ModCRE DB

Transcription factor

A0A494C069

C2H2-type domain-containing protein

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 634 aa

51 Generated PWM 12 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)39
MotifPredictionSourceDNA bindingSupportLogoActions
M07628_2.00 NN 70-40% CisBP AGTGGTTCTGCTTCT 66.9% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 65.4% identity Open · Scan
M04653_2.00 NN 70-40% CisBP GGTACGGTTGTCCATGTTGCAA 62.9% identity Open · Scan
M07627_2.00 NN 70-40% CisBP CAGTCACCTTCTGG 62.2% identity Open · Scan
M07733_2.00 NN 70-40% CisBP TCTTTCTCTCTCTCC 60.8% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 60.7% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 60.7% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 60.7% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 59.5% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 59.5% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 59.5% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 59.5% identity Open · Scan
M07659_2.00 NN 70-40% CisBP GTCTTCCAAGTAGCTGGTGTT 59.5% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 58.3% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 58.3% identity Open · Scan
M08908_2.00 NN 70-40% CisBP GCTGCTGCTTCTGCTG 56.0% identity Open · Scan
M07770_2.00 NN 70-40% CisBP CTTGGACTT 54.2% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 54.1% identity Open · Scan
M06179_2.00 NN 70-40% CisBP TAAGCCTATAGA 53.7% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 53.4% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 53.4% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 53.1% identity Open · Scan
M08917_2.00 NN 70-40% CisBP GCTGAGCCATGTGGGGTGCT 52.4% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 52.3% identity Open · Scan
M07731_2.00 NN 70-40% CisBP TTTCCCAGCAGCAACAGCACCGCCCCCCCC 52.3% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 51.9% identity Open · Scan
M05844_2.00 NN 70-40% CisBP TCACCTGT 51.5% identity Open · Scan
MA0103.1 NN 70-40% JASPAR CACCTG 51.5% identity Open · Scan
MA0103.2 NN 70-40% JASPAR CCTCACCTG 51.5% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 51.3% identity Open · Scan
MA1588.1 NN 70-40% JASPAR GAATTCTTGGTTGAC 51.2% identity Open · Scan
M08366_2.00 NN 70-40% CisBP GTTTGCTGCTTACAA 51.0% identity Open · Scan
M00149_2.00 NN 70-40% CisBP CGTACGCC 50.8% identity Open · Scan
M06135_2.00 NN 70-40% CisBP CAGCCACGCCCACCT 50.7% identity Open · Scan
M08254_2.00 NN 70-40% CisBP CTGCCCTGGGACTTT 50.7% identity Open · Scan
M00135_2.00 NN 70-40% CisBP AGCCCCCCAA 50.0% identity Open · Scan
M00645_2.00 NN 70-40% CisBP CGCCCACGCA 50.0% identity Open · Scan
M08367_2.00 NN 70-40% CisBP GGGGTGATGACCACTCTGGCTTCTTAC 50.0% identity Open · Scan
MA0694.1 NN 70-40% JASPAR GCGACCACCGAA 50.0% identity Open · Scan
ModCRE12
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_A0A494C069_A0A494C069_HUMAN:191:240_1llm_D_1 ModCRE Homology model TCGCGGCGCGAA Region 191-240 · 1 3D model Open · Scan
TFS_tr_A0A494C069_A0A494C069_HUMAN:105:339_5v3j_E_1 ModCRE Homology model GCCAGCCTCTCCCCCGAGTCCCCG Region 105-339 · 1 3D model Open · Scan
TFS_tr_A0A494C069_A0A494C069_HUMAN:105:339_5v3m_C_1 ModCRE Homology model TCCCCCTAGGTGCCCGGCTGGGCCC Region 105-339 · 1 3D model Open · Scan
TFS_tr_A0A494C069_A0A494C069_HUMAN:106:339_5wjq_D_1 ModCRE Homology model TCCCCCAGGGGGCCGGGCCGCCGGG Region 106-339 · 1 3D model Open · Scan
TFS_tr_A0A494C069_A0A494C069_HUMAN:128:271_2i13_A_1 ModCRE Homology model ATTCTAAAACTAACTCTTTTT Region 128-271 · 1 3D model Open · Scan
TFS_tr_A0A494C069_A0A494C069_HUMAN:190:300_5ei9_E_1 ModCRE Homology model CGAAAGTTACGCGGGCC Region 190-300 · 1 3D model Open · Scan
a0a494c069.af3.0 ModCRE AlphaFold3 model TAGGAAGGTCGTGGGAGGGGGGCAGGAACC AlphaFold3 model · ModCRE PWM Open · Scan
a0a494c069.af3.1 ModCRE AlphaFold3 model CTTTGGAACAGATGAAAAACCGTTAAT AlphaFold3 model · ModCRE PWM Open · Scan
a0a494c069.af3.2 ModCRE AlphaFold3 model TAGGAAGGTCGTGGGAGGGGGGCAGGAACC AlphaFold3 model · ModCRE PWM Open · Scan
a0a494c069.af3.3 ModCRE AlphaFold3 model TAGGAACAGGGGGGGCCGGGCGGGCGGG AlphaFold3 model · ModCRE PWM Open · Scan
a0a494c069.af3.4 ModCRE AlphaFold3 model TAGGAACGTGGGGGGAGAACAACAAGAACC AlphaFold3 model · ModCRE PWM Open · Scan
a0a494c069.af3.5 ModCRE AlphaFold3 model TCGGGTTCCCCGGGTCCCCCCCGGGTA AlphaFold3 model · ModCRE PWM Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 634 aa
105-339

Region 105-339 6 PWM

Residues
235 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
12 active PDB models 6 summary rows
Region 105-3396 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_A0A494C069_A0A494C069_HUMAN:191:240_1llm_D_1 1llm 191-240 View model · PDB
Predicted = Low TFS_tr_A0A494C069_A0A494C069_HUMAN:105:339_5v3j_E_1 5v3j 105-339 View model · PDB
Predicted = Low TFS_tr_A0A494C069_A0A494C069_HUMAN:105:339_5v3m_C_1 5v3m 105-339 View model · PDB
Predicted = Low TFS_tr_A0A494C069_A0A494C069_HUMAN:106:339_5wjq_D_1 5wjq 106-339 View model · PDB
Predicted = Low TFS_tr_A0A494C069_A0A494C069_HUMAN:128:271_2i13_A_1 2i13 128-271 View model · PDB
Predicted = Low TFS_tr_A0A494C069_A0A494C069_HUMAN:190:300_5ei9_E_1 5ei9 190-300 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
5 5ei9 105:339 190 300 P:E · DNA:A,B 52.3% / 70.3% 100 View · PDB TFS_tr_A0A494C069_A0A494C069_HUMAN:190:300_5ei9_E_1
4 2i13 105:339 128 271 P:A · DNA:C,D 49.3% / 66.0% 93 View · PDB TFS_tr_A0A494C069_A0A494C069_HUMAN:128:271_2i13_A_1
1 1llm 105:339 191,191 240,240 P:C,D · DNA:A,B 46.0% / 60.0% 57,58 View · PDB DIMER_tr_A0A494C069_A0A494C069_HUMAN:191:240_1llm_D_1
2 5v3m 105:339 105 339 P:C · DNA:A,B 43.2% / 62.7% 84 View · PDB TFS_tr_A0A494C069_A0A494C069_HUMAN:105:339_5v3m_C_1
3 5v3j 105:339 105 339 P:E · DNA:A,B 43.2% / 62.7% 84 View · PDB TFS_tr_A0A494C069_A0A494C069_HUMAN:105:339_5v3j_E_1
1 5wjq 105:339 106 339 P:D · DNA:A,B 43.0% / 62.6% 83 View · PDB TFS_tr_A0A494C069_A0A494C069_HUMAN:106:339_5wjq_D_1
Full sequence / unlocalized models6 models
SourceModelTemplateResidues modeledActions
Predicted = Lowa0a494c069.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a494c069.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a494c069.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a494c069.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a494c069.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a494c069.af3.5-Full sequence / not localizedView model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
137-159PF00096Zinc finger, C2H2 typeoverlaps 105-339
193-215PF00096Zinc finger, C2H2 typeoverlaps 105-339
221-243PF00096Zinc finger, C2H2 typeoverlaps 105-339