ModCRE DB

Transcription factor

A0A8V8TLS8 - ZBTB24

Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 641 aa

27 Generated PWM 12 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)15
MotifPredictionSourceDNA bindingSupportLogoActions
M00944_2.00 NN 70-40% CisBP TCGCTATAA 55.0% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 53.0% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 53.0% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 53.0% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 51.8% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 51.8% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 50.6% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 50.6% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 50.6% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 50.6% identity Open · Scan
M06072_2.00 NN 70-40% CisBP CCACGCCCACGCAC 50.6% identity Open · Scan
M08371_2.00 NN 70-40% CisBP CCAGACTTGTCCTCT 50.3% identity Open · Scan
M01440_2.00 NN 70-40% CisBP TACGCCAC 50.0% identity Open · Scan
M06068_2.00 NN 70-40% CisBP GGGAATCCCCT 50.0% identity Open · Scan
M08525_2.00 NN 70-40% CisBP CCCCGCA 50.0% identity Open · Scan
ModCRE12
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_A0A8V8TLS8_A0A8V8TLS8_HUMAN:376:424_1llm_D_1 ModCRE Homology model TACGGCCGCAAG Region 376-424 · 1 3D model Open · Scan
TFS_tr_A0A8V8TLS8_A0A8V8TLS8_HUMAN:318:459_6ml5_A_1 ModCRE Homology model CGCCAGTCCTGTGACGGAA Region 318-459 · 1 3D model Open · Scan
TFS_tr_A0A8V8TLS8_A0A8V8TLS8_HUMAN:318:460_6ml4_A_1 ModCRE Homology model CGCAGGTGTTGGCACCCTC Region 318-460 · 1 3D model Open · Scan
TFS_tr_A0A8V8TLS8_A0A8V8TLS8_HUMAN:318:460_6ml6_A_1 ModCRE Homology model CACAAGTCCTGCTCCAAAA Region 318-460 · 1 3D model Open · Scan
TFS_tr_A0A8V8TLS8_A0A8V8TLS8_HUMAN:318:460_6ml7_A_1 ModCRE Homology model CGCAAAGCCTGTTACGGAT Region 318-460 · 1 3D model Open · Scan
TFS_tr_A0A8V8TLS8_A0A8V8TLS8_HUMAN:320:459_6ml2_A_1 ModCRE Homology model CCCCAGTCCTGGTGCAAAT Region 320-459 · 1 3D model Open · Scan
a0a8v8tls8.af3.0 ModCRE AlphaFold3 model GCTACCGGGACCCCCACCCCCCCCCCCA AlphaFold3 model · ModCRE PWM Open · Scan
a0a8v8tls8.af3.1 ModCRE AlphaFold3 model TGGGCCGGGGGTGCCTCACGACGG AlphaFold3 model · ModCRE PWM Open · Scan
a0a8v8tls8.af3.2 ModCRE AlphaFold3 model TGGGGGGGTGGGGGGGGGGCCGGGAGC AlphaFold3 model · ModCRE PWM Open · Scan
a0a8v8tls8.af3.3 ModCRE AlphaFold3 model GGGGGGGGTGGGGGGTCCTTTTCTCGC AlphaFold3 model · ModCRE PWM Open · Scan
a0a8v8tls8.af3.4 ModCRE AlphaFold3 model GCTACCGGGACCCCCACCCCCCCCCCCA AlphaFold3 model · ModCRE PWM Open · Scan
a0a8v8tls8.af3.5 ModCRE AlphaFold3 model CGGGGGGGGGGGGGCGGTCCCAAGTTG AlphaFold3 model · ModCRE PWM Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 641 aa
318-460

Region 318-460 6 PWM

Residues
143 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 6ML2, 6ML4, 6ML5, 6ML6, 6ML7
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
12 active PDB models 6 summary rows
Region 318-4606 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_A0A8V8TLS8_A0A8V8TLS8_HUMAN:376:424_1llm_D_1 1llm 376-424 View model · PDB
Predicted = Low TFS_tr_A0A8V8TLS8_A0A8V8TLS8_HUMAN:318:459_6ml5_A_1 6ml5 318-459 View model · PDB
Predicted = Low TFS_tr_A0A8V8TLS8_A0A8V8TLS8_HUMAN:318:460_6ml4_A_1 6ml4 318-460 View model · PDB
Predicted = Low TFS_tr_A0A8V8TLS8_A0A8V8TLS8_HUMAN:318:460_6ml6_A_1 6ml6 318-460 View model · PDB
Predicted = Low TFS_tr_A0A8V8TLS8_A0A8V8TLS8_HUMAN:318:460_6ml7_A_1 6ml7 318-460 View model · PDB
Predicted = Low TFS_tr_A0A8V8TLS8_A0A8V8TLS8_HUMAN:320:459_6ml2_A_1 6ml2 320-459 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 6ml7 276:460 318 460 P:A · DNA:E,F 95.1% / 95.1% 100 View · PDB TFS_tr_A0A8V8TLS8_A0A8V8TLS8_HUMAN:318:460_6ml7_A_1
2 6ml6 276:460 318 460 P:A · DNA:E,F 95.1% / 95.1% 100 View · PDB TFS_tr_A0A8V8TLS8_A0A8V8TLS8_HUMAN:318:460_6ml6_A_1
3 6ml4 276:460 318 460 P:A · DNA:E,F 95.1% / 95.1% 100 View · PDB TFS_tr_A0A8V8TLS8_A0A8V8TLS8_HUMAN:318:460_6ml4_A_1
4 6ml5 276:460 318 459 P:A · DNA:E,F 95.1% / 95.1% 100 View · PDB TFS_tr_A0A8V8TLS8_A0A8V8TLS8_HUMAN:318:459_6ml5_A_1
5 6ml2 276:460 320 459 P:A · DNA:E,F 94.3% / 94.3% 99 View · PDB TFS_tr_A0A8V8TLS8_A0A8V8TLS8_HUMAN:320:459_6ml2_A_1
1 1llm 276:460 376,376 424,424 P:C,D · DNA:A,B 51.0% / 69.4% 56,57 View · PDB DIMER_tr_A0A8V8TLS8_A0A8V8TLS8_HUMAN:376:424_1llm_D_1
Full sequence / unlocalized models6 models
SourceModelTemplateResidues modeledActions
Predicted = Lowa0a8v8tls8.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tls8.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tls8.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tls8.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tls8.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tls8.af3.5-Full sequence / not localizedView model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
27-132PF00651BTB/POZ domainNo overlap with loaded model regions
295-316PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
322-344PF00096Zinc finger, C2H2 typeoverlaps 318-460
351-372PF00096Zinc finger, C2H2 typeoverlaps 318-460
378-400PF00096Zinc finger, C2H2 typeoverlaps 318-460
434-456PF00096Zinc finger, C2H2 typeoverlaps 318-460