Transcription factor

A0A494C0U8 - ZNF283

Zinc finger protein 283

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 643 aa

82 Generated PWM 24 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)70

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	68.2% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	62.3% identity		Open · Scan
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	62.3% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	62.3% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	61.1% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	61.1% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	60.3% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	60.0% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	60.0% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	60.0% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	60.0% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	59.8% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	59.7% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	59.6% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	59.4% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	59.2% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	58.8% identity		Open · Scan
M07658_2.00	NN 70-40%	CisBP	CCGCCGCAGCCGCCG	58.5% identity		Open · Scan
M08309_2.00	NN 70-40%	CisBP	AAAAACCCCCCTGCAGAGCCCAGCCCT	57.9% identity		Open · Scan
M07753_2.00	NN 70-40%	CisBP	TGCATTCCTTGGCTTGTG	57.3% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	57.2% identity		Open · Scan
M05853_2.00	NN 70-40%	CisBP	CCACCTTTAGCCATATCT	56.6% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	56.4% identity		Open · Scan
M07693_2.00	NN 70-40%	CisBP	CTCCTGTGTGTGCCTTGGCTG	56.0% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	55.8% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	55.6% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	55.3% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	55.1% identity		Open · Scan
M04611_2.00	NN 70-40%	CisBP	CTTTCGGACAC	55.1% identity		Open · Scan
M08263_2.00	NN 70-40%	CisBP	ATCTCGGCACTTTGGGAGGCCA	55.1% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	55.0% identity		Open · Scan
M07729_2.00	NN 70-40%	CisBP	CCAGACTGCCTGCCAAAACCCCCT	54.9% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	54.7% identity		Open · Scan
M07610_2.00	NN 70-40%	CisBP	CCTTCTTCCTCCCCCCTGCCCACC	54.7% identity		Open · Scan
M08395_2.00	NN 70-40%	CisBP	GCTGCCTACTCTTCC	54.6% identity		Open · Scan
M07648_2.00	NN 70-40%	CisBP	GCTTGCAAAAAAAATTTAACTCCCAGCTC	54.5% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	54.3% identity		Open · Scan
M07649_2.00	NN 70-40%	CisBP	CCCCCCCCCCCCTCAGGAATGCC	54.0% identity		Open · Scan
M07712_2.00	NN 70-40%	CisBP	ACATTTTTTTAATCTAAAAAAACATTTACA	54.0% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	53.7% identity		Open · Scan
M07588_2.00	NN 70-40%	CisBP	TCCTTCCCTCTTTCC	53.2% identity		Open · Scan
M07689_2.00	NN 70-40%	CisBP	ACCCAGGCTCCTTCCATCTTGTGGCTC	53.2% identity		Open · Scan
M07727_2.00	NN 70-40%	CisBP	CGCCGCCTCCCC	53.2% identity		Open · Scan
M08901_2.00	NN 70-40%	CisBP	CCAGTTCACACC	53.2% identity		Open · Scan
M07634_2.00	NN 70-40%	CisBP	AAACGTCCACG	53.1% identity		Open · Scan
M01456_2.00	NN 70-40%	CisBP	GTGATCGGCG	52.8% identity		Open · Scan
M04536_2.00	NN 70-40%	CisBP	ACGTAACCCGATACC	52.6% identity		Open · Scan
M01474_2.00	NN 70-40%	CisBP	CGCCGATCAC	52.5% identity		Open · Scan
M07700_2.00	NN 70-40%	CisBP	ATGTTGTGAGGAAGCCCA	52.4% identity		Open · Scan
M08330_2.00	NN 70-40%	CisBP	TGGGTGCCGGACTGCTGTTCC	52.4% identity		Open · Scan
M08859_2.00	NN 70-40%	CisBP	CATTTTTTCCTCCTAGGCCT	52.4% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	52.3% identity		Open · Scan
M04480_2.00	NN 70-40%	CisBP	ATTGATTACCCACCCTAC	52.2% identity		Open · Scan
M04465_2.00	NN 70-40%	CisBP	GTGATTCTTATCTTATCCTT	52.1% identity		Open · Scan
M00786_2.00	NN 70-40%	CisBP	TATATATAT	52.0% identity		Open · Scan
M08985_2.00	NN 70-40%	CisBP	TGAGGACCTACTGTGTGCC	52.0% identity		Open · Scan
M07717_2.00	NN 70-40%	CisBP	GGCTCCGCCCCC	51.8% identity		Open · Scan
M07605_2.00	NN 70-40%	CisBP	TATTTTTTTTTATTTTTTTTTTTTTTTTTT	51.5% identity		Open · Scan
M08255_2.00	NN 70-40%	CisBP	CTCTTCCGGT	51.2% identity		Open · Scan
MA1656.1	NN 70-40%	JASPAR	CCAAGCCCAACCAG	51.2% identity		Open · Scan
MA1154.1	NN 70-40%	JASPAR	CTTTCCCACAACACGAC	51.0% identity		Open · Scan
M07587_2.00	NN 70-40%	CisBP	CCCCCTCCCCAGTCGAGCCCCCGC	50.7% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	50.7% identity		Open · Scan
MA1589.1	NN 70-40%	JASPAR	TAGGAGTGGAATTGCTGGGTC	50.5% identity		Open · Scan
M08274_2.00	NN 70-40%	CisBP	TTACTTGCAGCCCAACGCATTCCTAAC	50.4% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	50.4% identity		Open · Scan
M07678_2.00	NN 70-40%	CisBP	CCCGCCCCCTCCTCCCCCTTCCCACCC	50.2% identity		Open · Scan
M08367_2.00	NN 70-40%	CisBP	GGGGTGATGACCACTCTGGCTTCTTAC	50.1% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	50.1% identity		Open · Scan
M08934_2.00	NN 70-40%	CisBP	GCTGTACCTGCTTATTAGGC	50.0% identity		Open · Scan

ModCRE12

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
DIMER_tr_A0A494C0U8_A0A494C0U8_HUMAN:505:556_1llm_D_1	ModCRE	Homology model	TTCGCGCGCGAG	Region 505-556 · 1 3D model		Open · Scan
TFS_tr_A0A494C0U8_A0A494C0U8_HUMAN:252:530_5wjq_D_1	ModCRE	Homology model	GGGGCAATAAAAATGAGTTAAGGGCCCA	Region 252-530 · 1 3D model		Open · Scan
TFS_tr_A0A494C0U8_A0A494C0U8_HUMAN:255:553_7w1m_H_1	ModCRE	Homology model	TTTGGGGCGGATTGGGTCGGCGCGGGGCTTGGGGGGGCATGGT	Region 255-553 · 1 3D model		Open · Scan
TFS_tr_A0A494C0U8_A0A494C0U8_HUMAN:310:586_5v3j_E_1	ModCRE	Homology model	ACCCCGGGGGGGCCCAGGGGCCCGGG	Region 310-586 · 1 3D model		Open · Scan
TFS_tr_A0A494C0U8_A0A494C0U8_HUMAN:310:586_5v3m_C_1	ModCRE	Homology model	ACAGGGTGAGCCCCCCGGGGGGCTTT	Region 310-586 · 1 3D model		Open · Scan
TFS_tr_A0A494C0U8_A0A494C0U8_HUMAN:404:557_2i13_A_1	ModCRE	Homology model	ACTTAGCTACTGCCTCTTCAA	Region 404-557 · 1 3D model		Open · Scan
a0a494c0u8.af3.0	ModCRE	AlphaFold3 model	GAGTGTCTCTTAGTAGCTAGTGGCTATAGT	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a494c0u8.af3.1	ModCRE	AlphaFold3 model	AAGGGGGGGGGGGGGGGGGAGGGGGGGGGT	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a494c0u8.af3.2	ModCRE	AlphaFold3 model	GTCTACTTACCCTCTTCTACTACTAACAAG	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a494c0u8.af3.3	ModCRE	AlphaFold3 model	TAAAACTCTCTAGGAGCTGGGGTTTTTAGT	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a494c0u8.af3.4	ModCRE	AlphaFold3 model	GAGTGTCTCTTAGTAGCTAGTGGCTATAGT	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a494c0u8.af3.5	ModCRE	AlphaFold3 model	CCCAGGGGGGCCGGGGGGGGGGGGGGGGGG	AlphaFold3 model · ModCRE PWM		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 643 aa

252-586

Region 252-586 6 PWM

Residues

335 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF13912 · C2H2-type zinc finger PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF13912 · C2H2-type zinc finger PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

6 active PDBs · 6 summary rows

Templates

1LLM, 2I13, 5V3J, 5V3M, 5WJQ, 7W1M

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

24 active PDB models 6 summary rows

Region 252-5866 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_tr_A0A494C0U8_A0A494C0U8_HUMAN:505:556_1llm_D_1	1llm	505-556	View model · PDB
Predicted = Low	TFS_tr_A0A494C0U8_A0A494C0U8_HUMAN:252:530_5wjq_D_1	5wjq	252-530	View model · PDB
Predicted = Low	TFS_tr_A0A494C0U8_A0A494C0U8_HUMAN:255:553_7w1m_H_1	7w1m	255-553	View model · PDB
Predicted = Low	TFS_tr_A0A494C0U8_A0A494C0U8_HUMAN:310:586_5v3j_E_1	5v3j	310-586	View model · PDB
Predicted = Low	TFS_tr_A0A494C0U8_A0A494C0U8_HUMAN:310:586_5v3m_C_1	5v3m	310-586	View model · PDB
Predicted = Low	TFS_tr_A0A494C0U8_A0A494C0U8_HUMAN:404:557_2i13_A_1	2i13	404-557	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
2	5v3m	199:590	310	586	P:C · DNA:A,B	59.6% / 71.8%	100	View · PDB TFS_tr_A0A494C0U8_A0A494C0U8_HUMAN:310:586_5v3m_C_1
3	5v3j	199:590	310	586	P:E · DNA:A,B	59.6% / 71.8%	100	View · PDB TFS_tr_A0A494C0U8_A0A494C0U8_HUMAN:310:586_5v3j_E_1
1	5wjq	199:590	252	530	P:D · DNA:A,B	57.7% / 74.9%	99	View · PDB TFS_tr_A0A494C0U8_A0A494C0U8_HUMAN:252:530_5wjq_D_1
4	2i13	199:590	404	557	P:A · DNA:C,D	55.8% / 70.8%	100	View · PDB TFS_tr_A0A494C0U8_A0A494C0U8_HUMAN:404:557_2i13_A_1
1	1llm	199:590	505,505	556,556	P:C,D · DNA:A,B	44.2% / 61.5%	59,61	View · PDB DIMER_tr_A0A494C0U8_A0A494C0U8_HUMAN:505:556_1llm_D_1
5	7w1m	199:590	255	553	P:H · DNA:F,G	34.1% / 49.7%	92	View · PDB TFS_tr_A0A494C0U8_A0A494C0U8_HUMAN:255:553_7w1m_H_1

Full sequence / unlocalized models18 models

Source	Model	Template	Residues modeled	Actions
Predicted = Low	a0a494c0u8.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a494c0u8.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a494c0u8.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a494c0u8.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a494c0u8.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a494c0u8.af3.5	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a494c0u8_dimer.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a494c0u8_dimer.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a494c0u8_dimer.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a494c0u8_dimer.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a494c0u8_dimer.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a494c0u8_dimer.af3.5	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a494c0u8_monomer.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a494c0u8_monomer.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a494c0u8_monomer.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a494c0u8_monomer.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a494c0u8_monomer.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a494c0u8_monomer.af3.5	-	Full sequence / not localized	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
36-77	PF01352	KRAB box	No overlap with loaded model regions
171-193	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
199-221	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
227-249	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
255-277	PF00096	Zinc finger, C2H2 type	overlaps 252-586
311-333	PF00096	Zinc finger, C2H2 type	overlaps 252-586
367-389	PF13912	C2H2-type zinc finger	overlaps 252-586
395-417	PF00096	Zinc finger, C2H2 type	overlaps 252-586
423-445	PF00096	Zinc finger, C2H2 type	overlaps 252-586
451-473	PF00096	Zinc finger, C2H2 type	overlaps 252-586
479-499	PF13912	C2H2-type zinc finger	overlaps 252-586
507-529	PF00096	Zinc finger, C2H2 type	overlaps 252-586
535-557	PF00096	Zinc finger, C2H2 type	overlaps 252-586
563-585	PF00096	Zinc finger, C2H2 type	overlaps 252-586