDB DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:272:318_1fjl_A_1
5	1fjl	272:318	272,272	318,318	P:A,B · DNA:D,E	40.4% / 63.8%	72,82	View · PDB TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:272:318_1fjl_A_1
3	4j19	272:318	275,272	315,315	P:A,B · DNA:C,D	36.4% / 52.3%	53,57	View · PDB DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:272:315_4j19_B_1
4	3hdd	272:318	276,274	318,318	P:A,B · DNA:C,D	26.7% / 60.0%	78,80	View · PDB DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:274:318_3hdd_B_1
5	1hdd	272:318	274,274	318,318	P:C,D · DNA:A,B	26.7% / 60.0%	78,78	View · PDB DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:274:318_1hdd_D_1

Region 347-36810 models

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:347:363_5hod_D_1	5hod	347-363	View model · PDB
Predicted = Low	DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:350:361_1fjl_A_1	1fjl	350-361	View model · PDB
Predicted = Low	DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:350:361_1hdd_D_1	1hdd	350-361	View model · PDB
Predicted = Low	DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:350:361_3hdd_A_1	3hdd	350-361	View model · PDB
Predicted = Low	DIMER_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:350:361_4qtr_B_1	4qtr	350-361	View model · PDB
Predicted = Low	TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:350:361_3a01_B_1	3a01	350-361	View model · PDB
Predicted = Low	TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:350:363_3lnq_A_1	3lnq	350-363	View model · PDB
Predicted = Low	TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:350:364_2lkx_A_1	2lkx	350-364	View model · PDB
Predicted = Low	TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:350:366_2me6_A_1	2me6	350-366	View model · PDB
Predicted = Low	TFS_tr_A0A2R8YEW3_A0A2R8YEW3_HUMAN:350:368_1ahd_P_1	1ahd	350-368	View model · PDB

Full sequence / unlocalized models18 models

Source	Model	Template	Residues modeled	Actions
Predicted = Low	a0a2r8yew3.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a2r8yew3.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a2r8yew3.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a2r8yew3.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a2r8yew3.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a2r8yew3.af3.5	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a2r8yew3_dimer.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a2r8yew3_dimer.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a2r8yew3_dimer.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a2r8yew3_dimer.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a2r8yew3_dimer.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a2r8yew3_dimer.af3.5	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a2r8yew3_monomer.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a2r8yew3_monomer.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a2r8yew3_monomer.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a2r8yew3_monomer.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a2r8yew3_monomer.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a2r8yew3_monomer.af3.5	-	Full sequence / not localized	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
273-317	PF00046	Homeodomain	overlaps 272-318