ModCRE DB

Transcription factor

A0A8I5KWX0 - ZIM2

Zinc finger imprinted 2

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 558 aa

15 Generated PWM 12 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)3
MotifPredictionSourceDNA bindingSupportLogoActions
M08908_2.00 NN 70-40% CisBP GCTGCTGCTTCTGCTG 52.6% identity Open · Scan
M01439_2.00 NN 70-40% CisBP TTACGCCACA 51.1% identity Open · Scan
M08955_2.00 NN 70-40% CisBP GATCCTCCCGCCTCAGCCTCCC 50.0% identity Open · Scan
ModCRE12
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_A0A8I5KWX0_A0A8I5KWX0_HUMAN:498:543_1llm_D_1 ModCRE Homology model CCGCGCGCGAAA Region 498-543 · 1 3D model Open · Scan
TFS_tr_A0A8I5KWX0_A0A8I5KWX0_HUMAN:359:558_5v3j_E_1 ModCRE Homology model TCGAGGAAACCCCTTTTA Region 359-558 · 1 3D model Open · Scan
TFS_tr_A0A8I5KWX0_A0A8I5KWX0_HUMAN:359:558_5v3m_C_1 ModCRE Homology model GCGGGATGATCCCCAATTG Region 359-558 · 1 3D model Open · Scan
TFS_tr_A0A8I5KWX0_A0A8I5KWX0_HUMAN:361:465_5ei9_E_1 ModCRE Homology model CCCCTGGTACCACCCCC Region 361-465 · 1 3D model Open · Scan
TFS_tr_A0A8I5KWX0_A0A8I5KWX0_HUMAN:361:548_5wjq_D_1 ModCRE Homology model GTGCCCCCCCCAGCCCTTGCCCCGCCG Region 361-548 · 1 3D model Open · Scan
TFS_tr_A0A8I5KWX0_A0A8I5KWX0_HUMAN:368:519_2i13_A_1 ModCRE Homology model GATATACATGCGGTTCTTTTT Region 368-519 · 1 3D model Open · Scan
a0a8i5kwx0.af3.0 ModCRE AlphaFold3 model CCACACGACGTGGGACGTACTTCATA AlphaFold3 model · ModCRE PWM Open · Scan
a0a8i5kwx0.af3.1 ModCRE AlphaFold3 model CGCATGGGCATATCCGCTCGC AlphaFold3 model · ModCRE PWM Open · Scan
a0a8i5kwx0.af3.2 ModCRE AlphaFold3 model AGCTGTGAACTGCATAATGGGCAAA AlphaFold3 model · ModCRE PWM Open · Scan
a0a8i5kwx0.af3.3 ModCRE AlphaFold3 model CCACACGACGTGGGACGTACTTCATA AlphaFold3 model · ModCRE PWM Open · Scan
a0a8i5kwx0.af3.4 ModCRE AlphaFold3 model ACCTTCTCCCCCACACCATGGAG AlphaFold3 model · ModCRE PWM Open · Scan
a0a8i5kwx0.af3.5 ModCRE AlphaFold3 model GGCGCGCTCCCCAAAACCGGGGGC AlphaFold3 model · ModCRE PWM Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 558 aa
359-558

Region 359-558 6 PWM

Residues
200 aa
Domains
PF13894 · C2H2-type zinc finger PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
12 active PDB models 6 summary rows
Region 359-5586 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_A0A8I5KWX0_A0A8I5KWX0_HUMAN:498:543_1llm_D_1 1llm 498-543 View model · PDB
Predicted = Low TFS_tr_A0A8I5KWX0_A0A8I5KWX0_HUMAN:359:558_5v3j_E_1 5v3j 359-558 View model · PDB
Predicted = Low TFS_tr_A0A8I5KWX0_A0A8I5KWX0_HUMAN:359:558_5v3m_C_1 5v3m 359-558 View model · PDB
Predicted = Low TFS_tr_A0A8I5KWX0_A0A8I5KWX0_HUMAN:361:465_5ei9_E_1 5ei9 361-465 View model · PDB
Predicted = Low TFS_tr_A0A8I5KWX0_A0A8I5KWX0_HUMAN:361:548_5wjq_D_1 5wjq 361-548 View model · PDB
Predicted = Low TFS_tr_A0A8I5KWX0_A0A8I5KWX0_HUMAN:368:519_2i13_A_1 2i13 368-519 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 1llm 355:558 498,498 543,543 P:C,D · DNA:A,B 45.7% / 60.9% 52,54 View · PDB DIMER_tr_A0A8I5KWX0_A0A8I5KWX0_HUMAN:498:543_1llm_D_1
5 5ei9 355:558 361 465 P:E · DNA:A,B 41.0% / 55.2% 94 View · PDB TFS_tr_A0A8I5KWX0_A0A8I5KWX0_HUMAN:361:465_5ei9_E_1
4 2i13 355:558 368 519 P:A · DNA:C,D 37.4% / 51.0% 98 View · PDB TFS_tr_A0A8I5KWX0_A0A8I5KWX0_HUMAN:368:519_2i13_A_1
1 5wjq 355:558 361 548 P:D · DNA:A,B 35.6% / 53.4% 66 View · PDB TFS_tr_A0A8I5KWX0_A0A8I5KWX0_HUMAN:361:548_5wjq_D_1
2 5v3m 355:558 359 558 P:C · DNA:A,B 34.5% / 53.7% 71 View · PDB TFS_tr_A0A8I5KWX0_A0A8I5KWX0_HUMAN:359:558_5v3m_C_1
3 5v3j 355:558 359 558 P:E · DNA:A,B 34.5% / 53.7% 71 View · PDB TFS_tr_A0A8I5KWX0_A0A8I5KWX0_HUMAN:359:558_5v3j_E_1
Full sequence / unlocalized models6 models
SourceModelTemplateResidues modeledActions
Predicted = Lowa0a8i5kwx0.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8i5kwx0.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8i5kwx0.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8i5kwx0.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8i5kwx0.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8i5kwx0.af3.5-Full sequence / not localizedView model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
206-247PF01352KRAB boxNo overlap with loaded model regions
360-381PF13894C2H2-type zinc fingeroverlaps 359-558
498-519PF00096Zinc finger, C2H2 typeoverlaps 359-558
525-547PF00096Zinc finger, C2H2 typeoverlaps 359-558