ModCRE DB

Transcription factor

A0A8V8TMC2 - ZBTB24

Zinc finger and BTB domain containing 24

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 457 aa

20 Generated PWM 12 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)8
MotifPredictionSourceDNA bindingSupportLogoActions
M06084_2.00 NN 70-40% CisBP AGACCACCCAC 53.8% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 51.7% identity Open · Scan
M08525_2.00 NN 70-40% CisBP CCCCGCA 50.9% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 50.5% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 50.5% identity Open · Scan
M07601_2.00 NN 70-40% CisBP CAGATGCCGGCACCATGCTTC 50.3% identity Open · Scan
M01883_2.00 NN 70-40% CisBP TGCCCCTGA 50.0% identity Open · Scan
M06179_2.00 NN 70-40% CisBP TAAGCCTATAGA 50.0% identity Open · Scan
ModCRE12
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_A0A8V8TMC2_A0A8V8TMC2_HUMAN:407:452_1llm_D_1 ModCRE Homology model TCGTTTCGCGAA Region 407-452 · 1 3D model Open · Scan
TFS_tr_A0A8V8TMC2_A0A8V8TMC2_HUMAN:374:457_6ml4_A_1 ModCRE Homology model ATGCCCTGCTGCGGAA Region 374-457 · 1 3D model Open · Scan
TFS_tr_A0A8V8TMC2_A0A8V8TMC2_HUMAN:374:457_6ml5_A_1 ModCRE Homology model TTCCACTGTCCCCAAA Region 374-457 · 1 3D model Open · Scan
TFS_tr_A0A8V8TMC2_A0A8V8TMC2_HUMAN:374:457_6ml6_A_1 ModCRE Homology model GTCCTCTGCTCCAGAA Region 374-457 · 1 3D model Open · Scan
TFS_tr_A0A8V8TMC2_A0A8V8TMC2_HUMAN:374:457_6ml7_A_1 ModCRE Homology model ATCCCCTGCCACGGAA Region 374-457 · 1 3D model Open · Scan
TFS_tr_A0A8V8TMC2_A0A8V8TMC2_HUMAN:376:457_6ml2_A_1 ModCRE Homology model ACTCATGCTGCAAAC Region 376-457 · 1 3D model Open · Scan
a0a8v8tmc2.af3.0 ModCRE AlphaFold3 model GGGGGGCGCTGCGGCGGGGGGGAGGGCC AlphaFold3 model · ModCRE PWM Open · Scan
a0a8v8tmc2.af3.1 ModCRE AlphaFold3 model GGGGGGCGCTGCGGCGGGGGGGAGGGCC AlphaFold3 model · ModCRE PWM Open · Scan
a0a8v8tmc2.af3.2 ModCRE AlphaFold3 model GCGCCTCCCCGGCCCCGCGACCGCCCC AlphaFold3 model · ModCRE PWM Open · Scan
a0a8v8tmc2.af3.3 ModCRE AlphaFold3 model GGGCCTCCCCCCCGCCGCGCCCCCCCCC AlphaFold3 model · ModCRE PWM Open · Scan
a0a8v8tmc2.af3.4 ModCRE AlphaFold3 model GGGGGTCCCCACCCCCGCACCCCCCCC AlphaFold3 model · ModCRE PWM Open · Scan
a0a8v8tmc2.af3.5 ModCRE AlphaFold3 model CCCGCTCCCCCCCGCGGCGGCCCCCCCC AlphaFold3 model · ModCRE PWM Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 457 aa
374-457

Region 374-457 6 PWM

Residues
84 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 6ML2, 6ML4, 6ML5, 6ML6, 6ML7
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
12 active PDB models 6 summary rows
Region 374-4576 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_A0A8V8TMC2_A0A8V8TMC2_HUMAN:407:452_1llm_D_1 1llm 407-452 View model · PDB
Predicted = Low TFS_tr_A0A8V8TMC2_A0A8V8TMC2_HUMAN:374:457_6ml4_A_1 6ml4 374-457 View model · PDB
Predicted = Low TFS_tr_A0A8V8TMC2_A0A8V8TMC2_HUMAN:374:457_6ml5_A_1 6ml5 374-457 View model · PDB
Predicted = Low TFS_tr_A0A8V8TMC2_A0A8V8TMC2_HUMAN:374:457_6ml6_A_1 6ml6 374-457 View model · PDB
Predicted = Low TFS_tr_A0A8V8TMC2_A0A8V8TMC2_HUMAN:374:457_6ml7_A_1 6ml7 374-457 View model · PDB
Predicted = Low TFS_tr_A0A8V8TMC2_A0A8V8TMC2_HUMAN:376:457_6ml2_A_1 6ml2 376-457 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 6ml5 276:457 374 457 P:A · DNA:E,F 95.2% / 95.2% 59 View · PDB TFS_tr_A0A8V8TMC2_A0A8V8TMC2_HUMAN:374:457_6ml5_A_1
2 6ml7 276:457 374 457 P:A · DNA:E,F 95.2% / 95.2% 58 View · PDB TFS_tr_A0A8V8TMC2_A0A8V8TMC2_HUMAN:374:457_6ml7_A_1
3 6ml6 276:457 374 457 P:A · DNA:E,F 95.2% / 95.2% 58 View · PDB TFS_tr_A0A8V8TMC2_A0A8V8TMC2_HUMAN:374:457_6ml6_A_1
4 6ml4 276:457 374 457 P:A · DNA:E,F 95.2% / 95.2% 58 View · PDB TFS_tr_A0A8V8TMC2_A0A8V8TMC2_HUMAN:374:457_6ml4_A_1
5 6ml2 276:457 376 457 P:A · DNA:E,F 93.9% / 93.9% 57 View · PDB TFS_tr_A0A8V8TMC2_A0A8V8TMC2_HUMAN:376:457_6ml2_A_1
1 1llm 276:457 407,407 452,452 P:C,D · DNA:A,B 45.7% / 58.7% 52,54 View · PDB DIMER_tr_A0A8V8TMC2_A0A8V8TMC2_HUMAN:407:452_1llm_D_1
Full sequence / unlocalized models6 models
SourceModelTemplateResidues modeledActions
Predicted = Lowa0a8v8tmc2.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmc2.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmc2.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmc2.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmc2.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmc2.af3.5-Full sequence / not localizedView model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
27-132PF00651BTB/POZ domainNo overlap with loaded model regions
295-316PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
322-344PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
350-372PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
378-400PF00096Zinc finger, C2H2 typeoverlaps 374-457
407-428PF00096Zinc finger, C2H2 typeoverlaps 374-457
434-456PF00096Zinc finger, C2H2 typeoverlaps 374-457