ModCRE DB

Transcription factor

A8KAF4

Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 594 aa

30 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)2
MotifPredictionSourceDNA bindingSupportLogoActions
MA0112.1 NN 70+% JASPAR CCAGGTCACCGTGACCCC 99.6% identity Open · Scan
M09309_2.00 NN 70+% CisBP AGGTCAGGGTGACCT 88.6% identity Open · Scan
Nearest Neighbor (70% - 40%)28
MotifPredictionSourceDNA bindingSupportLogoActions
M09275_2.00 NN 70-40% CisBP GGGTCACTTCAGGTCAG 60.0% identity Open · Scan
MA0258.1 NN 70-40% JASPAR CAAGGTCACGGTGACCTG 59.2% identity Open · Scan
M02392_2.00 NN 70-40% CisBP GAGGTCAA 56.1% identity Open · Scan
M03923_2.00 NN 70-40% CisBP AGAACACTGTGTACC 55.0% identity Open · Scan
M06417_2.00 NN 70-40% CisBP CAGTCCGAAGGTCACCGC 55.0% identity Open · Scan
MA0071.1 NN 70-40% JASPAR ATCAAGGTCA 54.5% identity Open · Scan
M01298_2.00 NN 70-40% CisBP AAAGGTCA 54.1% identity Open · Scan
M03927_2.00 NN 70-40% CisBP GAAACTAGAGCA 53.1% identity Open · Scan
M00812_2.00 NN 70-40% CisBP AGAGGTCACG 53.0% identity Open · Scan
M00820_2.00 NN 70-40% CisBP TAGGTCACC 53.0% identity Open · Scan
M05599_2.00 NN 70-40% CisBP AAAGGTCAA 53.0% identity Open · Scan
MA1150.1 NN 70-40% JASPAR AATTAGGTCAC 53.0% identity Open · Scan
MA1535.1 NN 70-40% JASPAR CGAGGTCAC 53.0% identity Open · Scan
MA1574.1 NN 70-40% JASPAR GGGGTCAAAGGTCAT 52.9% identity Open · Scan
M02409_2.00 NN 70-40% CisBP GAGATCAA 52.1% identity Open · Scan
M06432_2.00 NN 70-40% CisBP AAAAATCAAAGGT 52.1% identity Open · Scan
M05669_2.00 NN 70-40% CisBP GAGGTCAT 51.9% identity Open · Scan
MA0504.1 NN 70-40% JASPAR AGGGGTCAGAGGTCA 51.9% identity Open · Scan
M05635_2.00 NN 70-40% CisBP GTGACCTCAATGAGGTCAC 51.7% identity Open · Scan
MA1148.1 NN 70-40% JASPAR ATGTAGGTCAAAGGTCAT 51.5% identity Open · Scan
M02408_2.00 NN 70-40% CisBP TGAGGTCAATTT 51.2% identity Open · Scan
M09283_2.00 NN 70-40% CisBP TGAGGTCAAAAAAGTTCAG 50.7% identity Open · Scan
MA1533.1 NN 70-40% JASPAR ATGAACTCGATGAACTC 50.7% identity Open · Scan
M00690_2.00 NN 70-40% CisBP AAAGATCAAA 50.0% identity Open · Scan
M02413_2.00 NN 70-40% CisBP CGAGATCAA 50.0% identity Open · Scan
M03426_2.00 NN 70-40% CisBP GGGGTCAAAGTCCAAT 50.0% identity Open · Scan
M03928_2.00 NN 70-40% CisBP ATGTAGGTCAAG 50.0% identity Open · Scan
MA1151.1 NN 70-40% JASPAR ATAAGTAGGTCA 50.0% identity Open · Scan
ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 594 aa
180-250

Region 180-250 0 PWM

Residues
71 aa
Domains
PF02159 · Oestrogen receptor PF00105 · Double treble clef zinc finger, C4 type
3D models
1 active PDB
Templates
4OLN
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 180-2501 model
Actions
Predicted = Low DIMER_A8KAF4:180:250_4oln_A_1 4oln 180-250 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
42-181PF02159Oestrogen receptoroverlaps 180-250
184-252PF00105Double treble clef zinc finger, C4 typeoverlaps 180-250
336-529PF00104Ligand-binding domain of nuclear hormone receptorNo overlap with loaded model regions
551-594PF12743Oestrogen-type nuclear receptor final C-terminalNo overlap with loaded model regions