ModCRE DB

Transcription factor

A0A8I5KTU3 - MITF

Melanocyte inducing transcription factor

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 495 aa

7 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)3
MotifPredictionSourceDNA bindingSupportLogoActions
MA0620.2 NN 70+% JASPAR TAAGGTCACGTGACCTTA 94.1% identity Open · Scan
MA0620.1 NN 70+% JASPAR GGTCACGTGG 88.9% identity Open · Scan
M09475_2.00 NN 70+% CisBP GTCACATGAC 88.3% identity Open · Scan
Nearest Neighbor (70% - 40%)4
MotifPredictionSourceDNA bindingSupportLogoActions
M06003_2.00 NN 70-40% CisBP TCACGTG 62.6% identity Open · Scan
MA0871.1 NN 70-40% JASPAR ATCACGTGAC 58.3% identity Open · Scan
M01736_2.00 NN 70-40% CisBP CCACGTGACC 55.0% identity Open · Scan
M01762_2.00 NN 70-40% CisBP ATCACGTGAT 54.5% identity Open · Scan
ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 495 aa
277-362

Region 277-362 0 PWM

Residues
86 aa
Domains
PF00010 · Helix-loop-helix DNA-binding domain
3D models
1 active PDB
Templates
5I50
Sources
Structure model
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 277-3621 model
Actions
Predicted = Low DIMER_A0A8I5KTU3:277:362_5i50_B_1 5i50 277-362 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
56-138PF15951MITF/TFEB/TFEC/TFE3 N-terminusNo overlap with loaded model regions
281-334PF00010Helix-loop-helix DNA-binding domainoverlaps 277-362
366-490PF11851Domain of unknown function (DUF3371)No overlap with loaded model regions