ModCRE DB

Transcription factor

A6NCS4 - NKX2-6

Homeobox protein Nkx-2.6 (Homeobox protein NK-2 homolog F)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 301 aa

85 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)3
MotifPredictionSourceDNA bindingSupportLogoActions
MA1645.1 NN 70+% JASPAR TAACCACTCAAGAA 73.0% identity Open · Scan
M03854_2.00 NN 70+% CisBP GTGAAGTGG 72.9% identity Open · Scan
M02181_2.00 NN 70+% CisBP TTAAGTGGT 70.4% identity Open · Scan
Nearest Neighbor (70% - 40%)82
MotifPredictionSourceDNA bindingSupportLogoActions
MA0124.1 NN 70-40% JASPAR ATACTTA 66.6% identity Open · Scan
MA0673.1 NN 70-40% JASPAR CCACTTGAA 63.8% identity Open · Scan
M06232_2.00 NN 70-40% CisBP TTAATGA 62.7% identity Open · Scan
MA0876.1 NN 70-40% JASPAR CCAATTAA 62.7% identity Open · Scan
M00520_2.00 NN 70-40% CisBP CTTAAGTGCT 61.8% identity Open · Scan
M06378_2.00 NN 70-40% CisBP GCTCAAGTGC 61.6% identity Open · Scan
MA0122.2 NN 70-40% JASPAR ACCACTTAA 61.1% identity Open · Scan
M00526_2.00 NN 70-40% CisBP ATTAATTA 61.0% identity Open · Scan
M05392_2.00 NN 70-40% CisBP GTTAAGTGC 61.0% identity Open · Scan
MA1577.1 NN 70-40% JASPAR CTAATTAG 61.0% identity Open · Scan
MA0124.2 NN 70-40% JASPAR ACCACTTAA 60.9% identity Open · Scan
M09146_2.00 NN 70-40% CisBP CTTGAGTGGC 60.5% identity Open · Scan
M02106_2.00 NN 70-40% CisBP ATATTAATTGGTT 60.3% identity Open · Scan
MA0063.1 NN 70-40% JASPAR TTAATTG 59.7% identity Open · Scan
M01503_2.00 NN 70-40% CisBP TTAATTAC 59.6% identity Open · Scan
M05179_2.00 NN 70-40% CisBP ATAATTGC 59.6% identity Open · Scan
M06544_2.00 NN 70-40% CisBP GTAATTA 59.6% identity Open · Scan
MA0879.1 NN 70-40% JASPAR CCTAATTATC 59.6% identity Open · Scan
MA0880.1 NN 70-40% JASPAR CCAATTAC 59.6% identity Open · Scan
M00385_2.00 NN 70-40% CisBP TTAAGTGG 59.2% identity Open · Scan
MA0063.2 NN 70-40% JASPAR ACCACTCAAAA 59.0% identity Open · Scan
M00496_2.00 NN 70-40% CisBP TTAAGTGGTT 58.2% identity Open · Scan
M06504_2.00 NN 70-40% CisBP TTAAGTG 58.1% identity Open · Scan
M04906_2.00 NN 70-40% CisBP ATAACGAC 57.8% identity Open · Scan
M09195_2.00 NN 70-40% CisBP TAATTATAGGT 57.8% identity Open · Scan
MA0882.1 NN 70-40% JASPAR CCAATTAC 57.8% identity Open · Scan
MA1476.1 NN 70-40% JASPAR GCAATTAC 57.8% identity Open · Scan
M00451_2.00 NN 70-40% CisBP ATTAATTA 56.8% identity Open · Scan
M02128_2.00 NN 70-40% CisBP ATTAATTA 56.8% identity Open · Scan
M03798_2.00 NN 70-40% CisBP GGTAATTAGC 56.8% identity Open · Scan
M00465_2.00 NN 70-40% CisBP TTAATTAG 56.6% identity Open · Scan
M06286_2.00 NN 70-40% CisBP CTTAAGTG 56.3% identity Open · Scan
MA0635.1 NN 70-40% JASPAR GCTAAACGGT 55.5% identity Open · Scan
MA0709.1 NN 70-40% JASPAR CCAATTAA 55.5% identity Open · Scan
MA0877.1 NN 70-40% JASPAR GCTAATTGCT 55.1% identity Open · Scan
MA0877.2 NN 70-40% JASPAR CTAAACGG 55.1% identity Open · Scan
M06361_2.00 NN 70-40% CisBP TTTAATTA 54.9% identity Open · Scan
MA0675.1 NN 70-40% JASPAR CTAATTAA 54.9% identity Open · Scan
M00388_2.00 NN 70-40% CisBP CTAATTGCTT 54.8% identity Open · Scan
M03777_2.00 NN 70-40% CisBP GTAATTGC 54.8% identity Open · Scan
MA0707.1 NN 70-40% JASPAR GGTAATTAAA 54.8% identity Open · Scan
MA0666.1 NN 70-40% JASPAR CCAATTAG 54.6% identity Open · Scan
M05027_2.00 NN 70-40% CisBP ATAATTAC 54.5% identity Open · Scan
M06290_2.00 NN 70-40% CisBP TTTAATTA 54.2% identity Open · Scan
M02164_2.00 NN 70-40% CisBP GTAATGGGCT 53.5% identity Open · Scan
M00438_2.00 NN 70-40% CisBP TTTAAGTGC 53.4% identity Open · Scan
M09565_2.00 NN 70-40% CisBP GTTAATGGCC 53.4% identity Open · Scan
MA1530.1 NN 70-40% JASPAR CTCATTAAA 52.9% identity Open · Scan
M06359_2.00 NN 70-40% CisBP TTTAATTA 52.8% identity Open · Scan
M09573_2.00 NN 70-40% CisBP GTTAATGA 52.7% identity Open · Scan
MA0674.1 NN 70-40% JASPAR GTAATTAA 52.7% identity Open · Scan
M03832_2.00 NN 70-40% CisBP GGTAATTACC 52.6% identity Open · Scan
MA0119.1 NN 70-40% JASPAR TGGCACCATGCCAA 52.5% identity Open · Scan
M02170_2.00 NN 70-40% CisBP TTAATTAG 52.4% identity Open · Scan
M02148_2.00 NN 70-40% CisBP CTAATTAG 51.6% identity Open · Scan
M02210_2.00 NN 70-40% CisBP AAGTACTTAA 51.6% identity Open · Scan
M03775_2.00 NN 70-40% CisBP GTTTTATGTGTTTT 51.6% identity Open · Scan
M06323_2.00 NN 70-40% CisBP ATTAATTG 51.6% identity Open · Scan
M03814_2.00 NN 70-40% CisBP GTAATGGC 51.5% identity Open · Scan
MA0885.1 NN 70-40% JASPAR GCAATTAA 51.4% identity Open · Scan
M00461_2.00 NN 70-40% CisBP ATGATACCC 51.2% identity Open · Scan
M04940_2.00 NN 70-40% CisBP CCGTATCATT 51.2% identity Open · Scan
M02153_2.00 NN 70-40% CisBP GCCCAATAAA 50.9% identity Open · Scan
M02165_2.00 NN 70-40% CisBP CTTAATTGG 50.9% identity Open · Scan
M06539_2.00 NN 70-40% CisBP CTAATTA 50.9% identity Open · Scan
M03152_2.00 NN 70-40% CisBP TAATTAGCTAATTA 50.7% identity Open · Scan
M05003_2.00 NN 70-40% CisBP ATAACGAC 50.7% identity Open · Scan
M06264_2.00 NN 70-40% CisBP GCTAATTA 50.7% identity Open · Scan
M06339_2.00 NN 70-40% CisBP TTTAATTGG 50.7% identity Open · Scan
MA0612.1 NN 70-40% JASPAR CCTAATTACC 50.7% identity Open · Scan
MA0886.1 NN 70-40% JASPAR GCTAATTAGC 50.7% identity Open · Scan
M10805_2.00 NN 70-40% CisBP GGACAAATAGCCC 50.6% identity Open · Scan
MA0708.1 NN 70-40% JASPAR CCAATTAA 50.6% identity Open · Scan
M05042_2.00 NN 70-40% CisBP GTCAAGTGGT 50.5% identity Open · Scan
M06554_2.00 NN 70-40% CisBP TTAATTG 50.5% identity Open · Scan
MA0672.1 NN 70-40% JASPAR ACCACTTGAA 50.5% identity Open · Scan
MA0122.1 NN 70-40% JASPAR TTAAGTGGA 50.3% identity Open · Scan
M00492_2.00 NN 70-40% CisBP TAATTAGC 50.0% identity Open · Scan
M06261_2.00 NN 70-40% CisBP TTAATTA 50.0% identity Open · Scan
M06329_2.00 NN 70-40% CisBP CACTAATTA 50.0% identity Open · Scan
M06548_2.00 NN 70-40% CisBP TTAATTG 50.0% identity Open · Scan
MA0618.1 NN 70-40% JASPAR TTAATTAG 50.0% identity Open · Scan
ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 301 aa
132-188

Region 132-188 0 PWM

Residues
57 aa
Domains
PF00046 · Homeodomain
3D models
1 active PDB
Templates
3RKQ
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 132-1881 model
Actions
Predicted = Low DIMER_A6NCS4:132:188_3rkq_A_1 3rkq 132-188 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
133-189PF00046Homeodomainoverlaps 132-188