Transcription factor

A6NP11 - ZNF716

Zinc finger protein 716

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 495 aa

82 Generated PWM 9 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M07664_2.00	Known	CisBP	AATTTTCCTATTTCC	Direct PWM		Open · Scan

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)77

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	69.4% identity		Open · Scan
M07715_2.00	NN 70-40%	CisBP	CCGCCGCCGCCGTGG	69.1% identity		Open · Scan
M08921_2.00	NN 70-40%	CisBP	CCTCATTCTTCTTGGACATG	68.9% identity		Open · Scan
M07687_2.00	NN 70-40%	CisBP	ACAAATAAGGTTCTTGTGCCCCCTGCT	67.5% identity		Open · Scan
M08934_2.00	NN 70-40%	CisBP	GCTGTACCTGCTTATTAGGC	66.6% identity		Open · Scan
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	65.8% identity		Open · Scan
M07775_2.00	NN 70-40%	CisBP	GCCGAAACCCGGG	65.6% identity		Open · Scan
M04653_2.00	NN 70-40%	CisBP	GGTACGGTTGTCCATGTTGCAA	65.0% identity		Open · Scan
M08295_2.00	NN 70-40%	CisBP	CTGCTGGAATCTCCA	65.0% identity		Open · Scan
M07586_2.00	NN 70-40%	CisBP	GGGACCCGGGTGGGGGCGTCCCCC	64.3% identity		Open · Scan
M08985_2.00	NN 70-40%	CisBP	TGAGGACCTACTGTGTGCC	63.9% identity		Open · Scan
M07565_2.00	NN 70-40%	CisBP	CCTCTGGGGGCTCGTCCA	63.7% identity		Open · Scan
MA1599.1	NN 70-40%	JASPAR	CGGGCCAAGCCCCTAT	63.7% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	63.5% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	62.3% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	62.3% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	62.3% identity		Open · Scan
M07761_2.00	NN 70-40%	CisBP	CTGATTATTCACCCA	62.3% identity		Open · Scan
M08381_2.00	NN 70-40%	CisBP	ACATTTTGTCCTCCTAGTCCT	62.2% identity		Open · Scan
M07714_2.00	NN 70-40%	CisBP	AGCCCATTGGGGCCTATGCCC	61.6% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	61.1% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	61.1% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	61.1% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	60.6% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	60.0% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	60.0% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	60.0% identity		Open · Scan
M07767_2.00	NN 70-40%	CisBP	AAAAACCCCAGA	59.1% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	57.7% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	57.6% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	57.5% identity		Open · Scan
M07638_2.00	NN 70-40%	CisBP	TGCAGCTCCCTGCCC	57.1% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	56.7% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	56.5% identity		Open · Scan
M07678_2.00	NN 70-40%	CisBP	CCCGCCCCCTCCTCCCCCTTCCCACCC	56.4% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	55.7% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	55.5% identity		Open · Scan
M08314_2.00	NN 70-40%	CisBP	ATTCATCAAGGTCCTCAACAATGG	55.5% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	55.4% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	55.4% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	55.3% identity		Open · Scan
M08335_2.00	NN 70-40%	CisBP	AGTCGTTGTCTG	55.3% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	55.1% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	55.0% identity		Open · Scan
M08245_2.00	NN 70-40%	CisBP	TGGTGCCTTATTCCC	54.9% identity		Open · Scan
M08263_2.00	NN 70-40%	CisBP	ATCTCGGCACTTTGGGAGGCCA	54.9% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	54.5% identity		Open · Scan
M00645_2.00	NN 70-40%	CisBP	CGCCCACGCA	54.2% identity		Open · Scan
M07587_2.00	NN 70-40%	CisBP	CCCCCTCCCCAGTCGAGCCCCCGC	54.2% identity		Open · Scan
M04465_2.00	NN 70-40%	CisBP	GTGATTCTTATCTTATCCTT	54.1% identity		Open · Scan
M08901_2.00	NN 70-40%	CisBP	CCAGTTCACACC	54.1% identity		Open · Scan
M01474_2.00	NN 70-40%	CisBP	CGCCGATCAC	54.0% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	54.0% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	54.0% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	53.7% identity		Open · Scan
M07753_2.00	NN 70-40%	CisBP	TGCATTCCTTGGCTTGTG	53.5% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	53.3% identity		Open · Scan
M01456_2.00	NN 70-40%	CisBP	GTGATCGGCG	52.8% identity		Open · Scan
M08292_2.00	NN 70-40%	CisBP	TGTATTCCTTGTCATGTGTGG	52.7% identity		Open · Scan
M01442_2.00	NN 70-40%	CisBP	ACCCCACATT	52.5% identity		Open · Scan
M07660_2.00	NN 70-40%	CisBP	CCGCGCCTACCTGAGGGCGCGGGCCTGGGG	52.3% identity		Open · Scan
M00609_2.00	NN 70-40%	CisBP	GGAAGCCCTA	52.2% identity		Open · Scan
M01044_2.00	NN 70-40%	CisBP	TCTCTCTTTC	52.1% identity		Open · Scan
M04611_2.00	NN 70-40%	CisBP	CTTTCGGACAC	52.1% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	52.1% identity		Open · Scan
M08283_2.00	NN 70-40%	CisBP	GACTTTTATTTT	52.0% identity		Open · Scan
M07562_2.00	NN 70-40%	CisBP	GAAAAAAAC	51.7% identity		Open · Scan
M08247_2.00	NN 70-40%	CisBP	AAAAATAACAAACGG	51.7% identity		Open · Scan
M06466_2.00	NN 70-40%	CisBP	TCCGCCCCCT	51.4% identity		Open · Scan
M08395_2.00	NN 70-40%	CisBP	GCTGCCTACTCTTCC	51.4% identity		Open · Scan
M08392_2.00	NN 70-40%	CisBP	CTTCACCTGCTGAGG	51.3% identity		Open · Scan
M08908_2.00	NN 70-40%	CisBP	GCTGCTGCTTCTGCTG	51.2% identity		Open · Scan
M07777_2.00	NN 70-40%	CisBP	GCCAATTTCCGTGGTGTAAAT	50.7% identity		Open · Scan
M00764_2.00	NN 70-40%	CisBP	GTCTACAC	50.6% identity		Open · Scan
M03671_2.00	NN 70-40%	CisBP	ATTACCATACAAGTGCAC	50.0% identity		Open · Scan
M04590_2.00	NN 70-40%	CisBP	TGCGCTAACCATTGC	50.0% identity		Open · Scan
M06179_2.00	NN 70-40%	CisBP	TAAGCCTATAGA	50.0% identity		Open · Scan

ModCRE4

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
DIMER_sp_A6NP11_ZN716_HUMAN:294:343_1llm_D_1	ModCRE	Homology model	TTTGGGGCGAGG	Region 294-343 · 1 3D model		Open · Scan
TFS_sp_A6NP11_ZN716_HUMAN:293:403_5egb_A_1	ModCRE	Homology model	AGGGGGGGGGGGGGGCGG	Region 293-403 · 1 3D model		Open · Scan
TFS_sp_A6NP11_ZN716_HUMAN:293:403_5ei9_E_1	ModCRE	Homology model	TCGCGGGGGACCCCCCC	Region 293-403 · 1 3D model		Open · Scan
TFS_sp_A6NP11_ZN716_HUMAN:295:403_5eh2_F_1	ModCRE	Homology model	TCGCGGGGCGGGGGGCCGA	Region 295-403 · 1 3D model		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 495 aa

182-487

Region 182-487 4 PWM

Residues

306 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

9 active PDBs · 6 summary rows

Templates

1LLM, 2I13, 5EGB, 5EH2, 5EI9, 5V3J, 5V3M, 5WJQ, ...

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

9 active PDB models 6 summary rows

Region 182-4879 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_sp_A6NP11_ZN716_HUMAN:294:343_1llm_D_1	1llm	294-343	View model · PDB
Predicted = Low	TFS_sp_A6NP11_ZN716_HUMAN:182:459_5wjq_D_1	5wjq	182-459	View model · PDB
Predicted = Low	TFS_sp_A6NP11_ZN716_HUMAN:212:482_7w1m_H_1	7w1m	212-482	View model · PDB
Predicted = Low	TFS_sp_A6NP11_ZN716_HUMAN:213:487_5v3j_E_1	5v3j	213-487	View model · PDB
Predicted = Low	TFS_sp_A6NP11_ZN716_HUMAN:213:487_5v3m_C_1	5v3m	213-487	View model · PDB
Predicted = Low	TFS_sp_A6NP11_ZN716_HUMAN:293:403_5egb_A_1	5egb	293-403	View model · PDB
Predicted = Low	TFS_sp_A6NP11_ZN716_HUMAN:293:403_5ei9_E_1	5ei9	293-403	View model · PDB
Predicted = Low	TFS_sp_A6NP11_ZN716_HUMAN:295:403_5eh2_F_1	5eh2	295-403	View model · PDB
Predicted = Low	TFS_sp_A6NP11_ZN716_HUMAN:305:458_2i13_A_1	2i13	305-458	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
4	2i13	182:489	305	458	P:A · DNA:C,D	55.8% / 67.5%	100	View · PDB TFS_sp_A6NP11_ZN716_HUMAN:305:458_2i13_A_1
1	5v3m	182:489	213	487	P:C · DNA:A,B	51.4% / 71.4%	99	View · PDB TFS_sp_A6NP11_ZN716_HUMAN:213:487_5v3m_C_1
2	5v3j	182:489	213	487	P:E · DNA:A,B	51.4% / 71.4%	99	View · PDB TFS_sp_A6NP11_ZN716_HUMAN:213:487_5v3j_E_1
3	5wjq	182:489	182	459	P:D · DNA:A,B	50.5% / 70.6%	98	View · PDB TFS_sp_A6NP11_ZN716_HUMAN:182:459_5wjq_D_1
1	1llm	182:489	294,294	343,343	P:C,D · DNA:A,B	48.0% / 66.0%	57,58	View · PDB DIMER_sp_A6NP11_ZN716_HUMAN:294:343_1llm_D_1
5	7w1m	182:489	212	482	P:H · DNA:F,G	36.5% / 48.4%	84	View · PDB TFS_sp_A6NP11_ZN716_HUMAN:212:482_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
16-56	PF01352	KRAB box	No overlap with loaded model regions
213-235	PF00096	Zinc finger, C2H2 type	overlaps 182-487
241-263	PF00096	Zinc finger, C2H2 type	overlaps 182-487
296-318	PF00096	Zinc finger, C2H2 type	overlaps 182-487
324-346	PF00096	Zinc finger, C2H2 type	overlaps 182-487
352-374	PF00096	Zinc finger, C2H2 type	overlaps 182-487
380-402	PF00096	Zinc finger, C2H2 type	overlaps 182-487
408-430	PF00096	Zinc finger, C2H2 type	overlaps 182-487
436-458	PF00096	Zinc finger, C2H2 type	overlaps 182-487
464-486	PF00096	Zinc finger, C2H2 type	overlaps 182-487