Transcription factor

A0A994J5R8 - ZNF568

Zinc finger protein 568

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 470 aa

88 Generated PWM 24 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)76

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	67.0% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	65.8% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	64.7% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	64.7% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	64.7% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	64.7% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	64.7% identity		Open · Scan
M04653_2.00	NN 70-40%	CisBP	GGTACGGTTGTCCATGTTGCAA	64.5% identity		Open · Scan
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	62.3% identity		Open · Scan
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	62.3% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	61.9% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	60.0% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	60.0% identity		Open · Scan
M08985_2.00	NN 70-40%	CisBP	TGAGGACCTACTGTGTGCC	60.0% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	57.0% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	56.5% identity		Open · Scan
M04465_2.00	NN 70-40%	CisBP	GTGATTCTTATCTTATCCTT	56.4% identity		Open · Scan
M08366_2.00	NN 70-40%	CisBP	GTTTGCTGCTTACAA	56.3% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	56.0% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	56.0% identity		Open · Scan
M08935_2.00	NN 70-40%	CisBP	CCTCCTCCCTCAGACC	55.6% identity		Open · Scan
M07648_2.00	NN 70-40%	CisBP	GCTTGCAAAAAAAATTTAACTCCCAGCTC	55.2% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	55.0% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	54.8% identity		Open · Scan
M07649_2.00	NN 70-40%	CisBP	CCCCCCCCCCCCTCAGGAATGCC	54.7% identity		Open · Scan
M07598_2.00	NN 70-40%	CisBP	CTGACAATACCAAGTGTTGAC	54.5% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	54.3% identity		Open · Scan
M07762_2.00	NN 70-40%	CisBP	GCCGCGCACAGGCTTCTAGCC	54.2% identity		Open · Scan
M08901_2.00	NN 70-40%	CisBP	CCAGTTCACACC	54.2% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	54.0% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	53.9% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	53.8% identity		Open · Scan
M07699_2.00	NN 70-40%	CisBP	GGTTTAT	53.6% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	53.6% identity		Open · Scan
M08279_2.00	NN 70-40%	CisBP	CCTCCCTCC	53.5% identity		Open · Scan
M07565_2.00	NN 70-40%	CisBP	CCTCTGGGGGCTCGTCCA	53.4% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	53.3% identity		Open · Scan
M07620_2.00	NN 70-40%	CisBP	TTGGATCTGTGGATTCATGTCTTTCAT	53.2% identity		Open · Scan
M08347_2.00	NN 70-40%	CisBP	GCCCTGGGCAGC	53.2% identity		Open · Scan
MA0130.1	NN 70-40%	JASPAR	ATCCAC	53.1% identity		Open · Scan
MA1587.1	NN 70-40%	JASPAR	CCTCGACCTCCTGA	53.0% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	52.9% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	52.7% identity		Open · Scan
M07753_2.00	NN 70-40%	CisBP	TGCATTCCTTGGCTTGTG	52.4% identity		Open · Scan
M04590_2.00	NN 70-40%	CisBP	TGCGCTAACCATTGC	52.2% identity		Open · Scan
M08252_2.00	NN 70-40%	CisBP	CCGGCTCCAGCACCC	52.2% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	52.0% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	51.9% identity		Open · Scan
M08263_2.00	NN 70-40%	CisBP	ATCTCGGCACTTTGGGAGGCCA	51.9% identity		Open · Scan
M07566_2.00	NN 70-40%	CisBP	TCAAACCATCCTTGC	51.8% identity		Open · Scan
M07707_2.00	NN 70-40%	CisBP	TCCCGC	51.8% identity		Open · Scan
M07689_2.00	NN 70-40%	CisBP	ACCCAGGCTCCTTCCATCTTGTGGCTC	51.2% identity		Open · Scan
M07764_2.00	NN 70-40%	CisBP	CTGCACTCTCCCCTTCCCCCCCTCCCC	51.2% identity		Open · Scan
M08860_2.00	NN 70-40%	CisBP	TCTTATAAGGGCACTAATCCCATT	51.2% identity		Open · Scan
MA1600.1	NN 70-40%	JASPAR	ATACAGTCCACCCCTTTA	51.0% identity		Open · Scan
M07590_2.00	NN 70-40%	CisBP	TTTTTTTCTTTTATTTTTTTTTTTTTTTTTTTT	50.9% identity		Open · Scan
M08392_2.00	NN 70-40%	CisBP	CTTCACCTGCTGAGG	50.7% identity		Open · Scan
M08395_2.00	NN 70-40%	CisBP	GCTGCCTACTCTTCC	50.7% identity		Open · Scan
MA1656.1	NN 70-40%	JASPAR	CCAAGCCCAACCAG	50.7% identity		Open · Scan
M05853_2.00	NN 70-40%	CisBP	CCACCTTTAGCCATATCT	50.6% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	50.6% identity		Open · Scan
M07646_2.00	NN 70-40%	CisBP	CTTTTTTTT	50.6% identity		Open · Scan
M07667_2.00	NN 70-40%	CisBP	CCGCACAGGCCCCCGGGCCCC	50.6% identity		Open · Scan
M08255_2.00	NN 70-40%	CisBP	CTCTTCCGGT	50.6% identity		Open · Scan
M08247_2.00	NN 70-40%	CisBP	AAAAATAACAAACGG	50.5% identity		Open · Scan
MA1594.1	NN 70-40%	JASPAR	AGGGGACATCACTACAGATCCCAC	50.5% identity		Open · Scan
M07601_2.00	NN 70-40%	CisBP	CAGATGCCGGCACCATGCTTC	50.3% identity		Open · Scan
M08311_2.00	NN 70-40%	CisBP	CTGGAACAGAAGGGGCGA	50.2% identity		Open · Scan
M07658_2.00	NN 70-40%	CisBP	CCGCCGCAGCCGCCG	50.1% identity		Open · Scan
M01456_2.00	NN 70-40%	CisBP	GTGATCGGCG	50.0% identity		Open · Scan
M04611_2.00	NN 70-40%	CisBP	CTTTCGGACAC	50.0% identity		Open · Scan
M07678_2.00	NN 70-40%	CisBP	CCCGCCCCCTCCTCCCCCTTCCCACCC	50.0% identity		Open · Scan
M07683_2.00	NN 70-40%	CisBP	GTGGGAAAGCCT	50.0% identity		Open · Scan
M07712_2.00	NN 70-40%	CisBP	ACATTTTTTTAATCTAAAAAAACATTTACA	50.0% identity		Open · Scan
MA1597.1	NN 70-40%	JASPAR	CCCAGGGAAGCCATTTC	50.0% identity		Open · Scan
MA1601.1	NN 70-40%	JASPAR	ATGTGGGAAA	50.0% identity		Open · Scan

ModCRE12

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
DIMER_tr_A0A994J5R8_A0A994J5R8_HUMAN:368:419_1llm_D_1	ModCRE	Homology model	CCCGCCGGCGGG	Region 368-419 · 1 3D model		Open · Scan
TFS_tr_A0A994J5R8_A0A994J5R8_HUMAN:201:470_5v3j_E_1	ModCRE	Homology model	ACGCCGGGGGCCCCGAGGGGGGGGG	Region 201-470 · 1 3D model		Open · Scan
TFS_tr_A0A994J5R8_A0A994J5R8_HUMAN:201:470_5v3m_C_1	ModCRE	Homology model	ATTTCCGGGGGGGGGCGCCGGGGCCC	Region 201-470 · 1 3D model		Open · Scan
TFS_tr_A0A994J5R8_A0A994J5R8_HUMAN:227:470_5wjq_D_1	ModCRE	Homology model	ACTGGCGTGGGGGGGCGGCGGGGCCT	Region 227-470 · 1 3D model		Open · Scan
TFS_tr_A0A994J5R8_A0A994J5R8_HUMAN:267:420_2i13_A_1	ModCRE	Homology model	GTAACGAACTTCTCTGCGGGC	Region 267-420 · 1 3D model		Open · Scan
TFS_tr_A0A994J5R8_A0A994J5R8_HUMAN:339:449_5ei9_E_1	ModCRE	Homology model	CCCCCGGGGCGGCCCCG	Region 339-449 · 1 3D model		Open · Scan
a0a994j5r8.af3.0	ModCRE	AlphaFold3 model	AGGGATCCCCCGGCCCCCCCCCCCCG	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a994j5r8.af3.1	ModCRE	AlphaFold3 model	GGGGGGGGGGGCGGCGGGCGATCCC	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a994j5r8.af3.2	ModCRE	AlphaFold3 model	GGGGGGGGGGGGGGCCGGGGCTCCC	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a994j5r8.af3.3	ModCRE	AlphaFold3 model	GGGATCCCGGGGCCCCCCCCCCCCG	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a994j5r8.af3.4	ModCRE	AlphaFold3 model	GGGAGGCAGGGGCCCCCCCCCGCCG	AlphaFold3 model · ModCRE PWM		Open · Scan
a0a994j5r8.af3.5	ModCRE	AlphaFold3 model	AGGGTTCCCCCGGCCCCCCCCCCCCG	AlphaFold3 model · ModCRE PWM		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 470 aa

201-470

Region 201-470 6 PWM

Residues

270 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

6 active PDBs · 6 summary rows

Templates

1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

24 active PDB models 6 summary rows

Region 201-4706 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_tr_A0A994J5R8_A0A994J5R8_HUMAN:368:419_1llm_D_1	1llm	368-419	View model · PDB
Predicted = Low	TFS_tr_A0A994J5R8_A0A994J5R8_HUMAN:201:470_5v3j_E_1	5v3j	201-470	View model · PDB
Predicted = Low	TFS_tr_A0A994J5R8_A0A994J5R8_HUMAN:201:470_5v3m_C_1	5v3m	201-470	View model · PDB
Predicted = Low	TFS_tr_A0A994J5R8_A0A994J5R8_HUMAN:227:470_5wjq_D_1	5wjq	227-470	View model · PDB
Predicted = Low	TFS_tr_A0A994J5R8_A0A994J5R8_HUMAN:267:420_2i13_A_1	2i13	267-420	View model · PDB
Predicted = Low	TFS_tr_A0A994J5R8_A0A994J5R8_HUMAN:339:449_5ei9_E_1	5ei9	339-449	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
3	5wjq	185:470	227	470	P:D · DNA:A,B	82.8% / 90.2%	86	View · PDB TFS_tr_A0A994J5R8_A0A994J5R8_HUMAN:227:470_5wjq_D_1
1	5v3m	185:470	201	470	P:C · DNA:A,B	81.9% / 90.4%	97	View · PDB TFS_tr_A0A994J5R8_A0A994J5R8_HUMAN:201:470_5v3m_C_1
2	5v3j	185:470	201	470	P:E · DNA:A,B	81.9% / 90.4%	97	View · PDB TFS_tr_A0A994J5R8_A0A994J5R8_HUMAN:201:470_5v3j_E_1
5	5ei9	185:470	339	449	P:E · DNA:A,B	55.9% / 73.0%	100	View · PDB TFS_tr_A0A994J5R8_A0A994J5R8_HUMAN:339:449_5ei9_E_1
4	2i13	185:470	267	420	P:A · DNA:C,D	55.8% / 65.6%	100	View · PDB TFS_tr_A0A994J5R8_A0A994J5R8_HUMAN:267:420_2i13_A_1
1	1llm	185:470	368,368	419,419	P:C,D · DNA:A,B	44.2% / 59.6%	59,61	View · PDB DIMER_tr_A0A994J5R8_A0A994J5R8_HUMAN:368:419_1llm_D_1

Full sequence / unlocalized models18 models

Source	Model	Template	Residues modeled	Actions
Predicted = Low	a0a994j5r8.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a994j5r8.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a994j5r8.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a994j5r8.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a994j5r8.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a994j5r8.af3.5	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a994j5r8_dimer.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a994j5r8_dimer.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a994j5r8_dimer.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a994j5r8_dimer.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a994j5r8_dimer.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a994j5r8_dimer.af3.5	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a994j5r8_monomer.af3.0	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a994j5r8_monomer.af3.1	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a994j5r8_monomer.af3.2	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a994j5r8_monomer.af3.3	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a994j5r8_monomer.af3.4	-	Full sequence / not localized	View model · PDB
Predicted = Low	a0a994j5r8_monomer.af3.5	-	Full sequence / not localized	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
202-224	PF00096	Zinc finger, C2H2 type	overlaps 201-470
230-252	PF00096	Zinc finger, C2H2 type	overlaps 201-470
263-280	PF00096	Zinc finger, C2H2 type	overlaps 201-470
286-308	PF00096	Zinc finger, C2H2 type	overlaps 201-470
314-336	PF00096	Zinc finger, C2H2 type	overlaps 201-470
342-364	PF00096	Zinc finger, C2H2 type	overlaps 201-470
370-392	PF00096	Zinc finger, C2H2 type	overlaps 201-470
398-420	PF00096	Zinc finger, C2H2 type	overlaps 201-470
426-448	PF00096	Zinc finger, C2H2 type	overlaps 201-470