ModCRE DB

Transcription factor

A0A7I2V552 - STAT3

Signal transducer and activator of transcription

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 737 aa

5 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)3
MotifPredictionSourceDNA bindingSupportLogoActions
M08043_2.00 NN 70+% CisBP CTTCCTGGAAG 95.7% identity Open · Scan
MA0144.2 NN 70+% JASPAR CTTCTGGGAAA 95.7% identity Open · Scan
MA0144.1 NN 70+% JASPAR TTCCAGGAAG 95.5% identity Open · Scan
Nearest Neighbor (70% - 40%)2
MotifPredictionSourceDNA bindingSupportLogoActions
M08014_2.00 NN 70-40% CisBP TTTCCCGGAAA 53.0% identity Open · Scan
MA0137.3 NN 70-40% JASPAR TTTCCAGGAAA 52.3% identity Open · Scan
ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 737 aa
237-658

Region 237-658 0 PWM

Residues
422 aa
Domains
PF01017 · STAT transcription factor, coiled-coil domain PF02864 · STAT protein, DNA binding domain PF21354 · Signal transducer and activator of transcription, linker domain PF00017 · SH2 domain
3D models
1 active PDB
Templates
4Y5W
Sources
Structure model
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 237-6581 model
Actions
Predicted = Low DIMER_A0A7I2V552:237:658_4y5w_A_1 4y5w 237-658 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
117-281PF01017STAT transcription factor, coiled-coil domainoverlaps 237-658
294-432PF02864STAT protein, DNA binding domainoverlaps 237-658
456-533PF21354Signal transducer and activator of transcription, linker domainoverlaps 237-658
552-619PF00017SH2 domainoverlaps 237-658