ModCRE DB

Transcription factor

A0A679EM68 - ESR1

Estrogen receptor (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 292 aa

86 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)5
MotifPredictionSourceDNA bindingSupportLogoActions
MA0112.1 NN 70+% JASPAR CCAGGTCACCGTGACCCC 99.6% identity Open · Scan
MA0258.1 NN 70+% JASPAR CAAGGTCACGGTGACCTG 87.0% identity Open · Scan
M09309_2.00 NN 70+% CisBP AGGTCAGGGTGACCT 86.8% identity Open · Scan
M09296_2.00 NN 70+% CisBP TCAAGGTCA 70.8% identity Open · Scan
MA0643.1 NN 70+% JASPAR TCAAGGTCAT 70.8% identity Open · Scan
Nearest Neighbor (70% - 40%)81
MotifPredictionSourceDNA bindingSupportLogoActions
MA0592.1 NN 70-40% JASPAR CCAAGGTCACA 68.0% identity Open · Scan
MA0592.2 NN 70-40% JASPAR TTCAAGGTCAT 68.0% identity Open · Scan
MA0141.1 NN 70-40% JASPAR AGCTCAAGGTCA 67.0% identity Open · Scan
MA0141.3 NN 70-40% JASPAR TCAAGGTCATA 67.0% identity Open · Scan
MA0859.1 NN 70-40% JASPAR AAGGTCAAAAGGTCAA 61.7% identity Open · Scan
MA1553.1 NN 70-40% JASPAR AAGGTCATGACCTT 61.7% identity Open · Scan
M09275_2.00 NN 70-40% CisBP GGGTCACTTCAGGTCAG 60.0% identity Open · Scan
M03424_2.00 NN 70-40% CisBP AAAGGTCACCAGAGGTCA 58.8% identity Open · Scan
M05563_2.00 NN 70-40% CisBP AAAAGGTCAA 58.8% identity Open · Scan
MA0159.1 NN 70-40% JASPAR AGGTCACGGAGAGGTCA 58.8% identity Open · Scan
MA0857.1 NN 70-40% JASPAR AAAGGTCAAAAGGTCA 58.8% identity Open · Scan
MA1552.1 NN 70-40% JASPAR AAGGTCATGACCTT 58.8% identity Open · Scan
M00371_2.00 NN 70-40% CisBP ACTTAATATATAC 58.3% identity Open · Scan
MA0007.1 NN 70-40% JASPAR ATAAGAACACCCTGTACCCGCC 57.9% identity Open · Scan
MA0007.3 NN 70-40% JASPAR GGGAACACGGTGTACCC 57.9% identity Open · Scan
M00811_2.00 NN 70-40% CisBP AAAGGTCAAG 57.6% identity Open · Scan
M03432_2.00 NN 70-40% CisBP AAAGGTCAAGAGAGGTCA 57.3% identity Open · Scan
M06417_2.00 NN 70-40% CisBP CAGTCCGAAGGTCACCGC 56.0% identity Open · Scan
M05886_2.00 NN 70-40% CisBP AGTACATTTTGTTCT 55.8% identity Open · Scan
M07987_2.00 NN 70-40% CisBP GCCCAGAACATTCTGTTCCCT 55.8% identity Open · Scan
MA0113.1 NN 70-40% JASPAR GGGAACATTATGTCCTAA 55.8% identity Open · Scan
MA0677.1 NN 70-40% JASPAR GAGGTCAAAGGTCA 55.8% identity Open · Scan
MA1539.1 NN 70-40% JASPAR AAGGTCACTGACCTT 55.8% identity Open · Scan
M00822_2.00 NN 70-40% CisBP GAGGTCAC 54.5% identity Open · Scan
M02393_2.00 NN 70-40% CisBP AGAGGTCAC 54.5% identity Open · Scan
M02400_2.00 NN 70-40% CisBP GGGGTCAC 54.5% identity Open · Scan
M05661_2.00 NN 70-40% CisBP GGGGTCAAAGGTCAG 54.5% identity Open · Scan
MA0017.1 NN 70-40% JASPAR TGACCTTTGAACCT 54.5% identity Open · Scan
MA0071.1 NN 70-40% JASPAR ATCAAGGTCA 54.5% identity Open · Scan
MA0856.1 NN 70-40% JASPAR GGGGTCAAAGGTCA 54.5% identity Open · Scan
MA1111.1 NN 70-40% JASPAR CAAAGGTCAAA 54.5% identity Open · Scan
M03435_2.00 NN 70-40% CisBP GGGGTCAAAGGTCA 54.4% identity Open · Scan
MA0115.1 NN 70-40% JASPAR AAAGGTCAAAGGTCAAC 54.4% identity Open · Scan
MA0855.1 NN 70-40% JASPAR GGGGTCAAAGGTCA 54.4% identity Open · Scan
M00814_2.00 NN 70-40% CisBP AAAGTCAAAT 54.2% identity Open · Scan
M01298_2.00 NN 70-40% CisBP AAAGGTCA 54.2% identity Open · Scan
M02408_2.00 NN 70-40% CisBP TGAGGTCAATTT 54.2% identity Open · Scan
MA0676.1 NN 70-40% JASPAR AAAAGTCAA 54.2% identity Open · Scan
M05604_2.00 NN 70-40% CisBP TAAAGGTCAC 53.9% identity Open · Scan
MA1112.1 NN 70-40% JASPAR AAAAGGTCAC 53.9% identity Open · Scan
M05660_2.00 NN 70-40% CisBP GATGTGGGTCAGTGGGTCAG 53.7% identity Open · Scan
MA1531.1 NN 70-40% JASPAR GGGTCAGTAGGTCAG 53.7% identity Open · Scan
MA1532.1 NN 70-40% JASPAR GGGTTAGTGGGTCAT 53.7% identity Open · Scan
M02392_2.00 NN 70-40% CisBP GAGGTCAA 53.1% identity Open · Scan
M00820_2.00 NN 70-40% CisBP TAGGTCACC 53.0% identity Open · Scan
M02388_2.00 NN 70-40% CisBP GAGGTCA 53.0% identity Open · Scan
M03421_2.00 NN 70-40% CisBP GGGGTCAAAGGTCA 53.0% identity Open · Scan
M05590_2.00 NN 70-40% CisBP TTCAAGGTCAC 53.0% identity Open · Scan
M09616_2.00 NN 70-40% CisBP TTCAAGGTCA 53.0% identity Open · Scan
M11139_2.00 NN 70-40% CisBP AAGTAGGTCACCGTGACCTACTT 53.0% identity Open · Scan
M11192_2.00 NN 70-40% CisBP GGGGTCACG 53.0% identity Open · Scan
MA0065.1 NN 70-40% JASPAR CCAGGGGTCAAAGGTCATCG 53.0% identity Open · Scan
MA0065.2 NN 70-40% JASPAR GTAGGGCAAAGGTCA 53.0% identity Open · Scan
MA0494.1 NN 70-40% JASPAR TGACCTAAAGTAACCTCTG 53.0% identity Open · Scan
MA0505.1 NN 70-40% JASPAR AAGTTCAAGGTCAGC 53.0% identity Open · Scan
MA1150.1 NN 70-40% JASPAR AATTAGGTCAC 53.0% identity Open · Scan
MA1540.1 NN 70-40% JASPAR GTCAAGGTCAC 53.0% identity Open · Scan
M03927_2.00 NN 70-40% CisBP GAAACTAGAGCA 52.9% identity Open · Scan
M09277_2.00 NN 70-40% CisBP GGGGGATCAAGAGGTCAAGG 52.9% identity Open · Scan
MA0484.1 NN 70-40% JASPAR AGAGTCCAAAGTCCA 52.9% identity Open · Scan
MA1574.1 NN 70-40% JASPAR GGGGTCAAAGGTCAT 52.9% identity Open · Scan
MA0160.1 NN 70-40% JASPAR AAGGTCAC 52.6% identity Open · Scan
M02409_2.00 NN 70-40% CisBP GAGATCAA 52.1% identity Open · Scan
M06432_2.00 NN 70-40% CisBP AAAAATCAAAGGT 52.1% identity Open · Scan
M03392_2.00 NN 70-40% CisBP AAGGTCAACTAAAGGTCA 52.0% identity Open · Scan
MA1110.1 NN 70-40% JASPAR TCAATGACCTA 51.9% identity Open · Scan
M05635_2.00 NN 70-40% CisBP GTGACCTCAATGAGGTCAC 51.7% identity Open · Scan
MA1148.1 NN 70-40% JASPAR ATGTAGGTCAAAGGTCAT 51.5% identity Open · Scan
M09283_2.00 NN 70-40% CisBP TGAGGTCAAAAAAGTTCAG 50.7% identity Open · Scan
MA1533.1 NN 70-40% JASPAR ATGAACTCGATGAACTC 50.7% identity Open · Scan
M03923_2.00 NN 70-40% CisBP AGAACACTGTGTACC 50.6% identity Open · Scan
M03939_2.00 NN 70-40% CisBP TAAAGGTCA 50.6% identity Open · Scan
M00686_2.00 NN 70-40% CisBP AGTGATCA 50.0% identity Open · Scan
M00690_2.00 NN 70-40% CisBP AAAGATCAAA 50.0% identity Open · Scan
M02405_2.00 NN 70-40% CisBP AGAGGTCAGT 50.0% identity Open · Scan
M02413_2.00 NN 70-40% CisBP CGAGATCAA 50.0% identity Open · Scan
M03426_2.00 NN 70-40% CisBP GGGGTCAAAGTCCAAT 50.0% identity Open · Scan
M03928_2.00 NN 70-40% CisBP ATGTAGGTCAAG 50.0% identity Open · Scan
M06413_2.00 NN 70-40% CisBP AAATAGGTCA 50.0% identity Open · Scan
M06431_2.00 NN 70-40% CisBP AAAAGTCAAA 50.0% identity Open · Scan
MA1151.1 NN 70-40% JASPAR ATAAGTAGGTCA 50.0% identity Open · Scan
ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 292 aa
180-252

Region 180-252 0 PWM

Residues
73 aa
Domains
PF02159 · Oestrogen receptor PF00105 · Double treble clef zinc finger, C4 type
3D models
1 active PDB
Templates
1HCQ
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 180-2521 model
Actions
Predicted = Low DIMER_A0A679EM68:180:252_1hcq_A_1 1hcq 180-252 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
42-181PF02159Oestrogen receptoroverlaps 180-252
184-252PF00105Double treble clef zinc finger, C4 typeoverlaps 180-252