ModCRE DB

Transcription factor

A0A8V8TMG8 - ZNF44

Zinc finger protein 44

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 409 aa

35 Generated PWM 24 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)23
MotifPredictionSourceDNA bindingSupportLogoActions
M00939_2.00 NN 70-40% CisBP CCACCTCA 56.4% identity Open · Scan
M07770_2.00 NN 70-40% CisBP CTTGGACTT 56.2% identity Open · Scan
M08366_2.00 NN 70-40% CisBP GTTTGCTGCTTACAA 56.1% identity Open · Scan
M08908_2.00 NN 70-40% CisBP GCTGCTGCTTCTGCTG 55.0% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 54.1% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 53.0% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 53.0% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 53.0% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 53.0% identity Open · Scan
M08367_2.00 NN 70-40% CisBP GGGGTGATGACCACTCTGGCTTCTTAC 52.7% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 51.8% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 51.8% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 51.8% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 51.8% identity Open · Scan
M07731_2.00 NN 70-40% CisBP TTTCCCAGCAGCAACAGCACCGCCCCCCCC 51.3% identity Open · Scan
M06179_2.00 NN 70-40% CisBP TAAGCCTATAGA 51.2% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 50.5% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 50.4% identity Open · Scan
M04463_2.00 NN 70-40% CisBP CACCACGCCCA 50.0% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 50.0% identity Open · Scan
MA0039.1 NN 70-40% JASPAR TAAAGGAAGG 50.0% identity Open · Scan
MA0039.3 NN 70-40% JASPAR CCACACCCTGC 50.0% identity Open · Scan
MA1515.1 NN 70-40% JASPAR CACCACGCCCA 50.0% identity Open · Scan
ModCRE12
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_A0A8V8TMG8_A0A8V8TMG8_HUMAN:251:299_1llm_D_1 ModCRE Homology model TCCCGGCCCCGA Region 251-299 · 1 3D model Open · Scan
TFS_tr_A0A8V8TMG8_A0A8V8TMG8_HUMAN:138:402_5wjq_D_1 ModCRE Homology model CCCCCCGCCGGGGGCCCGGCGGGGCTCT Region 138-402 · 1 3D model Open · Scan
TFS_tr_A0A8V8TMG8_A0A8V8TMG8_HUMAN:140:402_5v3j_E_1 ModCRE Homology model GGGCCCCACCGGGGCCCCCCCGGT Region 140-402 · 1 3D model Open · Scan
TFS_tr_A0A8V8TMG8_A0A8V8TMG8_HUMAN:140:402_5v3m_C_1 ModCRE Homology model CCCCACGGGCGCGGGGGCCCCCCGG Region 140-402 · 1 3D model Open · Scan
TFS_tr_A0A8V8TMG8_A0A8V8TMG8_HUMAN:141:402_7w1m_H_1 ModCRE Homology model AGGGGGGCCCCCCAGAACGACCTTCCCTATCTGCCCCGAGTT Region 141-402 · 1 3D model Open · Scan
TFS_tr_A0A8V8TMG8_A0A8V8TMG8_HUMAN:187:331_2i13_A_1 ModCRE Homology model GGTGCTTAGGAGTTTAAAAAT Region 187-331 · 1 3D model Open · Scan
a0a8v8tmg8.af3.0 ModCRE AlphaFold3 model GCCCCCCCCGGGCACCCCGGGAGACGTGGC AlphaFold3 model · ModCRE PWM Open · Scan
a0a8v8tmg8.af3.1 ModCRE AlphaFold3 model CCCCCGGCCCCGGGGGGCCCAGGGGGGGGC AlphaFold3 model · ModCRE PWM Open · Scan
a0a8v8tmg8.af3.2 ModCRE AlphaFold3 model GGCCCCCCCCCGCCCCCCCCGAGACGCGGG AlphaFold3 model · ModCRE PWM Open · Scan
a0a8v8tmg8.af3.3 ModCRE AlphaFold3 model CCCGCGCCCCCGGGGGGCCCCGGGGGGGCC AlphaFold3 model · ModCRE PWM Open · Scan
a0a8v8tmg8.af3.4 ModCRE AlphaFold3 model GCCCCCCCCGGGCACCCCGGGAGACGTGGC AlphaFold3 model · ModCRE PWM Open · Scan
a0a8v8tmg8.af3.5 ModCRE AlphaFold3 model GCCCCCCCCGGGGCCCCCGGGAGTCGGTCC AlphaFold3 model · ModCRE PWM Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 409 aa
138-402

Region 138-402 6 PWM

Residues
265 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
24 active PDB models 6 summary rows
Region 138-4026 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_A0A8V8TMG8_A0A8V8TMG8_HUMAN:251:299_1llm_D_1 1llm 251-299 View model · PDB
Predicted = Low TFS_tr_A0A8V8TMG8_A0A8V8TMG8_HUMAN:138:402_5wjq_D_1 5wjq 138-402 View model · PDB
Predicted = Low TFS_tr_A0A8V8TMG8_A0A8V8TMG8_HUMAN:140:402_5v3j_E_1 5v3j 140-402 View model · PDB
Predicted = Low TFS_tr_A0A8V8TMG8_A0A8V8TMG8_HUMAN:140:402_5v3m_C_1 5v3m 140-402 View model · PDB
Predicted = Low TFS_tr_A0A8V8TMG8_A0A8V8TMG8_HUMAN:141:402_7w1m_H_1 7w1m 141-402 View model · PDB
Predicted = Low TFS_tr_A0A8V8TMG8_A0A8V8TMG8_HUMAN:187:331_2i13_A_1 2i13 187-331 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 2i13 137:402 187 331 P:A · DNA:C,D 53.1% / 68.3% 94 View · PDB TFS_tr_A0A8V8TMG8_A0A8V8TMG8_HUMAN:187:331_2i13_A_1
1 5v3m 137:402 140 402 P:C · DNA:A,B 47.5% / 61.2% 94 View · PDB TFS_tr_A0A8V8TMG8_A0A8V8TMG8_HUMAN:140:402_5v3m_C_1
2 5v3j 137:402 140 402 P:E · DNA:A,B 47.5% / 61.2% 94 View · PDB TFS_tr_A0A8V8TMG8_A0A8V8TMG8_HUMAN:140:402_5v3j_E_1
3 5wjq 137:402 138 402 P:D · DNA:A,B 45.7% / 62.3% 94 View · PDB TFS_tr_A0A8V8TMG8_A0A8V8TMG8_HUMAN:138:402_5wjq_D_1
1 1llm 137:402 251,251 299,299 P:C,D · DNA:A,B 38.8% / 57.1% 56,57 View · PDB DIMER_tr_A0A8V8TMG8_A0A8V8TMG8_HUMAN:251:299_1llm_D_1
5 7w1m 137:402 141 402 P:H · DNA:F,G 29.6% / 45.7% 81 View · PDB TFS_tr_A0A8V8TMG8_A0A8V8TMG8_HUMAN:141:402_7w1m_H_1
Full sequence / unlocalized models18 models
SourceModelTemplateResidues modeledActions
Predicted = Lowa0a8v8tmg8.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmg8.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmg8.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmg8.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmg8.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmg8.af3.5-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmg8_dimer.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmg8_dimer.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmg8_dimer.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmg8_dimer.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmg8_dimer.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmg8_dimer.af3.5-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmg8_monomer.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmg8_monomer.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmg8_monomer.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmg8_monomer.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmg8_monomer.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a8v8tmg8_monomer.af3.5-Full sequence / not localizedView model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
3-44PF01352KRAB boxNo overlap with loaded model regions
141-163PF00096Zinc finger, C2H2 typeoverlaps 138-402
197-219PF00096Zinc finger, C2H2 typeoverlaps 138-402
225-247PF00096Zinc finger, C2H2 typeoverlaps 138-402
253-275PF00096Zinc finger, C2H2 typeoverlaps 138-402
281-303PF00096Zinc finger, C2H2 typeoverlaps 138-402
365-387PF00096Zinc finger, C2H2 typeoverlaps 138-402