ModCRE DB

Transcription factor

A8K8U0

cDNA FLJ77606, highly similar to Homo sapiens zinc finger protein 625 (ZNF625), mRNA

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 306 aa

62 Generated PWM 6 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)57
MotifPredictionSourceDNA bindingSupportLogoActions
M00939_2.00 NN 70-40% CisBP CCACCTCA 68.2% identity Open · Scan
M07628_2.00 NN 70-40% CisBP AGTGGTTCTGCTTCT 63.8% identity Open · Scan
M07733_2.00 NN 70-40% CisBP TCTTTCTCTCTCTCC 61.7% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 61.1% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 61.1% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 61.1% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 61.1% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 61.1% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 60.0% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 60.0% identity Open · Scan
M01474_2.00 NN 70-40% CisBP CGCCGATCAC 60.0% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 58.8% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 58.8% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 58.8% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 58.6% identity Open · Scan
MA1588.1 NN 70-40% JASPAR GAATTCTTGGTTGAC 58.2% identity Open · Scan
M04653_2.00 NN 70-40% CisBP GGTACGGTTGTCCATGTTGCAA 58.0% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 56.6% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 56.3% identity Open · Scan
M08908_2.00 NN 70-40% CisBP GCTGCTGCTTCTGCTG 56.0% identity Open · Scan
M07762_2.00 NN 70-40% CisBP GCCGCGCACAGGCTTCTAGCC 55.9% identity Open · Scan
M08309_2.00 NN 70-40% CisBP AAAAACCCCCCTGCAGAGCCCAGCCCT 54.8% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 54.7% identity Open · Scan
M08917_2.00 NN 70-40% CisBP GCTGAGCCATGTGGGGTGCT 54.5% identity Open · Scan
M07700_2.00 NN 70-40% CisBP ATGTTGTGAGGAAGCCCA 54.3% identity Open · Scan
M07731_2.00 NN 70-40% CisBP TTTCCCAGCAGCAACAGCACCGCCCCCCCC 54.3% identity Open · Scan
M08934_2.00 NN 70-40% CisBP GCTGTACCTGCTTATTAGGC 54.3% identity Open · Scan
M08342_2.00 NN 70-40% CisBP GCTCTGCCTCCCTCT 53.6% identity Open · Scan
M08371_2.00 NN 70-40% CisBP CCAGACTTGTCCTCT 53.3% identity Open · Scan
M08540_2.00 NN 70-40% CisBP CCCCT 53.3% identity Open · Scan
M07717_2.00 NN 70-40% CisBP GGCTCCGCCCCC 53.2% identity Open · Scan
M08366_2.00 NN 70-40% CisBP GTTTGCTGCTTACAA 53.1% identity Open · Scan
M08335_2.00 NN 70-40% CisBP AGTCGTTGTCTG 52.9% identity Open · Scan
M07770_2.00 NN 70-40% CisBP CTTGGACTT 52.8% identity Open · Scan
M07659_2.00 NN 70-40% CisBP GTCTTCCAAGTAGCTGGTGTT 52.7% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 52.4% identity Open · Scan
M08367_2.00 NN 70-40% CisBP GGGGTGATGACCACTCTGGCTTCTTAC 52.3% identity Open · Scan
M07761_2.00 NN 70-40% CisBP CTGATTATTCACCCA 52.1% identity Open · Scan
M08247_2.00 NN 70-40% CisBP AAAAATAACAAACGG 52.0% identity Open · Scan
MA1594.1 NN 70-40% JASPAR AGGGGACATCACTACAGATCCCAC 52.0% identity Open · Scan
M06179_2.00 NN 70-40% CisBP TAAGCCTATAGA 51.8% identity Open · Scan
M07627_2.00 NN 70-40% CisBP CAGTCACCTTCTGG 51.8% identity Open · Scan
M08254_2.00 NN 70-40% CisBP CTGCCCTGGGACTTT 51.7% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 51.6% identity Open · Scan
M07648_2.00 NN 70-40% CisBP GCTTGCAAAAAAAATTTAACTCCCAGCTC 51.3% identity Open · Scan
M07714_2.00 NN 70-40% CisBP AGCCCATTGGGGCCTATGCCC 51.3% identity Open · Scan
M08255_2.00 NN 70-40% CisBP CTCTTCCGGT 50.8% identity Open · Scan
M06466_2.00 NN 70-40% CisBP TCCGCCCCCT 50.7% identity Open · Scan
M07686_2.00 NN 70-40% CisBP TAGCTTGTTTCCAGCCAC 50.4% identity Open · Scan
M08386_2.00 NN 70-40% CisBP GCCTTAAAAGCTCAGCAC 50.4% identity Open · Scan
M04621_2.00 NN 70-40% CisBP AGCAATTCCGCTCA 50.2% identity Open · Scan
M05855_2.00 NN 70-40% CisBP GTATTATACCCAGCT 50.2% identity Open · Scan
MA1589.1 NN 70-40% JASPAR TAGGAGTGGAATTGCTGGGTC 50.2% identity Open · Scan
M08887_2.00 NN 70-40% CisBP CCTCCTCCAGGAAGCCTTCCCTGA 50.1% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 50.0% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 50.0% identity Open · Scan
M08860_2.00 NN 70-40% CisBP TCTTATAAGGGCACTAATCCCATT 50.0% identity Open · Scan
ModCRE5
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_A8K8U0_A8K8U0_HUMAN:235:283_1llm_D_1 ModCRE Homology model CCCCGGCCCGGG Region 235-283 · 1 3D model Open · Scan
TFS_tr_A8K8U0_A8K8U0_HUMAN:143:287_2i13_A_1 ModCRE Homology model GAAAACTAGAAGTAGTTACAG Region 143-287 · 1 3D model Open · Scan
TFS_tr_A8K8U0_A8K8U0_HUMAN:65:288_5wjq_D_1 ModCRE Homology model TGGGCCCGGGGGGGTCCTGGAGAGTGCG Region 65-288 · 1 3D model Open · Scan
TFS_tr_A8K8U0_A8K8U0_HUMAN:68:292_5v3j_E_1 ModCRE Homology model CGGGGGGGCACGGGGGGACAAT Region 68-292 · 1 3D model Open · Scan
TFS_tr_A8K8U0_A8K8U0_HUMAN:68:292_5v3m_C_1 ModCRE Homology model AGGCGCCGGGGGGTGGATCTCG Region 68-292 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 306 aa
65-292

Region 65-292 5 PWM

Residues
228 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF13912 · C2H2-type zinc finger PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
6 active PDB models 6 summary rows
Region 65-2926 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_A8K8U0_A8K8U0_HUMAN:235:283_1llm_D_1 1llm 235-283 View model · PDB
Predicted = Low TFS_tr_A8K8U0_A8K8U0_HUMAN:143:287_2i13_A_1 2i13 143-287 View model · PDB
Predicted = Low TFS_tr_A8K8U0_A8K8U0_HUMAN:65:288_5wjq_D_1 5wjq 65-288 View model · PDB
Predicted = Low TFS_tr_A8K8U0_A8K8U0_HUMAN:66:292_7w1m_H_1 7w1m 66-292 View model · PDB
Predicted = Low TFS_tr_A8K8U0_A8K8U0_HUMAN:68:292_5v3j_E_1 5v3j 68-292 View model · PDB
Predicted = Low TFS_tr_A8K8U0_A8K8U0_HUMAN:68:292_5v3m_C_1 5v3m 68-292 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 2i13 65:292 143 287 P:A · DNA:C,D 56.6% / 73.1% 94 View · PDB TFS_tr_A8K8U0_A8K8U0_HUMAN:143:287_2i13_A_1
1 5wjq 65:292 65 288 P:D · DNA:A,B 46.4% / 65.6% 79 View · PDB TFS_tr_A8K8U0_A8K8U0_HUMAN:65:288_5wjq_D_1
2 5v3m 65:292 68 292 P:C · DNA:A,B 46.2% / 66.2% 81 View · PDB TFS_tr_A8K8U0_A8K8U0_HUMAN:68:292_5v3m_C_1
3 5v3j 65:292 68 292 P:E · DNA:A,B 46.2% / 66.2% 81 View · PDB TFS_tr_A8K8U0_A8K8U0_HUMAN:68:292_5v3j_E_1
1 1llm 65:292 235,235 283,283 P:C,D · DNA:A,B 44.9% / 63.3% 56,57 View · PDB DIMER_tr_A8K8U0_A8K8U0_HUMAN:235:283_1llm_D_1
5 7w1m 65:292 66 292 P:H · DNA:F,G 33.2% / 50.9% 70 View · PDB TFS_tr_A8K8U0_A8K8U0_HUMAN:66:292_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
97-119PF00096Zinc finger, C2H2 typeoverlaps 65-292
153-175PF00096Zinc finger, C2H2 typeoverlaps 65-292
181-203PF13912C2H2-type zinc fingeroverlaps 65-292
209-231PF00096Zinc finger, C2H2 typeoverlaps 65-292
237-259PF00096Zinc finger, C2H2 typeoverlaps 65-292