ModCRE DB

Transcription factor

A0A6Q8PH34 - ZEB2

Zinc finger E-box binding homeobox 2

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 391 aa

43 Generated PWM 17 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)32
MotifPredictionSourceDNA bindingSupportLogoActions
M08860_2.00 NN 70-40% CisBP TCTTATAAGGGCACTAATCCCATT 55.8% identity Open · Scan
MA0103.2 NN 70-40% JASPAR CCTCACCTG 54.5% identity Open · Scan
M08267_2.00 NN 70-40% CisBP CAGTTTCATTTTCC 53.7% identity Open · Scan
M08335_2.00 NN 70-40% CisBP AGTCGTTGTCTG 53.6% identity Open · Scan
M06179_2.00 NN 70-40% CisBP TAAGCCTATAGA 53.4% identity Open · Scan
MA1587.1 NN 70-40% JASPAR CCTCGACCTCCTGA 53.3% identity Open · Scan
MA0103.1 NN 70-40% JASPAR CACCTG 53.1% identity Open · Scan
M07753_2.00 NN 70-40% CisBP TGCATTCCTTGGCTTGTG 52.7% identity Open · Scan
M08311_2.00 NN 70-40% CisBP CTGGAACAGAAGGGGCGA 52.2% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 52.1% identity Open · Scan
M07684_2.00 NN 70-40% CisBP CCTGTTCTTGACTTT 52.1% identity Open · Scan
M07566_2.00 NN 70-40% CisBP TCAAACCATCCTTGC 52.0% identity Open · Scan
M08390_2.00 NN 70-40% CisBP GCTTTGTTGACTCAC 51.5% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 51.4% identity Open · Scan
M05844_2.00 NN 70-40% CisBP TCACCTGT 51.4% identity Open · Scan
M07601_2.00 NN 70-40% CisBP CAGATGCCGGCACCATGCTTC 51.4% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 51.3% identity Open · Scan
M08347_2.00 NN 70-40% CisBP GCCCTGGGCAGC 51.3% identity Open · Scan
M08300_2.00 NN 70-40% CisBP CTGCCCAATTCAT 51.2% identity Open · Scan
M07667_2.00 NN 70-40% CisBP CCGCACAGGCCCCCGGGCCCC 50.7% identity Open · Scan
M08252_2.00 NN 70-40% CisBP CCGGCTCCAGCACCC 50.7% identity Open · Scan
M04475_2.00 NN 70-40% CisBP GATGCACGTACCGTGCCTCA 50.6% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 50.6% identity Open · Scan
M07590_2.00 NN 70-40% CisBP TTTTTTTCTTTTATTTTTTTTTTTTTTTTTTTT 50.6% identity Open · Scan
M01473_2.00 NN 70-40% CisBP AGCGCGCCGA 50.0% identity Open · Scan
M01883_2.00 NN 70-40% CisBP TGCCCCTGA 50.0% identity Open · Scan
M07567_2.00 NN 70-40% CisBP CCACTCCACTCA 50.0% identity Open · Scan
M07703_2.00 NN 70-40% CisBP CCGACGG 50.0% identity Open · Scan
M08373_2.00 NN 70-40% CisBP CCCCCTGGCTCTTCCTCT 50.0% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 50.0% identity Open · Scan
MA0038.1 NN 70-40% JASPAR CAAATCACTG 50.0% identity Open · Scan
MA0038.2 NN 70-40% JASPAR CAAATCACTGCA 50.0% identity Open · Scan
ModCRE11
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:176:227_1f2i_G_1 ModCRE Homology model GGGTAATTACC Region 176-227 · 1 3D model Open · Scan
TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:176:227_1f2i_H_1 ModCRE Homology model AGGAACTACCA Region 176-227 · 1 3D model Open · Scan
TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:176:229_4gzn_C_1 ModCRE Homology model CCCTGGCCCC Region 176-229 · 1 3D model Open · Scan
TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:176:229_4m9v_C_1 ModCRE Homology model CCTCAGCCCC Region 176-229 · 1 3D model Open · Scan
TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:181:255_5keb_A_1 ModCRE Homology model GGTGGCGGGC Region 181-255 · 1 3D model Open · Scan
a0a6q8ph34.af3.0 ModCRE AlphaFold3 model GACCTCGGGGGCGGCCGG AlphaFold3 model · ModCRE PWM Open · Scan
a0a6q8ph34.af3.1 ModCRE AlphaFold3 model GGGGCCCCCCCAGGGGT AlphaFold3 model · ModCRE PWM Open · Scan
a0a6q8ph34.af3.2 ModCRE AlphaFold3 model GGGGGCGCCCCCGAGGGC AlphaFold3 model · ModCRE PWM Open · Scan
a0a6q8ph34.af3.3 ModCRE AlphaFold3 model CCCCCAGGGGAACCCCCC AlphaFold3 model · ModCRE PWM Open · Scan
a0a6q8ph34.af3.4 ModCRE AlphaFold3 model GACCTCGGGGGCGGCCGG AlphaFold3 model · ModCRE PWM Open · Scan
a0a6q8ph34.af3.5 ModCRE AlphaFold3 model GCCCAGGGGGGAGCCCG AlphaFold3 model · ModCRE PWM Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 391 aa
176-255

Region 176-255 5 PWM

Residues
80 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
11 active PDBs · 6 summary rows
Templates
1A1F, 1A1G, 1A1H, 1A1J, 1A1K, 1F2I, 1LLM, 4GZN, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
17 active PDB models 6 summary rows
Region 176-25511 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:202:250_1llm_C_1 1llm 202-250 View model · PDB
Predicted = Low TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:176:227_1f2i_G_1 1f2i 176-227 View model · PDB
Predicted = Low TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:176:227_1f2i_H_1 1f2i 176-227 View model · PDB
Predicted = Low TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:176:229_4gzn_C_1 4gzn 176-229 View model · PDB
Predicted = Low TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:176:229_4m9v_C_1 4m9v 176-229 View model · PDB
Predicted = Low TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:176:250_1a1f_A_1 1a1f 176-250 View model · PDB
Predicted = Low TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:176:250_1a1g_A_1 1a1g 176-250 View model · PDB
Predicted = Low TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:176:250_1a1h_A_1 1a1h 176-250 View model · PDB
Predicted = Low TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:176:250_1a1j_A_1 1a1j 176-250 View model · PDB
Predicted = Low TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:176:250_1a1k_A_1 1a1k 176-250 View model · PDB
Predicted = Low TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:181:255_5keb_A_1 5keb 181-255 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 1a1h 159:256 176 250 P:A · DNA:B,C 46.8% / 63.6% 88 View · PDB TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:176:250_1a1h_A_1
2 1a1g 159:256 176 250 P:A · DNA:B,C 46.8% / 63.6% 89 View · PDB TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:176:250_1a1g_A_1
3 1a1f 159:256 176 250 P:A · DNA:B,C 46.8% / 63.6% 89 View · PDB TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:176:250_1a1f_A_1
4 1a1j 159:256 176 250 P:A · DNA:B,C 45.5% / 63.6% 89 View · PDB TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:176:250_1a1j_A_1
5 1a1k 159:256 176 250 P:A · DNA:B,C 45.5% / 63.6% 88 View · PDB TFS_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:176:250_1a1k_A_1
1 1llm 159:256 202,202 250,250 P:C,D · DNA:A,B 44.9% / 63.3% 56,57 View · PDB DIMER_tr_A0A6Q8PH34_A0A6Q8PH34_HUMAN:202:250_1llm_C_1
Full sequence / unlocalized models6 models
SourceModelTemplateResidues modeledActions
Predicted = Lowa0a6q8ph34.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a6q8ph34.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a6q8ph34.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a6q8ph34.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a6q8ph34.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a6q8ph34.af3.5-Full sequence / not localizedView model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
176-198PF00096Zinc finger, C2H2 typeoverlaps 176-255
232-252PF00096Zinc finger, C2H2 typeoverlaps 176-255