Transcription factor

A8K4S9

Signal transducer and activator of transcription

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 847 aa

2 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)2

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M11365_2.00	NN 70+%	CisBP	GACTTCCT	99.8% identity		Open · Scan
MA0520.1	NN 70+%	JASPAR	CATTTCCTGAGAAAT	85.4% identity		Open · Scan

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 847 aa

125-651

Residues: 527 aa
Domains: PF01017 · STAT transcription factor, coiled-coil domain PF02864 · STAT protein, DNA binding domain PF21354 · Signal transducer and activator of transcription, linker domain PF00017 · SH2 domain
3D models: 1 active PDB
Templates: 5D39
Sources: Structure model

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

1 active PDB model

Region 125-6511 model

				Actions
Predicted = Low	DIMER_A8K4S9:125:651_5d39_D_1	5d39	125-651	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
2-113	PF02865	STAT protein, protein interaction domain	No overlap with loaded model regions
182-242	PF01017	STAT transcription factor, coiled-coil domain	overlaps 125-651
277-413	PF02864	STAT protein, DNA binding domain	overlaps 125-651
436-518	PF21354	Signal transducer and activator of transcription, linker domain	overlaps 125-651
538-616	PF00017	SH2 domain	overlaps 125-651
655-847	PF14596	STAT6 C-terminal	No overlap with loaded model regions