ModCRE DB

Transcription factor

A0JP08 - ZEB2

Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (Zinc finger homeobox protein 1b)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 1213 aa

39 Generated PWM 11 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)29
MotifPredictionSourceDNA bindingSupportLogoActions
M07842_2.00 NN 70-40% CisBP CTCACCTG 60.8% identity Open · Scan
M06179_2.00 NN 70-40% CisBP TAAGCCTATAGA 56.8% identity Open · Scan
M08860_2.00 NN 70-40% CisBP TCTTATAAGGGCACTAATCCCATT 55.8% identity Open · Scan
M08335_2.00 NN 70-40% CisBP AGTCGTTGTCTG 53.6% identity Open · Scan
MA1587.1 NN 70-40% JASPAR CCTCGACCTCCTGA 53.3% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 53.0% identity Open · Scan
M07753_2.00 NN 70-40% CisBP TGCATTCCTTGGCTTGTG 52.7% identity Open · Scan
M08311_2.00 NN 70-40% CisBP CTGGAACAGAAGGGGCGA 52.2% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 52.1% identity Open · Scan
M07684_2.00 NN 70-40% CisBP CCTGTTCTTGACTTT 52.1% identity Open · Scan
M08390_2.00 NN 70-40% CisBP GCTTTGTTGACTCAC 51.5% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 51.4% identity Open · Scan
M07601_2.00 NN 70-40% CisBP CAGATGCCGGCACCATGCTTC 51.4% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 51.3% identity Open · Scan
M08347_2.00 NN 70-40% CisBP GCCCTGGGCAGC 51.3% identity Open · Scan
M08300_2.00 NN 70-40% CisBP CTGCCCAATTCAT 51.2% identity Open · Scan
M07667_2.00 NN 70-40% CisBP CCGCACAGGCCCCCGGGCCCC 50.7% identity Open · Scan
M08252_2.00 NN 70-40% CisBP CCGGCTCCAGCACCC 50.7% identity Open · Scan
M04475_2.00 NN 70-40% CisBP GATGCACGTACCGTGCCTCA 50.6% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 50.6% identity Open · Scan
M07590_2.00 NN 70-40% CisBP TTTTTTTCTTTTATTTTTTTTTTTTTTTTTTTT 50.6% identity Open · Scan
M01468_2.00 NN 70-40% CisBP TTACCCCTGA 50.0% identity Open · Scan
M01883_2.00 NN 70-40% CisBP TGCCCCTGA 50.0% identity Open · Scan
M07567_2.00 NN 70-40% CisBP CCACTCCACTCA 50.0% identity Open · Scan
M07600_2.00 NN 70-40% CisBP GCATTAGC 50.0% identity Open · Scan
M08373_2.00 NN 70-40% CisBP CCCCCTGGCTCTTCCTCT 50.0% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 50.0% identity Open · Scan
MA0038.1 NN 70-40% JASPAR CAAATCACTG 50.0% identity Open · Scan
MA0038.2 NN 70-40% JASPAR CAAATCACTGCA 50.0% identity Open · Scan
ModCRE10
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_A0JP08_A0JP08_HUMAN:658:695_1au7_B_1 ModCRE Homology model TTTTTAACTTCATCGCTTTCAAGA Region 658-695 · 1 3D model Open · Scan
DIMER_tr_A0JP08_A0JP08_HUMAN:658:695_1hf0_B_1 ModCRE Homology model CTTAAAAGGAAATCTAATTAAG Region 658-695 · 1 3D model Open · Scan
TFS_tr_A0JP08_A0JP08_HUMAN:212:263_5k5l_F_1 ModCRE Homology model GTAACACACTTGTA Region 212-263 · 1 3D model Open · Scan
TFS_tr_A0JP08_A0JP08_HUMAN:279:328_4gzn_C_1 ModCRE Homology model GGCCCCCCCC Region 279-328 · 1 3D model Open · Scan
TFS_tr_A0JP08_A0JP08_HUMAN:279:328_4m9v_C_1 ModCRE Homology model GACCCCCCCC Region 279-328 · 1 3D model Open · Scan
TFS_tr_A0JP08_A0JP08_HUMAN:998:1072_1a1g_A_1 ModCRE Homology model GCGCCCCCCC Region 998-1072 · 1 3D model Open · Scan
TFS_tr_A0JP08_A0JP08_HUMAN:998:1072_1a1h_A_1 ModCRE Homology model GCCGGCGACG Region 998-1072 · 1 3D model Open · Scan
TFS_tr_A0JP08_A0JP08_HUMAN:998:1072_1a1i_A_1 ModCRE Homology model CCGGCCCCCC Region 998-1072 · 1 3D model Open · Scan
TFS_tr_A0JP08_A0JP08_HUMAN:998:1072_1a1j_A_1 ModCRE Homology model GCGCCCCCCC Region 998-1072 · 1 3D model Open · Scan
TFS_tr_A0JP08_A0JP08_HUMAN:998:1072_1a1k_A_1 ModCRE Homology model CCGGCCCGCG Region 998-1072 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 1213 aa
212-263
279-328
658-695
998-1072

Region 212-263 1 PWM

Residues
52 aa
Domains
PF05605 · Drought induced 19 protein (Di19), zinc-binding
3D models
1 active PDB
Templates
5K5L
Sources
Predicted = Low
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Region 279-328 2 PWM

Residues
50 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
2 active PDBs
Templates
4GZN, 4M9V
Sources
Predicted = Low
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Region 658-695 2 PWM

Residues
38 aa
Domains
No overlapping PFAM annotation recorded
3D models
2 active PDBs
Templates
1AU7, 1HF0
Sources
Predicted = Low
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Region 998-1072 5 PWM

Residues
75 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1A1G, 1A1H, 1A1I, 1A1J, 1A1K, 1LLM
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
11 active PDB models 6 summary rows
Region 212-2631 model
Actions
Predicted = Low TFS_tr_A0JP08_A0JP08_HUMAN:212:263_5k5l_F_1 5k5l 212-263 View model · PDB
Region 279-3282 models
Actions
Predicted = Low TFS_tr_A0JP08_A0JP08_HUMAN:279:328_4gzn_C_1 4gzn 279-328 View model · PDB
Predicted = Low TFS_tr_A0JP08_A0JP08_HUMAN:279:328_4m9v_C_1 4m9v 279-328 View model · PDB
Region 658-6952 models
Actions
Predicted = Low DIMER_tr_A0JP08_A0JP08_HUMAN:658:695_1au7_B_1 1au7 658-695 View model · PDB
Predicted = Low DIMER_tr_A0JP08_A0JP08_HUMAN:658:695_1hf0_B_1 1hf0 658-695 View model · PDB
Region 998-10726 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_A0JP08_A0JP08_HUMAN:1024:1072_1llm_D_1 1llm 1024-1072 View model · PDB
Predicted = Low TFS_tr_A0JP08_A0JP08_HUMAN:998:1072_1a1g_A_1 1a1g 998-1072 View model · PDB
Predicted = Low TFS_tr_A0JP08_A0JP08_HUMAN:998:1072_1a1h_A_1 1a1h 998-1072 View model · PDB
Predicted = Low TFS_tr_A0JP08_A0JP08_HUMAN:998:1072_1a1i_A_1 1a1i 998-1072 View model · PDB
Predicted = Low TFS_tr_A0JP08_A0JP08_HUMAN:998:1072_1a1j_A_1 1a1j 998-1072 View model · PDB
Predicted = Low TFS_tr_A0JP08_A0JP08_HUMAN:998:1072_1a1k_A_1 1a1k 998-1072 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 1a1h 981:1078 998 1072 P:A · DNA:B,C 46.8% / 63.6% 88 View · PDB TFS_tr_A0JP08_A0JP08_HUMAN:998:1072_1a1h_A_1
5 1a1g 981:1078 998 1072 P:A · DNA:B,C 46.8% / 63.6% 89 View · PDB TFS_tr_A0JP08_A0JP08_HUMAN:998:1072_1a1g_A_1
1 1a1j 981:1078 998 1072 P:A · DNA:B,C 45.5% / 63.6% 89 View · PDB TFS_tr_A0JP08_A0JP08_HUMAN:998:1072_1a1j_A_1
2 1a1k 981:1078 998 1072 P:A · DNA:B,C 45.5% / 63.6% 88 View · PDB TFS_tr_A0JP08_A0JP08_HUMAN:998:1072_1a1k_A_1
3 1a1i 981:1078 998 1072 P:A · DNA:B,C 45.5% / 63.6% 88 View · PDB TFS_tr_A0JP08_A0JP08_HUMAN:998:1072_1a1i_A_1
1 1llm 981:1078 1024,1024 1072,1072 P:C,D · DNA:A,B 44.9% / 63.3% 56,57 View · PDB DIMER_tr_A0JP08_A0JP08_HUMAN:1024:1072_1llm_D_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
210-261PF05605Drought induced 19 protein (Di19), zinc-bindingoverlaps 212-263
281-303PF00096Zinc finger, C2H2 typeoverlaps 279-328
309-329PF00096Zinc finger, C2H2 typeoverlaps 279-328
998-1020PF00096Zinc finger, C2H2 typeoverlaps 998-1072
1054-1074PF00096Zinc finger, C2H2 typeoverlaps 998-1072