ModCRE DB

Transcription factor

A8K4L4 - ZNF77

Zinc finger protein 77 (PT1)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 545 aa

51 Generated PWM 6 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)47
MotifPredictionSourceDNA bindingSupportLogoActions
M00939_2.00 NN 70-40% CisBP CCACCTCA 63.5% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 62.3% identity Open · Scan
M07733_2.00 NN 70-40% CisBP TCTTTCTCTCTCTCC 61.7% identity Open · Scan
M07689_2.00 NN 70-40% CisBP ACCCAGGCTCCTTCCATCTTGTGGCTC 60.1% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 58.8% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 58.8% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 58.8% identity Open · Scan
M01474_2.00 NN 70-40% CisBP CGCCGATCAC 58.8% identity Open · Scan
M07635_2.00 NN 70-40% CisBP AAGTTTTCTTGTATTATATCT 58.0% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 57.6% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 57.6% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 57.6% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 56.4% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 56.4% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 56.4% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 55.1% identity Open · Scan
M07678_2.00 NN 70-40% CisBP CCCGCCCCCTCCTCCCCCTTCCCACCC 54.8% identity Open · Scan
M07700_2.00 NN 70-40% CisBP ATGTTGTGAGGAAGCCCA 54.8% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 54.7% identity Open · Scan
MA1589.1 NN 70-40% JASPAR TAGGAGTGGAATTGCTGGGTC 53.9% identity Open · Scan
M08274_2.00 NN 70-40% CisBP TTACTTGCAGCCCAACGCATTCCTAAC 53.3% identity Open · Scan
M08254_2.00 NN 70-40% CisBP CTGCCCTGGGACTTT 53.2% identity Open · Scan
M07613_2.00 NN 70-40% CisBP TCACTCAGTCATTCA 52.9% identity Open · Scan
M01456_2.00 NN 70-40% CisBP GTGATCGGCG 52.8% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 52.8% identity Open · Scan
M07686_2.00 NN 70-40% CisBP TAGCTTGTTTCCAGCCAC 52.6% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 52.2% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 52.0% identity Open · Scan
M08901_2.00 NN 70-40% CisBP CCAGTTCACACC 52.0% identity Open · Scan
M07775_2.00 NN 70-40% CisBP GCCGAAACCCGGG 51.6% identity Open · Scan
M08887_2.00 NN 70-40% CisBP CCTCCTCCAGGAAGCCTTCCCTGA 51.3% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 50.8% identity Open · Scan
M07587_2.00 NN 70-40% CisBP CCCCCTCCCCAGTCGAGCCCCCGC 50.8% identity Open · Scan
M04505_2.00 NN 70-40% CisBP AGCTTTTCCCACAC 50.7% identity Open · Scan
M08283_2.00 NN 70-40% CisBP GACTTTTATTTT 50.7% identity Open · Scan
M07566_2.00 NN 70-40% CisBP TCAAACCATCCTTGC 50.5% identity Open · Scan
M00786_2.00 NN 70-40% CisBP TATATATAT 50.2% identity Open · Scan
M04536_2.00 NN 70-40% CisBP ACGTAACCCGATACC 50.2% identity Open · Scan
M07715_2.00 NN 70-40% CisBP CCGCCGCCGCCGTGG 50.1% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 50.0% identity Open · Scan
M02913_2.00 NN 70-40% CisBP TTCGTGGCATTTTTCTA 50.0% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 50.0% identity Open · Scan
M07687_2.00 NN 70-40% CisBP ACAAATAAGGTTCTTGTGCCCCCTGCT 50.0% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 50.0% identity Open · Scan
M08390_2.00 NN 70-40% CisBP GCTTTGTTGACTCAC 50.0% identity Open · Scan
M08908_2.00 NN 70-40% CisBP GCTGCTGCTTCTGCTG 50.0% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 50.0% identity Open · Scan
ModCRE4
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_tr_A8K4L4_A8K4L4_HUMAN:208:487_5wjq_D_1 ModCRE Homology model CTAACCACCCCCCCGGCGGGCCCGAACC Region 208-487 · 1 3D model Open · Scan
TFS_tr_A8K4L4_A8K4L4_HUMAN:267:542_5v3j_E_1 ModCRE Homology model TCCGGAGACTGGGGGCCGGGGGGCCC Region 267-542 · 1 3D model Open · Scan
TFS_tr_A8K4L4_A8K4L4_HUMAN:267:542_5v3m_C_1 ModCRE Homology model CCCCCCCCCCCCCCCCCACCCCACAA Region 267-542 · 1 3D model Open · Scan
TFS_tr_A8K4L4_A8K4L4_HUMAN:277:430_2i13_A_1 ModCRE Homology model AAAAAGCCTCTACTACTTCAA Region 277-430 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 545 aa
208-542

Region 208-542 4 PWM

Residues
335 aa
Domains
PF13465 · Zinc-finger double domain PF13894 · C2H2-type zinc finger PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
6 active PDB models 6 summary rows
Region 208-5426 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_A8K4L4_A8K4L4_HUMAN:405:454_1llm_D_1 1llm 405-454 View model · PDB
Predicted = Low TFS_tr_A8K4L4_A8K4L4_HUMAN:208:487_5wjq_D_1 5wjq 208-487 View model · PDB
Predicted = Low TFS_tr_A8K4L4_A8K4L4_HUMAN:239:538_7w1m_H_1 7w1m 239-538 View model · PDB
Predicted = Low TFS_tr_A8K4L4_A8K4L4_HUMAN:267:542_5v3j_E_1 5v3j 267-542 View model · PDB
Predicted = Low TFS_tr_A8K4L4_A8K4L4_HUMAN:267:542_5v3m_C_1 5v3m 267-542 View model · PDB
Predicted = Low TFS_tr_A8K4L4_A8K4L4_HUMAN:277:430_2i13_A_1 2i13 277-430 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 2i13 208:543 277 430 P:A · DNA:C,D 53.9% / 66.2% 100 View · PDB TFS_tr_A8K4L4_A8K4L4_HUMAN:277:430_2i13_A_1
1 5wjq 208:543 208 487 P:D · DNA:A,B 51.4% / 63.9% 99 View · PDB TFS_tr_A8K4L4_A8K4L4_HUMAN:208:487_5wjq_D_1
2 5v3m 208:543 267 542 P:C · DNA:A,B 48.6% / 63.8% 99 View · PDB TFS_tr_A8K4L4_A8K4L4_HUMAN:267:542_5v3m_C_1
3 5v3j 208:543 267 542 P:E · DNA:A,B 48.6% / 63.8% 99 View · PDB TFS_tr_A8K4L4_A8K4L4_HUMAN:267:542_5v3j_E_1
1 1llm 208:543 405,405 454,454 P:C,D · DNA:A,B 46.0% / 64.0% 57,58 View · PDB DIMER_tr_A8K4L4_A8K4L4_HUMAN:405:454_1llm_D_1
5 7w1m 208:543 239 538 P:H · DNA:F,G 33.3% / 50.8% 93 View · PDB TFS_tr_A8K4L4_A8K4L4_HUMAN:239:538_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
3-44PF01352KRAB boxNo overlap with loaded model regions
254-279PF13465Zinc-finger double domainoverlaps 208-542
296-318PF13894C2H2-type zinc fingeroverlaps 208-542
352-374PF00096Zinc finger, C2H2 typeoverlaps 208-542
408-430PF00096Zinc finger, C2H2 typeoverlaps 208-542
436-458PF00096Zinc finger, C2H2 typeoverlaps 208-542
464-486PF00096Zinc finger, C2H2 typeoverlaps 208-542
492-514PF00096Zinc finger, C2H2 typeoverlaps 208-542
520-542PF00096Zinc finger, C2H2 typeoverlaps 208-542