Transcription factor

A0A8V8TLG8 - STAT2

Signal transducer and activator of transcription

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 807 aa

3 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)2

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
MA0517.1	NN 70+%	JASPAR	TCAGTTTCATTTTCC	94.8% identity		Open · Scan
M08019_2.00	NN 70+%	CisBP	TTCAGTTTCATTTTC	94.3% identity		Open · Scan

Nearest Neighbor (70% - 40%)1

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
MA1623.1	NN 70-40%	JASPAR	AGAAACAGAAACT	61.9% identity		Open · Scan

ModCRE0

No generated PWM in this category.

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 807 aa

406-647

Residues: 242 aa
Domains: PF21354 · Signal transducer and activator of transcription, linker domain PF00017 · SH2 domain
3D models: 1 active PDB
Templates: 4Y5W
Sources: Structure model

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

1 active PDB model

Region 406-6471 model

				Actions
Predicted = Low	DIMER_A0A8V8TLG8:406:647_4y5w_A_1	4y5w	406-647	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
2-122	PF02865	STAT protein, protein interaction domain	No overlap with loaded model regions
146-308	PF01017	STAT transcription factor, coiled-coil domain	No overlap with loaded model regions
321-403	PF02864	STAT protein, DNA binding domain	No overlap with loaded model regions
438-513	PF21354	Signal transducer and activator of transcription, linker domain	overlaps 406-647
534-604	PF00017	SH2 domain	overlaps 406-647
739-794	PF12188	Signal transducer and activator of transcription 2 C terminal	No overlap with loaded model regions