ModCRE DB

Transcription factor

A8MYV6 - HIF1A

Hypoxia-inducible factor 1-alpha

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 827 aa

3 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)2
MotifPredictionSourceDNA bindingSupportLogoActions
M08713_2.00 NN 70+% CisBP GGACGTGC 99.7% identity Open · Scan
MA0259.1 NN 70+% JASPAR GGACGTGC 99.7% identity Open · Scan
Nearest Neighbor (70% - 40%)1
MotifPredictionSourceDNA bindingSupportLogoActions
M09455_2.00 NN 70-40% CisBP GCACGTACCC 65.3% identity Open · Scan
ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 827 aa
20-69

Region 20-69 0 PWM

Residues
50 aa
Domains
PF23171 · Hypoxia-inducible factor 1-alpha bHLH domain
3D models
1 active PDB
Templates
4H10
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 20-691 model
Actions
Predicted = Low DIMER_A8MYV6:20:69_4h10_A_1 4h10 20-69 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
1-81PF23171Hypoxia-inducible factor 1-alpha bHLH domainoverlaps 20-69
95-150PF00989PAS foldNo overlap with loaded model regions
255-340PF08447PAS foldNo overlap with loaded model regions
556-581PF11413Hypoxia-inducible factor-1No overlap with loaded model regions
791-826PF08778HIF-1 alpha C terminal transactivation domainNo overlap with loaded model regions