Transcription factor

A0A669KBJ7 - ADNP

Activity-dependent neuroprotector homeobox protein (Activity-dependent neuroprotective protein)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 1174 aa

16 Generated PWM 28 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE16

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
DIMER_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:881_3d1n_L_1	ModCRE	Homology model	GTAAACAATTTGGA	Region 843-881 · 1 3D model		Open · Scan
DIMER_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:882_1du0_A_1	ModCRE	Homology model	GCCAAGGAGGGCCCAC	Region 843-882 · 1 3D model		Open · Scan
DIMER_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:882_1hdd_D_1	ModCRE	Homology model	CGCCAGACGGGCCCCC	Region 843-882 · 1 3D model		Open · Scan
DIMER_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:882_2hdd_A_1	ModCRE	Homology model	CGCCAGGGGGGCGGGT	Region 843-882 · 1 3D model		Open · Scan
DIMER_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:882_3hdd_A_1	ModCRE	Homology model	GCCCAGGGGGGGGCCC	Region 843-882 · 1 3D model		Open · Scan
TFS_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:148:172_6df8_A_1	ModCRE	Homology model	GGCGAGAAAAA	Region 148-172 · 1 3D model		Open · Scan
TFS_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:148:172_6v8u_A_1	ModCRE	Homology model	TAACGGGCCC	Region 148-172 · 1 3D model		Open · Scan
TFS_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:511:545_6dfa_A_1	ModCRE	Homology model	CGCCTCGGCAGT	Region 511-545 · 1 3D model		Open · Scan
TFS_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:881_3d1n_L_1	ModCRE	Homology model	GTAAACAATTTGGA	Region 843-881 · 1 3D model		Open · Scan
TFS_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:882_1du0_A_1	ModCRE	Homology model	CCCAAGGAGGGCCCAC	Region 843-882 · 1 3D model		Open · Scan
a0a669kbj7.af3.0	ModCRE	AlphaFold3 model	CAATAGGGGCGACGTGCCGCCCCAACCGG	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a669kbj7.af3.1	ModCRE	AlphaFold3 model	CAATAGGGGCGACGTGTCGCCCCAACCGG	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a669kbj7.af3.2	ModCRE	AlphaFold3 model	ATAAAAAAATTTTTAGCCGAAAAATTTTTT	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a669kbj7.af3.3	ModCRE	AlphaFold3 model	TCAAAAGATGGCAGCCCGGTAATTAAATTA	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a669kbj7.af3.4	ModCRE	AlphaFold3 model	ATTTTCACAATTTTTAAAATATGTTTTTAA	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a669kbj7.af3.5	ModCRE	AlphaFold3 model	GGGGAACCCCGGGTAGGGGGCGCACCGTTT	AlphaFold3 model · ModCRE PWM		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 1174 aa

148-172

511-545

843-882

Region 148-172 2 PWM

Residues

25 aa

Domains

PF19627 · Activity-dependent neuroprotector homeobox protein N-terminal

3D models

2 active PDBs · 2 summary rows

Templates

6DF8, 6V8U

Sources

Predicted = Low

Scan this region Show models

Region 511-545 1 PWM

Residues

35 aa

Domains

PF26748 · Adnp2-like, C2H2-type zinc finger

3D models

1 active PDB · 1 summary row

Templates

6DFA

Sources

Predicted = Low

Scan this region Show models

Region 843-882 7 PWM

Residues

40 aa

Domains

PF00046 · Homeodomain

3D models

7 active PDBs · 7 summary rows

Templates

1DU0, 1HDD, 2HDD, 3D1N, 3HDD

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

28 active PDB models 10 summary rows

Region 148-1722 models · 2 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	TFS_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:148:172_6df8_A_1	6df8	148-172	View model · PDB
Predicted = Low	TFS_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:148:172_6v8u_A_1	6v8u	148-172	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
4	6df8	840:891	148	172	P:A · DNA:D,E	40.0% / 56.0%	21	View · PDB TFS_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:148:172_6df8_A_1
5	6v8u	840:891	148	172	P:A · DNA:D,E	40.0% / 56.0%	20	View · PDB TFS_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:148:172_6v8u_A_1

Region 511-5451 model · 1 summary row

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	TFS_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:511:545_6dfa_A_1	6dfa	511-545	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
3	6dfa	840:891	511	545	P:A · DNA:D,E	31.4% / 42.9%	29	View · PDB TFS_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:511:545_6dfa_A_1

Region 843-8827 models · 7 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:881_3d1n_L_1	3d1n	843-881	View model · PDB
Predicted = Low	DIMER_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:882_1du0_A_1	1du0	843-882	View model · PDB
Predicted = Low	DIMER_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:882_1hdd_D_1	1hdd	843-882	View model · PDB
Predicted = Low	DIMER_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:882_2hdd_A_1	2hdd	843-882	View model · PDB
Predicted = Low	DIMER_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:882_3hdd_A_1	3hdd	843-882	View model · PDB
Predicted = Low	TFS_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:881_3d1n_L_1	3d1n	843-881	View model · PDB
Predicted = Low	TFS_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:882_1du0_A_1	1du0	843-882	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
1	3d1n	840:891	843,843	881,881	P:K,L · DNA:C,D	38.5% / 56.4%	26,26	View · PDB DIMER_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:881_3d1n_L_1
1	3d1n	840:891	843,843	881,881	P:K,L · DNA:C,D	38.5% / 56.4%	26,26	View · PDB TFS_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:881_3d1n_L_1
2	1du0	840:891	843,843	882,882	P:A,B · DNA:C,D	37.5% / 60.0%	75,71	View · PDB DIMER_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:882_1du0_A_1
2	1du0	840:891	843,843	882,882	P:A,B · DNA:C,D	37.5% / 60.0%	75,71	View · PDB TFS_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:882_1du0_A_1
3	3hdd	840:891	843,843	882,882	P:A,B · DNA:C,D	37.5% / 57.5%	72,71	View · PDB DIMER_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:882_3hdd_A_1
4	2hdd	840:891	843,843	882,882	P:A,B · DNA:C,D	37.5% / 57.5%	72,71	View · PDB DIMER_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:882_2hdd_A_1
5	1hdd	840:891	843,843	882,882	P:C,D · DNA:A,B	37.5% / 57.5%	70,70	View · PDB DIMER_tr_A0A669KBJ7_A0A669KBJ7_HUMAN:843:882_1hdd_D_1

Full sequence / unlocalized models18 models

Source	Model	Template	Residues modeled	Actions
Predicted = Low	a0a669kbj7.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a669kbj7.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a669kbj7.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a669kbj7.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a669kbj7.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a669kbj7.af3.5	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a669kbj7_dimer.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a669kbj7_dimer.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a669kbj7_dimer.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a669kbj7_dimer.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a669kbj7_dimer.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a669kbj7_dimer.af3.5	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a669kbj7_monomer.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a669kbj7_monomer.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a669kbj7_monomer.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a669kbj7_monomer.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a669kbj7_monomer.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a669kbj7_monomer.af3.5	-	Full sequence / not localized	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
74-202	PF19627	Activity-dependent neuroprotector homeobox protein N-terminal	overlaps 148-172
518-542	PF26748	Adnp2-like, C2H2-type zinc finger	overlaps 511-545
841-882	PF00046	Homeodomain	overlaps 843-882