ModCRE DB

Transcription factor

A0A7I2YQD2 - STAT3

Signal transducer and activator of transcription

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 726 aa

6 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)3
MotifPredictionSourceDNA bindingSupportLogoActions
M08043_2.00 NN 70+% CisBP CTTCCTGGAAG 99.1% identity Open · Scan
MA0144.1 NN 70+% JASPAR TTCCAGGAAG 99.0% identity Open · Scan
MA0144.2 NN 70+% JASPAR CTTCTGGGAAA 99.0% identity Open · Scan
Nearest Neighbor (70% - 40%)3
MotifPredictionSourceDNA bindingSupportLogoActions
M08014_2.00 NN 70-40% CisBP TTTCCCGGAAA 53.1% identity Open · Scan
MA0137.3 NN 70-40% JASPAR TTTCCAGGAAA 53.1% identity Open · Scan
M11361_2.00 NN 70-40% CisBP GATTTCCA 50.2% identity Open · Scan
ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 726 aa
269-695

Region 269-695 0 PWM

Residues
427 aa
Domains
PF01017 · STAT transcription factor, coiled-coil domain PF02864 · STAT protein, DNA binding domain PF21354 · Signal transducer and activator of transcription, linker domain PF00017 · SH2 domain
3D models
1 active PDB
Templates
4Y5W
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 269-6951 model
Actions
Predicted = Low DIMER_A0A7I2YQD2:269:695_4y5w_A_1 4y5w 269-695 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
2-119PF02865STAT protein, protein interaction domainNo overlap with loaded model regions
145-313PF01017STAT transcription factor, coiled-coil domainoverlaps 269-695
326-469PF02864STAT protein, DNA binding domainoverlaps 269-695
493-570PF21354Signal transducer and activator of transcription, linker domainoverlaps 269-695
589-656PF00017SH2 domainoverlaps 269-695