ModCRE DB

Transcription factor

A0A669KBK7 - ZNF648

Zinc finger protein 648

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 383 aa

28 Generated PWM 12 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)17
MotifPredictionSourceDNA bindingSupportLogoActions
M00939_2.00 NN 70-40% CisBP CCACCTCA 52.9% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 52.9% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 52.9% identity Open · Scan
M06179_2.00 NN 70-40% CisBP TAAGCCTATAGA 52.8% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 52.2% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 52.2% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 51.7% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 51.7% identity Open · Scan
M08255_2.00 NN 70-40% CisBP CTCTTCCGGT 51.5% identity Open · Scan
M03702_2.00 NN 70-40% CisBP GACCCCCCACGACGC 50.6% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 50.5% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 50.5% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 50.5% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 50.5% identity Open · Scan
MA0740.1 NN 70-40% JASPAR GGCCACGCCCCCTT 50.5% identity Open · Scan
M01456_2.00 NN 70-40% CisBP GTGATCGGCG 50.0% identity Open · Scan
M04590_2.00 NN 70-40% CisBP TGCGCTAACCATTGC 50.0% identity Open · Scan
ModCRE11
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_A0A669KBK7_A0A669KBK7_HUMAN:120:173_1llm_C_1 ModCRE Homology model TCCCGGCGGTTT Region 120-173 · 1 3D model Open · Scan
TFS_tr_A0A669KBK7_A0A669KBK7_HUMAN:159:313_2i13_A_1 ModCRE Homology model GCTAGCACTATACTAAGCCAG Region 159-313 · 1 3D model Open · Scan
TFS_tr_A0A669KBK7_A0A669KBK7_HUMAN:89:369_5wjq_D_1 ModCRE Homology model GTGCGCGGGGGGGGGGGGGGGCCCCCCC Region 89-369 · 1 3D model Open · Scan
TFS_tr_A0A669KBK7_A0A669KBK7_HUMAN:94:369_5v3j_E_1 ModCRE Homology model GAGGGACCCCGGGGGGGGTGCGTGGT Region 94-369 · 1 3D model Open · Scan
TFS_tr_A0A669KBK7_A0A669KBK7_HUMAN:94:369_5v3m_C_1 ModCRE Homology model CCTGGGTGGGGGGGGGGGGGGGGGCG Region 94-369 · 1 3D model Open · Scan
a0a669kbk7.af3.0 ModCRE AlphaFold3 model GGGGGGGGGGGGGCGCCGGGCTTTTTTA AlphaFold3 model · ModCRE PWM Open · Scan
a0a669kbk7.af3.1 ModCRE AlphaFold3 model GGGGGGGGGGGGGCGCCGGGCTTTTTTA AlphaFold3 model · ModCRE PWM Open · Scan
a0a669kbk7.af3.2 ModCRE AlphaFold3 model AGGGGGCCGCGGCCGCCGGGGGGGGGGGGG AlphaFold3 model · ModCRE PWM Open · Scan
a0a669kbk7.af3.3 ModCRE AlphaFold3 model CGGGGGCGGCGGCCCCGGGGGGGGGGGGGG AlphaFold3 model · ModCRE PWM Open · Scan
a0a669kbk7.af3.4 ModCRE AlphaFold3 model GCCACAGACCCCCCTCGGGCCCCCCCCCCC AlphaFold3 model · ModCRE PWM Open · Scan
a0a669kbk7.af3.5 ModCRE AlphaFold3 model CCCCCTCCCCCCCCCCGCCCCCCCCCCCCC AlphaFold3 model · ModCRE PWM Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 383 aa
89-369

Region 89-369 5 PWM

Residues
281 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
12 active PDB models 6 summary rows
Region 89-3696 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_A0A669KBK7_A0A669KBK7_HUMAN:120:173_1llm_C_1 1llm 120-173 View model · PDB
Predicted = Low TFS_tr_A0A669KBK7_A0A669KBK7_HUMAN:159:313_2i13_A_1 2i13 159-313 View model · PDB
Predicted = Low TFS_tr_A0A669KBK7_A0A669KBK7_HUMAN:89:369_5wjq_D_1 5wjq 89-369 View model · PDB
Predicted = Low TFS_tr_A0A669KBK7_A0A669KBK7_HUMAN:94:365_7w1m_H_1 7w1m 94-365 View model · PDB
Predicted = Low TFS_tr_A0A669KBK7_A0A669KBK7_HUMAN:94:369_5v3j_E_1 5v3j 94-369 View model · PDB
Predicted = Low TFS_tr_A0A669KBK7_A0A669KBK7_HUMAN:94:369_5v3m_C_1 5v3m 94-369 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
5 2i13 89:370 159 313 P:A · DNA:C,D 46.5% / 66.5% 100 View · PDB TFS_tr_A0A669KBK7_A0A669KBK7_HUMAN:159:313_2i13_A_1
1 5v3m 89:370 94 369 P:C · DNA:A,B 44.6% / 64.1% 99 View · PDB TFS_tr_A0A669KBK7_A0A669KBK7_HUMAN:94:369_5v3m_C_1
2 5v3j 89:370 94 369 P:E · DNA:A,B 44.6% / 64.1% 99 View · PDB TFS_tr_A0A669KBK7_A0A669KBK7_HUMAN:94:369_5v3j_E_1
3 5wjq 89:370 89 369 P:D · DNA:A,B 42.7% / 61.2% 99 View · PDB TFS_tr_A0A669KBK7_A0A669KBK7_HUMAN:89:369_5wjq_D_1
1 1llm 89:370 120,120 173,173 P:C,D · DNA:A,B 42.6% / 63.0% 62,63 View · PDB DIMER_tr_A0A669KBK7_A0A669KBK7_HUMAN:120:173_1llm_C_1
4 7w1m 89:370 94 365 P:H · DNA:F,G 36.2% / 48.9% 84 View · PDB TFS_tr_A0A669KBK7_A0A669KBK7_HUMAN:94:365_7w1m_H_1
Full sequence / unlocalized models6 models
SourceModelTemplateResidues modeledActions
Predicted = Lowa0a669kbk7.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a669kbk7.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a669kbk7.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a669kbk7.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a669kbk7.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a669kbk7.af3.5-Full sequence / not localizedView model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
94-116PF00096Zinc finger, C2H2 typeoverlaps 89-369
150-173PF00096Zinc finger, C2H2 typeoverlaps 89-369
179-201PF00096Zinc finger, C2H2 typeoverlaps 89-369
235-257PF00096Zinc finger, C2H2 typeoverlaps 89-369
263-285PF00096Zinc finger, C2H2 typeoverlaps 89-369
291-313PF00096Zinc finger, C2H2 typeoverlaps 89-369
319-341PF00096Zinc finger, C2H2 typeoverlaps 89-369
347-369PF00096Zinc finger, C2H2 typeoverlaps 89-369