ModCRE DB

Transcription factor

A8K124

cDNA FLJ76213, highly similar to Homo sapiens suppressor of hairy wing homolog 4 (Drosophila) (SUHW4), transcript variant 2, mRNA

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 966 aa

11 Generated PWM 11 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)1
MotifPredictionSourceDNA bindingSupportLogoActions
M08332_2.00 NN 70-40% CisBP TCTCTCCAGTGTGAATTCTCTGAT 52.1% identity Open · Scan
ModCRE10
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_tr_A8K124_A8K124_HUMAN:342:456_5ei9_E_1 ModCRE Homology model GCGGCTTTTGGCAGGCC Region 342-456 · 1 3D model Open · Scan
TFS_tr_A8K124_A8K124_HUMAN:346:486_6ml2_A_1 ModCRE Homology model CAGGGCACTTTTGCCGCCC Region 346-486 · 1 3D model Open · Scan
TFS_tr_A8K124_A8K124_HUMAN:346:486_6ml4_A_1 ModCRE Homology model GGGGGCCCTTTTTCCCCCC Region 346-486 · 1 3D model Open · Scan
TFS_tr_A8K124_A8K124_HUMAN:346:486_6ml5_A_1 ModCRE Homology model GGGGAGTTTTTTTCCCCCC Region 346-486 · 1 3D model Open · Scan
TFS_tr_A8K124_A8K124_HUMAN:346:486_6ml6_A_1 ModCRE Homology model GGGGAGTTTCGAGCCCCCC Region 346-486 · 1 3D model Open · Scan
TFS_tr_A8K124_A8K124_HUMAN:346:486_6ml7_A_1 ModCRE Homology model GGAGGGCTTTTGACCCCCC Region 346-486 · 1 3D model Open · Scan
TFS_tr_A8K124_A8K124_HUMAN:347:484_5v3j_E_1 ModCRE Homology model TTCCAGTCGATCTGTC Region 347-484 · 1 3D model Open · Scan
TFS_tr_A8K124_A8K124_HUMAN:347:484_5v3m_C_1 ModCRE Homology model TTCCTTTCTCTCGAAGA Region 347-484 · 1 3D model Open · Scan
TFS_tr_A8K124_A8K124_HUMAN:347:484_5wjq_D_1 ModCRE Homology model TCCCCTTGTATCGATCA Region 347-484 · 1 3D model Open · Scan
TFS_tr_A8K124_A8K124_HUMAN:347:485_5t0u_A_1 ModCRE Homology model CGCTAGCTGGAAAGTATATTTAC Region 347-485 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 966 aa
342-486

Region 342-486 10 PWM

Residues
145 aa
Domains
No overlapping PFAM annotation recorded
3D models
11 active PDBs · 6 summary rows
Templates
1LLM, 5EI9, 5T0U, 5V3J, 5V3M, 5WJQ, 6ML2, 6ML4, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
11 active PDB models 6 summary rows
Region 342-48611 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_A8K124_A8K124_HUMAN:377:428_1llm_C_1 1llm 377-428 View model · PDB
Predicted = Low TFS_tr_A8K124_A8K124_HUMAN:342:456_5ei9_E_1 5ei9 342-456 View model · PDB
Predicted = Low TFS_tr_A8K124_A8K124_HUMAN:346:486_6ml2_A_1 6ml2 346-486 View model · PDB
Predicted = Low TFS_tr_A8K124_A8K124_HUMAN:346:486_6ml4_A_1 6ml4 346-486 View model · PDB
Predicted = Low TFS_tr_A8K124_A8K124_HUMAN:346:486_6ml5_A_1 6ml5 346-486 View model · PDB
Predicted = Low TFS_tr_A8K124_A8K124_HUMAN:346:486_6ml6_A_1 6ml6 346-486 View model · PDB
Predicted = Low TFS_tr_A8K124_A8K124_HUMAN:346:486_6ml7_A_1 6ml7 346-486 View model · PDB
Predicted = Low TFS_tr_A8K124_A8K124_HUMAN:347:484_5v3j_E_1 5v3j 347-484 View model · PDB
Predicted = Low TFS_tr_A8K124_A8K124_HUMAN:347:484_5v3m_C_1 5v3m 347-484 View model · PDB
Predicted = Low TFS_tr_A8K124_A8K124_HUMAN:347:484_5wjq_D_1 5wjq 347-484 View model · PDB
Predicted = Low TFS_tr_A8K124_A8K124_HUMAN:347:485_5t0u_A_1 5t0u 347-485 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 6ml7 334:506 346 486 P:A · DNA:E,F 27.7% / 40.4% 95 View · PDB TFS_tr_A8K124_A8K124_HUMAN:346:486_6ml7_A_1
2 6ml6 334:506 346 486 P:A · DNA:E,F 27.7% / 40.4% 95 View · PDB TFS_tr_A8K124_A8K124_HUMAN:346:486_6ml6_A_1
3 6ml4 334:506 346 486 P:A · DNA:E,F 27.7% / 40.4% 95 View · PDB TFS_tr_A8K124_A8K124_HUMAN:346:486_6ml4_A_1
4 6ml5 334:506 346 486 P:A · DNA:E,F 27.7% / 40.4% 95 View · PDB TFS_tr_A8K124_A8K124_HUMAN:346:486_6ml5_A_1
5 6ml2 334:506 346 486 P:A · DNA:E,F 27.0% / 39.7% 96 View · PDB TFS_tr_A8K124_A8K124_HUMAN:346:486_6ml2_A_1
1 1llm 334:506 377,377 428,428 P:C,D · DNA:A,B 25.0% / 46.2% 57,58 View · PDB DIMER_tr_A8K124_A8K124_HUMAN:377:428_1llm_C_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
32-216PF13836Domain of unknown function (DUF4195)No overlap with loaded model regions
610-651PF25429POGZ-like double zinc fingerNo overlap with loaded model regions
673-711PF25414Z280C/D-like C2H2 zinc fingerNo overlap with loaded model regions