ModCRE DB

Transcription factor

A0A7P0TA87 - NPAS3

Neuronal PAS domain protein 3

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 108 aa

14 Generated PWM 10 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)4
MotifPredictionSourceDNA bindingSupportLogoActions
M09455_2.00 NN 70-40% CisBP GCACGTACCC 68.6% identity Open · Scan
M08713_2.00 NN 70-40% CisBP GGACGTGC 66.6% identity Open · Scan
MA0259.1 NN 70-40% JASPAR GGACGTGC 66.6% identity Open · Scan
M06462_2.00 NN 70-40% CisBP GTACGTGAC 58.1% identity Open · Scan
ModCRE10
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:12:55_5gnj_G_1 ModCRE Homology model TGCCACCGTGTGG Region 12-55 · 1 3D model Open · Scan
DIMER_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:27:63_1am9_A_1 ModCRE Homology model CCGCCCCACGGGGGCCCCCAGGGCGCGCGGGGGCCCC Region 27-63 · 1 3D model Open · Scan
DIMER_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:27:63_1am9_B_1 ModCRE Homology model CCCCACCCACGGGGGCCTCACAGCCCCCGCGGTGTGG Region 27-63 · 1 3D model Open · Scan
DIMER_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:27:63_1am9_D_1 ModCRE Homology model GGTGCCCCCCGGGTGCATCTGAGT Region 27-63 · 1 3D model Open · Scan
DIMER_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:7:55_8osl_N_1 ModCRE Homology model ACAGGCGCCTCTCGCAGCGCAACAAAGAACGACCAAAACCAGCCGATAACCGTTGCCAAGCAGACCTCGTAGATATCCCGGACACATGGCGGACCACCCCCCT Region 7-55 · 1 3D model Open · Scan
TFS_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:14:60_5nj8_A_1 ModCRE Homology model GCTGGTGTGACA Region 14-60 · 1 3D model Open · Scan
TFS_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:18:60_5v0l_B_1 ModCRE Homology model TTTGTGTGTCA Region 18-60 · 1 3D model Open · Scan
TFS_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:5:56_4zpk_B_1 ModCRE Homology model GCGCGTACGCGCGCG Region 5-56 · 1 3D model Open · Scan
TFS_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:6:108_5sy7_B_1 ModCRE Homology model GCCCCCGCGTGGGCAACC Region 6-108 · 1 3D model Open · Scan
TFS_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:6:58_4zpr_B_1 ModCRE Homology model GCGCGTACCGGCCGGGG Region 6-58 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 108 aa
5-108

Region 5-108 10 PWM

Residues
104 aa
Domains
PF23171 · Hypoxia-inducible factor 1-alpha bHLH domain
3D models
10 active PDBs · 10 summary rows
Templates
1AM9, 4ZPK, 4ZPR, 5GNJ, 5NJ8, 5SY7, 5V0L, 8OSL
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
10 active PDB models 10 summary rows
Region 5-10810 models · 10 summary rows
Actions
Predicted = Low DIMER_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:12:55_5gnj_G_1 5gnj 12-55 View model · PDB
Predicted = Low DIMER_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:27:63_1am9_A_1 1am9 27-63 View model · PDB
Predicted = Low DIMER_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:27:63_1am9_B_1 1am9 27-63 View model · PDB
Predicted = Low DIMER_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:27:63_1am9_D_1 1am9 27-63 View model · PDB
Predicted = Low DIMER_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:7:55_8osl_N_1 8osl 7-55 View model · PDB
Predicted = Low TFS_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:14:60_5nj8_A_1 5nj8 14-60 View model · PDB
Predicted = Low TFS_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:18:60_5v0l_B_1 5v0l 18-60 View model · PDB
Predicted = Low TFS_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:5:56_4zpk_B_1 4zpk 5-56 View model · PDB
Predicted = Low TFS_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:6:108_5sy7_B_1 5sy7 6-108 View model · PDB
Predicted = Low TFS_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:6:58_4zpr_B_1 4zpr 6-58 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5sy7 5:108 6 108 P:B · DNA:C,D 71.8% / 71.8% 26 View · PDB TFS_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:6:108_5sy7_B_1
2 4zpr 5:108 6 58 P:B · DNA:C,D 71.7% / 84.9% 18 View · PDB TFS_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:6:58_4zpr_B_1
3 4zpk 5:108 5 56 P:B · DNA:C,D 69.2% / 80.8% 16 View · PDB TFS_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:5:56_4zpk_B_1
5 5v0l 5:108 18 60 P:B · DNA:C,D 44.2% / 67.4% 25 View · PDB TFS_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:18:60_5v0l_B_1
4 5nj8 5:108 14 60 P:A · DNA:E,F 40.4% / 66.0% 26 View · PDB TFS_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:14:60_5nj8_A_1
2 5gnj 5:108 12,12 55,55 P:G,I · DNA:K,L 38.6% / 59.1% 54,53 View · PDB DIMER_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:12:55_5gnj_G_1
1 8osl 5:108 7,7 55,55 P:N,P · DNA:I,J 30.6% / 57.1% 16,98 View · PDB DIMER_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:7:55_8osl_N_1
3 1am9 5:108 27,27 63,63 P:C,D · DNA:E,F,G,H 24.3% / 59.5% 45,48 View · PDB DIMER_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:27:63_1am9_D_1
4 1am9 5:108 27,27 63,63 P:B,D · DNA:E,F,G,H 24.3% / 59.5% 49,48 View · PDB DIMER_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:27:63_1am9_B_1
5 1am9 5:108 27,27 63,63 P:A,D · DNA:E,F,G,H 24.3% / 59.5% 46,48 View · PDB DIMER_tr_A0A7P0TA87_A0A7P0TA87_HUMAN:27:63_1am9_A_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
6-65PF23171Hypoxia-inducible factor 1-alpha bHLH domainoverlaps 5-108