ModCRE DB

Transcription factor

A0A3B3ITE4 - ZNF23

Zinc finger protein 23

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 686 aa

81 Generated PWM 16 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)70
MotifPredictionSourceDNA bindingSupportLogoActions
M04653_2.00 NN 70-40% CisBP GGTACGGTTGTCCATGTTGCAA 67.1% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 67.0% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 67.0% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 65.8% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 65.8% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 65.1% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 64.7% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 64.7% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 64.7% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 64.7% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 63.5% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 63.5% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 62.9% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 62.8% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 62.8% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 61.9% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 61.5% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 61.1% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 61.0% identity Open · Scan
M08267_2.00 NN 70-40% CisBP CAGTTTCATTTTCC 60.9% identity Open · Scan
M08365_2.00 NN 70-40% CisBP GCCAGCAGCCATCAG 60.2% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 60.1% identity Open · Scan
M08309_2.00 NN 70-40% CisBP AAAAACCCCCCTGCAGAGCCCAGCCCT 59.9% identity Open · Scan
M07610_2.00 NN 70-40% CisBP CCTTCTTCCTCCCCCCTGCCCACC 58.6% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 58.2% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 57.7% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 57.6% identity Open · Scan
M08254_2.00 NN 70-40% CisBP CTGCCCTGGGACTTT 57.4% identity Open · Scan
M07753_2.00 NN 70-40% CisBP TGCATTCCTTGGCTTGTG 56.8% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 56.7% identity Open · Scan
M07648_2.00 NN 70-40% CisBP GCTTGCAAAAAAAATTTAACTCCCAGCTC 56.0% identity Open · Scan
M08908_2.00 NN 70-40% CisBP GCTGCTGCTTCTGCTG 56.0% identity Open · Scan
M08934_2.00 NN 70-40% CisBP GCTGTACCTGCTTATTAGGC 56.0% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 55.4% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 55.1% identity Open · Scan
M04621_2.00 NN 70-40% CisBP AGCAATTCCGCTCA 54.8% identity Open · Scan
M07649_2.00 NN 70-40% CisBP CCCCCCCCCCCCTCAGGAATGCC 54.7% identity Open · Scan
MA1154.1 NN 70-40% JASPAR CTTTCCCACAACACGAC 54.6% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 54.5% identity Open · Scan
M08373_2.00 NN 70-40% CisBP CCCCCTGGCTCTTCCTCT 54.0% identity Open · Scan
M07683_2.00 NN 70-40% CisBP GTGGGAAAGCCT 53.7% identity Open · Scan
MA1601.1 NN 70-40% JASPAR ATGTGGGAAA 53.7% identity Open · Scan
M00786_2.00 NN 70-40% CisBP TATATATAT 53.3% identity Open · Scan
M08540_2.00 NN 70-40% CisBP CCCCT 53.3% identity Open · Scan
M00645_2.00 NN 70-40% CisBP CGCCCACGCA 53.2% identity Open · Scan
M07581_2.00 NN 70-40% CisBP TCCCCTGTGCTTCTCTCCCCT 53.2% identity Open · Scan
M08392_2.00 NN 70-40% CisBP CTTCACCTGCTGAGG 53.2% identity Open · Scan
MA1602.1 NN 70-40% JASPAR CGTCTACACGGG 53.1% identity Open · Scan
M08901_2.00 NN 70-40% CisBP CCAGTTCACACC 52.8% identity Open · Scan
M07562_2.00 NN 70-40% CisBP GAAAAAAAC 52.3% identity Open · Scan
MA1656.1 NN 70-40% JASPAR CCAAGCCCAACCAG 52.2% identity Open · Scan
M04536_2.00 NN 70-40% CisBP ACGTAACCCGATACC 52.1% identity Open · Scan
M04505_2.00 NN 70-40% CisBP AGCTTTTCCCACAC 52.0% identity Open · Scan
M07699_2.00 NN 70-40% CisBP GGTTTAT 52.0% identity Open · Scan
M08367_2.00 NN 70-40% CisBP GGGGTGATGACCACTCTGGCTTCTTAC 51.9% identity Open · Scan
M07746_2.00 NN 70-40% CisBP CAGCTGGCGCCCAACATGGGTCCC 51.6% identity Open · Scan
M07678_2.00 NN 70-40% CisBP CCCGCCCCCTCCTCCCCCTTCCCACCC 51.3% identity Open · Scan
M00764_2.00 NN 70-40% CisBP GTCTACAC 51.2% identity Open · Scan
M01474_2.00 NN 70-40% CisBP CGCCGATCAC 50.9% identity Open · Scan
M07627_2.00 NN 70-40% CisBP CAGTCACCTTCTGG 50.8% identity Open · Scan
M01456_2.00 NN 70-40% CisBP GTGATCGGCG 50.7% identity Open · Scan
M07628_2.00 NN 70-40% CisBP AGTGGTTCTGCTTCT 50.7% identity Open · Scan
M08366_2.00 NN 70-40% CisBP GTTTGCTGCTTACAA 50.6% identity Open · Scan
M00609_2.00 NN 70-40% CisBP GGAAGCCCTA 50.4% identity Open · Scan
M08247_2.00 NN 70-40% CisBP AAAAATAACAAACGG 50.4% identity Open · Scan
M08314_2.00 NN 70-40% CisBP ATTCATCAAGGTCCTCAACAATGG 50.3% identity Open · Scan
M07727_2.00 NN 70-40% CisBP CGCCGCCTCCCC 50.2% identity Open · Scan
MA0528.1 NN 70-40% JASPAR GGAGGAGGAGGGGGAGGAGGA 50.1% identity Open · Scan
M00132_2.00 NN 70-40% CisBP TGCTACCGTT 50.0% identity Open · Scan
M07607_2.00 NN 70-40% CisBP GGCTCCACG 50.0% identity Open · Scan
ModCRE11
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:17:44_1ram_B_1 ModCRE Homology model CGAGACCCCCT Region 17-44 · 1 3D model Open · Scan
DIMER_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:17:44_2ram_B_1 ModCRE Homology model CGAGGGCCCC Region 17-44 · 1 3D model Open · Scan
DIMER_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:17:44_5u01_B_1 ModCRE Homology model GGGGGGCCCC Region 17-44 · 1 3D model Open · Scan
DIMER_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:265:316_1llm_D_1 ModCRE Homology model TCCGGGCCCGGA Region 265-316 · 1 3D model Open · Scan
TFS_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:320:430_5ei9_E_1 ModCRE Homology model CCCGAGGGGGGGGTGGG Region 320-430 · 1 3D model Open · Scan
a0a3b3ite4.af3.0 ModCRE AlphaFold3 model AAAACCTAAAGCGCGTAACAAACTTGCCCA AlphaFold3 model · ModCRE PWM Open · Scan
a0a3b3ite4.af3.1 ModCRE AlphaFold3 model CCTTTTCCTCTTGCCACACCTCCCCCCCCC AlphaFold3 model · ModCRE PWM Open · Scan
a0a3b3ite4.af3.2 ModCRE AlphaFold3 model AAAAGAAAAAGGCGCTAGCGAGCCTTGCAG AlphaFold3 model · ModCRE PWM Open · Scan
a0a3b3ite4.af3.3 ModCRE AlphaFold3 model AAAACCTAAAGCGCGTAACAAACTTGCCCA AlphaFold3 model · ModCRE PWM Open · Scan
a0a3b3ite4.af3.4 ModCRE AlphaFold3 model GCTACTCCTAAAAAAGCCACAAAAGGCGTA AlphaFold3 model · ModCRE PWM Open · Scan
a0a3b3ite4.af3.5 ModCRE AlphaFold3 model AGACTTATACTGCTAGTTTTAAAAAGCTTT AlphaFold3 model · ModCRE PWM Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 686 aa
17-44
236-654

Region 17-44 3 PWM

Residues
28 aa
Domains
PF01352 · KRAB box
3D models
3 active PDBs
Templates
1RAM, 2RAM, 5U01
Sources
Predicted = Low
Scan this region Show models

Region 236-654 2 PWM

Residues
419 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
7 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
16 active PDB models 6 summary rows
Region 17-443 models
Actions
Predicted = Low DIMER_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:17:44_1ram_B_1 1ram 17-44 View model · PDB
Predicted = Low DIMER_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:17:44_2ram_B_1 2ram 17-44 View model · PDB
Predicted = Low DIMER_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:17:44_5u01_B_1 5u01 17-44 View model · PDB
Region 236-6547 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:265:316_1llm_D_1 1llm 265-316 View model · PDB
Predicted = Low TFS_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:236:514_5wjq_D_1 5wjq 236-514 View model · PDB
Predicted = Low TFS_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:320:430_5ei9_E_1 5ei9 320-430 View model · PDB
Predicted = Low TFS_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:351:641_7w1m_H_1 7w1m 351-641 View model · PDB
Predicted = Low TFS_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:378:654_5v3j_E_1 5v3j 378-654 View model · PDB
Predicted = Low TFS_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:378:654_5v3m_C_1 5v3m 378-654 View model · PDB
Predicted = Low TFS_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:416:569_2i13_A_1 2i13 416-569 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 2i13 213:641 416 569 P:A · DNA:C,D 57.8% / 68.8% 100 View · PDB TFS_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:416:569_2i13_A_1
1 5wjq 213:641 236 514 P:D · DNA:A,B 54.5% / 72.0% 99 View · PDB TFS_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:236:514_5wjq_D_1
2 5v3m 213:641 378 654 P:C · DNA:A,B 54.2% / 70.4% 100 View · PDB TFS_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:378:654_5v3m_C_1
3 5v3j 213:641 378 654 P:E · DNA:A,B 54.2% / 70.4% 100 View · PDB TFS_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:378:654_5v3j_E_1
1 1llm 213:641 265,265 316,316 P:C,D · DNA:A,B 44.2% / 63.5% 59,61 View · PDB DIMER_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:265:316_1llm_D_1
5 7w1m 213:641 351 641 P:H · DNA:F,G 35.0% / 53.7% 90 View · PDB TFS_tr_A0A3B3ITE4_A0A3B3ITE4_HUMAN:351:641_7w1m_H_1
Full sequence / unlocalized models6 models
SourceModelTemplateResidues modeledActions
Predicted = Lowa0a3b3ite4.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a3b3ite4.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a3b3ite4.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a3b3ite4.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a3b3ite4.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a3b3ite4.af3.5-Full sequence / not localizedView model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
13-54PF01352KRAB boxoverlaps 17-44
239-261PF00096Zinc finger, C2H2 typeoverlaps 236-654
267-289PF00096Zinc finger, C2H2 typeoverlaps 236-654
295-317PF00096Zinc finger, C2H2 typeoverlaps 236-654
351-373PF00096Zinc finger, C2H2 typeoverlaps 236-654
379-401PF00096Zinc finger, C2H2 typeoverlaps 236-654
407-429PF00096Zinc finger, C2H2 typeoverlaps 236-654
435-457PF00096Zinc finger, C2H2 typeoverlaps 236-654
463-485PF00096Zinc finger, C2H2 typeoverlaps 236-654
491-513PF00096Zinc finger, C2H2 typeoverlaps 236-654
519-541PF00096Zinc finger, C2H2 typeoverlaps 236-654
547-569PF00096Zinc finger, C2H2 typeoverlaps 236-654
575-597PF00096Zinc finger, C2H2 typeoverlaps 236-654
603-625PF00096Zinc finger, C2H2 typeoverlaps 236-654
631-653PF00096Zinc finger, C2H2 typeoverlaps 236-654
659-681PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions