ModCRE DB

Transcription factor

A8MZ59 - LEUTX

Paired-like homeodomain transcription factor LEUTX (Leucine-twenty homeobox) (Paired-like homeobox transcription factor LEUTX) (PRD-LIKE homeobox transcription factor LEUTX)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 198 aa

7 Generated PWM 12 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE7
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_A8MZ59_LEUTX_HUMAN:10:65_1hdd_D_1 ModCRE Homology model CCCCCTTAATTATTTAA Region 10-65 · 1 3D model Open · Scan
DIMER_sp_A8MZ59_LEUTX_HUMAN:10:65_3hdd_B_1 ModCRE Homology model CCCCCTTAATTATTTAA Region 10-65 · 1 3D model Open · Scan
DIMER_sp_A8MZ59_LEUTX_HUMAN:7:66_1fjl_A_1 ModCRE Homology model GTGATTCAATTAC Region 7-66 · 1 3D model Open · Scan
DIMER_sp_A8MZ59_LEUTX_HUMAN:9:64_2hdd_B_1 ModCRE Homology model CCCCCAAAATTGTTTAA Region 9-64 · 1 3D model Open · Scan
DIMER_sp_A8MZ59_LEUTX_HUMAN:9:65_3a01_B_1 ModCRE Homology model AATTAATTAATTGGGGC Region 9-65 · 1 3D model Open · Scan
DIMER_sp_A8MZ59_LEUTX_HUMAN:9:65_5hod_A_1 ModCRE Homology model ACAAATATATTTAATTAG Region 9-65 · 1 3D model Open · Scan
TFS_sp_A8MZ59_LEUTX_HUMAN:9:65_5hod_A_1 ModCRE Homology model ACCAATTTAATTGT Region 9-65 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 198 aa
5-70

Region 5-70 7 PWM

Residues
66 aa
Domains
PF00046 · Homeodomain
3D models
12 active PDBs · 10 summary rows
Templates
1FJL, 1HDD, 2HDD, 2LKX, 2ME6, 3A01, 3CMY, 3HDD, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
12 active PDB models 10 summary rows
Region 5-7012 models · 10 summary rows
Actions
Predicted = Low DIMER_sp_A8MZ59_LEUTX_HUMAN:10:65_1hdd_D_1 1hdd 10-65 View model · PDB
Predicted = Low DIMER_sp_A8MZ59_LEUTX_HUMAN:10:65_3hdd_B_1 3hdd 10-65 View model · PDB
Predicted = Low DIMER_sp_A8MZ59_LEUTX_HUMAN:7:66_1fjl_A_1 1fjl 7-66 View model · PDB
Predicted = Low DIMER_sp_A8MZ59_LEUTX_HUMAN:9:64_2hdd_B_1 2hdd 9-64 View model · PDB
Predicted = Low DIMER_sp_A8MZ59_LEUTX_HUMAN:9:65_3a01_B_1 3a01 9-65 View model · PDB
Predicted = Low DIMER_sp_A8MZ59_LEUTX_HUMAN:9:65_5hod_A_1 5hod 9-65 View model · PDB
Predicted = Low TFS_sp_A8MZ59_LEUTX_HUMAN:10:67_3lnq_A_1 3lnq 10-67 View model · PDB
Predicted = Low TFS_sp_A8MZ59_LEUTX_HUMAN:9:65_2me6_A_1 2me6 9-65 View model · PDB
Predicted = Low TFS_sp_A8MZ59_LEUTX_HUMAN:9:65_3a01_B_1 3a01 9-65 View model · PDB
Predicted = Low TFS_sp_A8MZ59_LEUTX_HUMAN:9:65_5hod_A_1 5hod 9-65 View model · PDB
Predicted = Low TFS_sp_A8MZ59_LEUTX_HUMAN:9:66_3cmy_A_1 3cmy 9-66 View model · PDB
Predicted = Low TFS_sp_A8MZ59_LEUTX_HUMAN:9:67_2lkx_A_1 2lkx 9-67 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
5 2me6 4:75 9 65 P:A · DNA:B,C 45.6% / 59.6% 80 View · PDB TFS_sp_A8MZ59_LEUTX_HUMAN:9:65_2me6_A_1
4 2hdd 4:75 12,9 65,64 P:A,B · DNA:C,D 41.1% / 64.3% 98,100 View · PDB DIMER_sp_A8MZ59_LEUTX_HUMAN:9:64_2hdd_B_1
1 3a01 4:75 5,9 70,65 P:A,B · DNA:C,D 40.4% / 64.9% 84,100 View · PDB DIMER_sp_A8MZ59_LEUTX_HUMAN:9:65_3a01_B_1
2 5hod 4:75 9,10 65,65 P:A,D · DNA:B,C 40.4% / 64.9% 93,96 View · PDB DIMER_sp_A8MZ59_LEUTX_HUMAN:9:65_5hod_A_1
4 3a01 4:75 5,9 70,65 P:A,B · DNA:C,D 40.4% / 64.9% 84,100 View · PDB TFS_sp_A8MZ59_LEUTX_HUMAN:9:65_3a01_B_1
1 3cmy 4:75 9 66 P:A · DNA:B,C 39.7% / 65.5% 96 View · PDB TFS_sp_A8MZ59_LEUTX_HUMAN:9:66_3cmy_A_1
3 3lnq 4:75 10 67 P:A · DNA:B,C 39.7% / 65.5% 100 View · PDB TFS_sp_A8MZ59_LEUTX_HUMAN:10:67_3lnq_A_1
5 1hdd 4:75 10,10 65,65 P:C,D · DNA:A,B 39.3% / 64.3% 98,98 View · PDB DIMER_sp_A8MZ59_LEUTX_HUMAN:10:65_1hdd_D_1
2 2lkx 4:75 9 67 P:A · DNA:B,C 37.3% / 64.4% 86 View · PDB TFS_sp_A8MZ59_LEUTX_HUMAN:9:67_2lkx_A_1
3 1fjl 4:75 7,9 66,62 P:A,B · DNA:D,E 35.0% / 61.7% 92,94 View · PDB DIMER_sp_A8MZ59_LEUTX_HUMAN:7:66_1fjl_A_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
9-65PF00046Homeodomainoverlaps 5-70