ModCRE DB

Transcription factor

A0A994J4F0 - TCF7L2

Transcription factor 7 like 2

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 291 aa

10 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)6
MotifPredictionSourceDNA bindingSupportLogoActions
M08167_2.00 NN 70+% CisBP AAAGATCAAAGGAA 98.2% identity Open · Scan
MA0523.1 NN 70+% JASPAR AAAGATCAAAGGAA 98.2% identity Open · Scan
M00198_2.00 NN 70+% CisBP AGATCAAAGG 98.1% identity Open · Scan
MA1421.1 NN 70+% JASPAR AAAGATCAAAGG 74.7% identity Open · Scan
MA0522.1 NN 70+% JASPAR CACAGCTGCAG 73.4% identity Open · Scan
MA0768.1 NN 70+% JASPAR AAAGATCAAAGGGTT 72.3% identity Open · Scan
Nearest Neighbor (70% - 40%)4
MotifPredictionSourceDNA bindingSupportLogoActions
M09392_2.00 NN 70-40% CisBP TCCTTTGATTTGCT 63.6% identity Open · Scan
MA0769.1 NN 70-40% JASPAR AAAGATCAAAGG 57.5% identity Open · Scan
MA0769.2 NN 70-40% JASPAR TCCTTTGATGT 55.2% identity Open · Scan
M05755_2.00 NN 70-40% CisBP ACATCAAAG 54.1% identity Open · Scan
ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 291 aa
157-226

Region 157-226 0 PWM

Residues
70 aa
Domains
PF00505 · HMG (high mobility group) box
3D models
1 active PDB
Templates
4S2Q
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 157-2261 model
Actions
Predicted = Low TFS_A0A994J4F0:157:226_4s2q_D_1 4s2q 157-226 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
1-63PF08347N-terminal CTNNB1 bindingNo overlap with loaded model regions
159-227PF00505HMG (high mobility group) boxoverlaps 157-226
271-289PF27556Zinc finger protein 704 C-terminal domainNo overlap with loaded model regions