Transcription factor

A0A8V8TPF3 - SATB2

SATB homeobox 2

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 487 aa

8 Generated PWM 24 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE8

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
TFS_tr_A0A8V8TPF3_A0A8V8TPF3_HUMAN:368:444_2o49_A_1	ModCRE	Homology model	GGTATAGCTAC	Region 368-444 · 1 3D model		Open · Scan
TFS_tr_A0A8V8TPF3_A0A8V8TPF3_HUMAN:368:444_2o4a_A_1	ModCRE	Homology model	CGCCTAGCTAA	Region 368-444 · 1 3D model		Open · Scan
a0a8v8tpf3.af3.0	ModCRE	AlphaFold3 model	AAAATATGCCATAGCGCTAGCCAAA	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a8v8tpf3.af3.1	ModCRE	AlphaFold3 model	AAAATAAGCTATAGCGCTAGCCAAA	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a8v8tpf3.af3.2	ModCRE	AlphaFold3 model	ATAAAAATTCATAGAGCTATAGGGGCAA	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a8v8tpf3.af3.3	ModCRE	AlphaFold3 model	ATAATAAGCCATAGAGCTACCCAA	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a8v8tpf3.af3.4	ModCRE	AlphaFold3 model	AAAATATGCCATAGCGCTAGCCAAA	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a8v8tpf3.af3.5	ModCRE	AlphaFold3 model	ATTGCTACGAATAAGCTAT	AlphaFold3 model · ModCRE PWM		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 487 aa

244-326

368-444

Region 244-326 0 PWM

Residues

83 aa

Domains

PF02376 · CUT domain

3D models

4 active PDBs · 4 summary rows

Templates

2D5V, 2O49, 2O4A, 6LFF

Sources

Predicted = Low

Scan this region Show models

Region 368-444 2 PWM

Residues

77 aa

Domains

PF02376 · CUT domain

3D models

2 active PDBs

Templates

2O49, 2O4A

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

24 active PDB models 4 summary rows

Region 244-3264 models · 4 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	TFS_tr_A0A8V8TPF3_A0A8V8TPF3_HUMAN:244:326_2o49_A_1	2o49	244-326	View model · PDB
Predicted = Low	TFS_tr_A0A8V8TPF3_A0A8V8TPF3_HUMAN:244:326_2o4a_A_1	2o4a	244-326	View model · PDB
Predicted = Low	TFS_tr_A0A8V8TPF3_A0A8V8TPF3_HUMAN:245:326_6lff_A_1	6lff	245-326	View model · PDB
Predicted = Low	TFS_tr_A0A8V8TPF3_A0A8V8TPF3_HUMAN:248:314_2d5v_A_1	2d5v	248-314	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
1	2o4a	244:326	244	326	P:A · DNA:B,C	89.2% / 94.0%	98	View · PDB TFS_tr_A0A8V8TPF3_A0A8V8TPF3_HUMAN:244:326_2o4a_A_1
2	2o49	244:326	244	326	P:A · DNA:B,C	89.2% / 94.0%	98	View · PDB TFS_tr_A0A8V8TPF3_A0A8V8TPF3_HUMAN:244:326_2o49_A_1
3	6lff	244:326	245	326	P:A · DNA:C,D	89.0% / 93.9%	100	View · PDB TFS_tr_A0A8V8TPF3_A0A8V8TPF3_HUMAN:245:326_6lff_A_1
4	2d5v	244:326	248	314	P:A · DNA:C,D	37.3% / 59.7%	48	View · PDB TFS_tr_A0A8V8TPF3_A0A8V8TPF3_HUMAN:248:314_2d5v_A_1

Region 368-4442 models

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	TFS_tr_A0A8V8TPF3_A0A8V8TPF3_HUMAN:368:444_2o49_A_1	2o49	368-444	View model · PDB
Predicted = Low	TFS_tr_A0A8V8TPF3_A0A8V8TPF3_HUMAN:368:444_2o4a_A_1	2o4a	368-444	View model · PDB

Full sequence / unlocalized models18 models

Source	Model	Template	Residues modeled	Actions
Predicted = Low	a0a8v8tpf3.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a8v8tpf3.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a8v8tpf3.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a8v8tpf3.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a8v8tpf3.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a8v8tpf3.af3.5	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a8v8tpf3_dimer.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a8v8tpf3_dimer.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a8v8tpf3_dimer.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a8v8tpf3_dimer.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a8v8tpf3_dimer.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a8v8tpf3_dimer.af3.5	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a8v8tpf3_monomer.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a8v8tpf3_monomer.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a8v8tpf3_monomer.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a8v8tpf3_monomer.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a8v8tpf3_monomer.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a8v8tpf3_monomer.af3.5	-	Full sequence / not localized	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
2-41	PF16534	Ubiquitin-like oligomerisation domain of SATB	No overlap with loaded model regions
48-118	PF16557	CUT1-like DNA-binding domain of SATB	No overlap with loaded model regions
245-319	PF02376	CUT domain	overlaps 244-326
366-441	PF02376	CUT domain	overlaps 368-444