ModCRE DB

Transcription factor

A0A994J7H0 - MBD1

Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 680 aa

14 Generated PWM 12 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)3
MotifPredictionSourceDNA bindingSupportLogoActions
M01907_2.00 NN 70-40% CisBP TTCGCGTAAACG 52.0% identity Open · Scan
M01910_2.00 NN 70-40% CisBP GCGGAAATT 51.0% identity Open · Scan
M01921_2.00 NN 70-40% CisBP AAATTACGGA 50.0% identity Open · Scan
ModCRE11
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_tr_A0A994J7H0_A0A994J7H0_HUMAN:358:402_3qmb_A_1 ModCRE Homology model GACCCCGCGGGG Region 358-402 · 1 3D model Open · Scan
TFS_tr_A0A994J7H0_A0A994J7H0_HUMAN:361:402_3qmc_A_1 ModCRE Homology model GCCCCCGCGGGG Region 361-402 · 1 3D model Open · Scan
TFS_tr_A0A994J7H0_A0A994J7H0_HUMAN:361:402_3qmd_A_1 ModCRE Homology model CCCCCCGCGGGG Region 361-402 · 1 3D model Open · Scan
TFS_tr_A0A994J7H0_A0A994J7H0_HUMAN:361:402_3qmh_A_1 ModCRE Homology model CCCCGCCGCGGG Region 361-402 · 1 3D model Open · Scan
TFS_tr_A0A994J7H0_A0A994J7H0_HUMAN:361:402_3qmi_A_1 ModCRE Homology model CCCCCCCGGGGC Region 361-402 · 1 3D model Open · Scan
a0a994j7h0.af3.0 ModCRE AlphaFold3 model ACGGCGCGCCCGGGGACCACCCGGCGCCGC AlphaFold3 model · ModCRE PWM Open · Scan
a0a994j7h0.af3.1 ModCRE AlphaFold3 model CCCCCCCGGGGCCCAAGGCGCCCCCGG AlphaFold3 model · ModCRE PWM Open · Scan
a0a994j7h0.af3.2 ModCRE AlphaFold3 model AGGTTCCCCCCGGCGCAACGCGGCGGCCG AlphaFold3 model · ModCRE PWM Open · Scan
a0a994j7h0.af3.3 ModCRE AlphaFold3 model CCGTGGGGAACCCTGGTGGGGCGCGCCGGG AlphaFold3 model · ModCRE PWM Open · Scan
a0a994j7h0.af3.4 ModCRE AlphaFold3 model ACGGCGCGCCCGGGGACCACCCGGCGCCGC AlphaFold3 model · ModCRE PWM Open · Scan
a0a994j7h0.af3.5 ModCRE AlphaFold3 model GGCCGGGGCCGCGGGGCGGGGCGCGGCCCT AlphaFold3 model · ModCRE PWM Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 680 aa
358-407

Region 358-407 5 PWM

Residues
50 aa
Domains
PF02008 · CXXC zinc finger domain
3D models
6 active PDBs · 6 summary rows
Templates
3QMB, 3QMC, 3QMD, 3QMH, 3QMI, 4HN6
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
12 active PDB models 6 summary rows
Region 358-4076 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_A0A994J7H0_A0A994J7H0_HUMAN:363:407_4hn6_B_1 4hn6 363-407 View model · PDB
Predicted = Low TFS_tr_A0A994J7H0_A0A994J7H0_HUMAN:358:402_3qmb_A_1 3qmb 358-402 View model · PDB
Predicted = Low TFS_tr_A0A994J7H0_A0A994J7H0_HUMAN:361:402_3qmc_A_1 3qmc 361-402 View model · PDB
Predicted = Low TFS_tr_A0A994J7H0_A0A994J7H0_HUMAN:361:402_3qmd_A_1 3qmd 361-402 View model · PDB
Predicted = Low TFS_tr_A0A994J7H0_A0A994J7H0_HUMAN:361:402_3qmh_A_1 3qmh 361-402 View model · PDB
Predicted = Low TFS_tr_A0A994J7H0_A0A994J7H0_HUMAN:361:402_3qmi_A_1 3qmi 361-402 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
2 3qmd 358:408 361 402 P:A · DNA:B,C 66.7% / 69.0% 79 View · PDB TFS_tr_A0A994J7H0_A0A994J7H0_HUMAN:361:402_3qmd_A_1
3 3qmc 358:408 361 402 P:A · DNA:B,C 66.7% / 69.0% 79 View · PDB TFS_tr_A0A994J7H0_A0A994J7H0_HUMAN:361:402_3qmc_A_1
4 3qmh 358:408 361 402 P:A · DNA:B,C 66.7% / 69.0% 79 View · PDB TFS_tr_A0A994J7H0_A0A994J7H0_HUMAN:361:402_3qmh_A_1
5 3qmi 358:408 361 402 P:A · DNA:B,C 66.7% / 69.0% 80 View · PDB TFS_tr_A0A994J7H0_A0A994J7H0_HUMAN:361:402_3qmi_A_1
1 3qmb 358:408 358 402 P:A · DNA:B,C 64.4% / 66.7% 83 View · PDB TFS_tr_A0A994J7H0_A0A994J7H0_HUMAN:358:402_3qmb_A_1
1 4hn6 358:408 363,363 407,407 P:A,B · DNA:C,D 30.6% / 51.0% 62,62 View · PDB DIMER_tr_A0A994J7H0_A0A994J7H0_HUMAN:363:407_4hn6_B_1
Full sequence / unlocalized models6 models
SourceModelTemplateResidues modeledActions
Predicted = Lowa0a994j7h0.af3.0-Full sequence / not localizedView model · PDB
Predicted = Lowa0a994j7h0.af3.1-Full sequence / not localizedView model · PDB
Predicted = Lowa0a994j7h0.af3.2-Full sequence / not localizedView model · PDB
Predicted = Lowa0a994j7h0.af3.3-Full sequence / not localizedView model · PDB
Predicted = Lowa0a994j7h0.af3.4-Full sequence / not localizedView model · PDB
Predicted = Lowa0a994j7h0.af3.5-Full sequence / not localizedView model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
2-70PF01429Methyl-CpG binding domainNo overlap with loaded model regions
169-215PF02008CXXC zinc finger domainNo overlap with loaded model regions
219-262PF02008CXXC zinc finger domainNo overlap with loaded model regions
356-402PF02008CXXC zinc finger domainoverlaps 358-407