Transcription factor

A0A7I2V4C8 - STAT3

Signal transducer and activator of transcription

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 742 aa

5 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)3

Motif	Prediction	Source	DNA binding	Support	Actions
MA0144.2	NN 70+%	JASPAR	CTTCTGGGAAA	96.3% identity	Open · Scan
MA0144.1	NN 70+%	JASPAR	TTCCAGGAAG	96.2% identity	Open · Scan
M08043_2.00	NN 70+%	CisBP	CTTCCTGGAAG	96.1% identity	Open · Scan

Nearest Neighbor (70% - 40%)2

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M08014_2.00	NN 70-40%	CisBP	TTTCCCGGAAA	51.4% identity		Open · Scan
MA0137.3	NN 70-40%	JASPAR	TTTCCAGGAAA	50.7% identity		Open · Scan

ModCRE0

No generated PWM in this category.

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 742 aa

430-662

Residues: 233 aa
Domains: PF21354 · Signal transducer and activator of transcription, linker domain PF00017 · SH2 domain
3D models: 1 active PDB
Templates: 4Y5W
Sources: Structure model

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

1 active PDB model

Region 430-6621 model

				Actions
Predicted = Low	DIMER_A0A7I2V4C8:430:662_4y5w_A_1	4y5w	430-662	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
2-119	PF02865	STAT protein, protein interaction domain	No overlap with loaded model regions
145-313	PF01017	STAT transcription factor, coiled-coil domain	No overlap with loaded model regions
326-421	PF02864	STAT protein, DNA binding domain	No overlap with loaded model regions
460-537	PF21354	Signal transducer and activator of transcription, linker domain	overlaps 430-662
556-623	PF00017	SH2 domain	overlaps 430-662