Transcription factor

A0A7I2V395 - STAT3

Signal transducer and activator of transcription

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 721 aa

1 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M08043_2.00	Known	CisBP	CTTCCTGGAAG	Direct PWM		Open · Scan

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 721 aa

269-690

Residues: 422 aa
Domains: PF01017 · STAT transcription factor, coiled-coil domain PF02864 · STAT protein, DNA binding domain PF21354 · Signal transducer and activator of transcription, linker domain PF00017 · SH2 domain
3D models: 1 active PDB
Templates: 4Y5W
Sources: Structure model

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

1 active PDB model

Region 269-6901 model

				Actions
Predicted = Low	DIMER_A0A7I2V395:269:690_4y5w_A_1	4y5w	269-690	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
2-119	PF02865	STAT protein, protein interaction domain	No overlap with loaded model regions
145-313	PF01017	STAT transcription factor, coiled-coil domain	overlaps 269-690
326-464	PF02864	STAT protein, DNA binding domain	overlaps 269-690
488-565	PF21354	Signal transducer and activator of transcription, linker domain	overlaps 269-690
584-651	PF00017	SH2 domain	overlaps 269-690