ModCRE DB

Transcription factor

A8K654

Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 605 aa

9 Generated PWM 6 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)3
MotifPredictionSourceDNA bindingSupportLogoActions
M01907_2.00 NN 70-40% CisBP TTCGCGTAAACG 52.0% identity Open · Scan
M01910_2.00 NN 70-40% CisBP GCGGAAATT 51.0% identity Open · Scan
M01921_2.00 NN 70-40% CisBP AAATTACGGA 50.0% identity Open · Scan
ModCRE6
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_A8K654_A8K654_HUMAN:338:382_4hn6_B_1 ModCRE Homology model TTGTGTCACACACTGA Region 338-382 · 1 3D model Open · Scan
TFS_tr_A8K654_A8K654_HUMAN:333:377_3qmb_A_1 ModCRE Homology model CCCCGCGGGGCC Region 333-377 · 1 3D model Open · Scan
TFS_tr_A8K654_A8K654_HUMAN:336:377_3qmc_A_1 ModCRE Homology model CCCCCCGGGGGC Region 336-377 · 1 3D model Open · Scan
TFS_tr_A8K654_A8K654_HUMAN:336:377_3qmd_A_1 ModCRE Homology model CCCCGCGGGGGG Region 336-377 · 1 3D model Open · Scan
TFS_tr_A8K654_A8K654_HUMAN:336:377_3qmh_A_1 ModCRE Homology model ACCCCGGCGGGG Region 336-377 · 1 3D model Open · Scan
TFS_tr_A8K654_A8K654_HUMAN:336:377_3qmi_A_1 ModCRE Homology model CCCCCGGCGGGG Region 336-377 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 605 aa
333-382

Region 333-382 6 PWM

Residues
50 aa
Domains
PF02008 · CXXC zinc finger domain
3D models
6 active PDBs · 6 summary rows
Templates
3QMB, 3QMC, 3QMD, 3QMH, 3QMI, 4HN6
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
6 active PDB models 6 summary rows
Region 333-3826 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_A8K654_A8K654_HUMAN:338:382_4hn6_B_1 4hn6 338-382 View model · PDB
Predicted = Low TFS_tr_A8K654_A8K654_HUMAN:333:377_3qmb_A_1 3qmb 333-377 View model · PDB
Predicted = Low TFS_tr_A8K654_A8K654_HUMAN:336:377_3qmc_A_1 3qmc 336-377 View model · PDB
Predicted = Low TFS_tr_A8K654_A8K654_HUMAN:336:377_3qmd_A_1 3qmd 336-377 View model · PDB
Predicted = Low TFS_tr_A8K654_A8K654_HUMAN:336:377_3qmh_A_1 3qmh 336-377 View model · PDB
Predicted = Low TFS_tr_A8K654_A8K654_HUMAN:336:377_3qmi_A_1 3qmi 336-377 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
2 3qmd 333:383 336 377 P:A · DNA:B,C 66.7% / 69.0% 79 View · PDB TFS_tr_A8K654_A8K654_HUMAN:336:377_3qmd_A_1
3 3qmc 333:383 336 377 P:A · DNA:B,C 66.7% / 69.0% 79 View · PDB TFS_tr_A8K654_A8K654_HUMAN:336:377_3qmc_A_1
4 3qmh 333:383 336 377 P:A · DNA:B,C 66.7% / 69.0% 79 View · PDB TFS_tr_A8K654_A8K654_HUMAN:336:377_3qmh_A_1
5 3qmi 333:383 336 377 P:A · DNA:B,C 66.7% / 69.0% 80 View · PDB TFS_tr_A8K654_A8K654_HUMAN:336:377_3qmi_A_1
1 3qmb 333:383 333 377 P:A · DNA:B,C 64.4% / 66.7% 83 View · PDB TFS_tr_A8K654_A8K654_HUMAN:333:377_3qmb_A_1
1 4hn6 333:383 338,338 382,382 P:A,B · DNA:C,D 30.6% / 51.0% 62,62 View · PDB DIMER_tr_A8K654_A8K654_HUMAN:338:382_4hn6_B_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
2-70PF01429Methyl-CpG binding domainNo overlap with loaded model regions
169-215PF02008CXXC zinc finger domainNo overlap with loaded model regions
219-262PF02008CXXC zinc finger domainNo overlap with loaded model regions
331-377PF02008CXXC zinc finger domainoverlaps 333-382