ModCRE DB

Transcription factor

B0QYW7 - ESR1

Estrogen receptor 1

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 107 aa

74 Generated PWM 11 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)63
MotifPredictionSourceDNA bindingSupportLogoActions
MA0007.1 NN 70-40% JASPAR ATAAGAACACCCTGTACCCGCC 65.7% identity Open · Scan
MA0007.2 NN 70-40% JASPAR AAGAACAGAATGTTC 65.7% identity Open · Scan
MA0007.3 NN 70-40% JASPAR GGGAACACGGTGTACCC 65.7% identity Open · Scan
MA0592.1 NN 70-40% JASPAR CCAAGGTCACA 62.1% identity Open · Scan
MA0592.2 NN 70-40% JASPAR TTCAAGGTCAT 62.1% identity Open · Scan
M09283_2.00 NN 70-40% CisBP TGAGGTCAAAAAAGTTCAG 61.5% identity Open · Scan
MA1533.1 NN 70-40% JASPAR ATGAACTCGATGAACTC 61.5% identity Open · Scan
M00371_2.00 NN 70-40% CisBP ACTTAATATATAC 58.3% identity Open · Scan
MA0164.1 NN 70-40% JASPAR CAAGCTT 58.3% identity Open · Scan
M00811_2.00 NN 70-40% CisBP AAAGGTCAAG 57.6% identity Open · Scan
M03382_2.00 NN 70-40% CisBP GGGAACACAATGTTCCC 57.5% identity Open · Scan
M05886_2.00 NN 70-40% CisBP AGTACATTTTGTTCT 57.5% identity Open · Scan
M07987_2.00 NN 70-40% CisBP GCCCAGAACATTCTGTTCCCT 57.5% identity Open · Scan
MA0113.1 NN 70-40% JASPAR GGGAACATTATGTCCTAA 57.5% identity Open · Scan
MA0727.1 NN 70-40% JASPAR GGGAACACAATGTTCCC 57.5% identity Open · Scan
M06417_2.00 NN 70-40% CisBP CAGTCCGAAGGTCACCGC 56.2% identity Open · Scan
M02408_2.00 NN 70-40% CisBP TGAGGTCAATTT 55.5% identity Open · Scan
M02409_2.00 NN 70-40% CisBP GAGATCAA 54.2% identity Open · Scan
M06432_2.00 NN 70-40% CisBP AAAAATCAAAGGT 54.2% identity Open · Scan
M00822_2.00 NN 70-40% CisBP GAGGTCAC 53.1% identity Open · Scan
M02393_2.00 NN 70-40% CisBP AGAGGTCAC 53.1% identity Open · Scan
M05661_2.00 NN 70-40% CisBP GGGGTCAAAGGTCAG 53.1% identity Open · Scan
MA0017.1 NN 70-40% JASPAR TGACCTTTGAACCT 53.1% identity Open · Scan
MA0071.1 NN 70-40% JASPAR ATCAAGGTCA 53.1% identity Open · Scan
MA1111.1 NN 70-40% JASPAR CAAAGGTCAAA 53.1% identity Open · Scan
M01298_2.00 NN 70-40% CisBP AAAGGTCA 52.9% identity Open · Scan
M02389_2.00 NN 70-40% CisBP CAGGTCACT 52.9% identity Open · Scan
M03392_2.00 NN 70-40% CisBP AAGGTCAACTAAAGGTCA 52.9% identity Open · Scan
M03424_2.00 NN 70-40% CisBP AAAGGTCACCAGAGGTCA 52.9% identity Open · Scan
M03927_2.00 NN 70-40% CisBP GAAACTAGAGCA 52.9% identity Open · Scan
M03939_2.00 NN 70-40% CisBP TAAAGGTCA 52.9% identity Open · Scan
M05563_2.00 NN 70-40% CisBP AAAAGGTCAA 52.9% identity Open · Scan
M05604_2.00 NN 70-40% CisBP TAAAGGTCAC 52.9% identity Open · Scan
M09277_2.00 NN 70-40% CisBP GGGGGATCAAGAGGTCAAGG 52.9% identity Open · Scan
MA0159.1 NN 70-40% JASPAR AGGTCACGGAGAGGTCA 52.9% identity Open · Scan
MA0160.1 NN 70-40% JASPAR AAGGTCAC 52.9% identity Open · Scan
MA0857.1 NN 70-40% JASPAR AAAGGTCAAAAGGTCA 52.9% identity Open · Scan
MA0859.1 NN 70-40% JASPAR AAGGTCAAAAGGTCAA 52.9% identity Open · Scan
MA1112.1 NN 70-40% JASPAR AAAAGGTCAC 52.9% identity Open · Scan
MA1552.1 NN 70-40% JASPAR AAGGTCATGACCTT 52.9% identity Open · Scan
MA1553.1 NN 70-40% JASPAR AAGGTCATGACCTT 52.9% identity Open · Scan
M00814_2.00 NN 70-40% CisBP AAAGTCAAAT 52.7% identity Open · Scan
MA0676.1 NN 70-40% JASPAR AAAAGTCAA 52.7% identity Open · Scan
M00820_2.00 NN 70-40% CisBP TAGGTCACC 50.0% identity Open · Scan
M03432_2.00 NN 70-40% CisBP AAAGGTCAAGAGAGGTCA 50.0% identity Open · Scan
M03928_2.00 NN 70-40% CisBP ATGTAGGTCAAG 50.0% identity Open · Scan
M03930_2.00 NN 70-40% CisBP AACTAGAGCAC 50.0% identity Open · Scan
M05590_2.00 NN 70-40% CisBP TTCAAGGTCAC 50.0% identity Open · Scan
M05669_2.00 NN 70-40% CisBP GAGGTCAT 50.0% identity Open · Scan
M09616_2.00 NN 70-40% CisBP TTCAAGGTCA 50.0% identity Open · Scan
M11139_2.00 NN 70-40% CisBP AAGTAGGTCACCGTGACCTACTT 50.0% identity Open · Scan
MA0065.1 NN 70-40% JASPAR CCAGGGGTCAAAGGTCATCG 50.0% identity Open · Scan
MA0065.2 NN 70-40% JASPAR GTAGGGCAAAGGTCA 50.0% identity Open · Scan
MA0074.1 NN 70-40% JASPAR GGGTCAACGAGTTCA 50.0% identity Open · Scan
MA0115.1 NN 70-40% JASPAR AAAGGTCAAAGGTCAAC 50.0% identity Open · Scan
MA0484.1 NN 70-40% JASPAR AGAGTCCAAAGTCCA 50.0% identity Open · Scan
MA0504.1 NN 70-40% JASPAR AGGGGTCAGAGGTCA 50.0% identity Open · Scan
MA0505.1 NN 70-40% JASPAR AAGTTCAAGGTCAGC 50.0% identity Open · Scan
MA0677.1 NN 70-40% JASPAR GAGGTCAAAGGTCA 50.0% identity Open · Scan
MA0693.1 NN 70-40% JASPAR GAGTTCATTGAGTTCA 50.0% identity Open · Scan
MA1150.1 NN 70-40% JASPAR AATTAGGTCAC 50.0% identity Open · Scan
MA1539.1 NN 70-40% JASPAR AAGGTCACTGACCTT 50.0% identity Open · Scan
MA1540.1 NN 70-40% JASPAR GTCAAGGTCAC 50.0% identity Open · Scan
ModCRE11
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_B0QYW7_B0QYW7_HUMAN:1:36_4aa6_A_1 ModCRE Homology model AGGGTCAATTTGACCCG Region 1-36 · 1 3D model Open · Scan
DIMER_tr_B0QYW7_B0QYW7_HUMAN:1:37_1hcq_B_1 ModCRE Homology model ATGGTCAAGTTGACCTT Region 1-37 · 1 3D model Open · Scan
DIMER_tr_B0QYW7_B0QYW7_HUMAN:2:39_2c7a_A_1 ModCRE Homology model AAATAACAATGTACCTT Region 2-39 · 1 3D model Open · Scan
DIMER_tr_B0QYW7_B0QYW7_HUMAN:3:35_4oln_B_1 ModCRE Homology model CGGGGTCAATTTTACCTAC Region 3-35 · 1 3D model Open · Scan
DIMER_tr_B0QYW7_B0QYW7_HUMAN:3:39_8ifo_A_1 ModCRE Homology model CTTGTACCTTTGACCTA Region 3-39 · 1 3D model Open · Scan
DIMER_tr_B0QYW7_B0QYW7_HUMAN:4:38_1r4i_B_1 ModCRE Homology model AAGGTCAATTGAACCTCC Region 4-38 · 1 3D model Open · Scan
TFS_tr_B0QYW7_B0QYW7_HUMAN:1:36_4aa6_A_1 ModCRE Homology model AGGGTCAATTTGACCCG Region 1-36 · 1 3D model Open · Scan
TFS_tr_B0QYW7_B0QYW7_HUMAN:1:37_1hcq_B_1 ModCRE Homology model TTGGTCAAGTTGACCTC Region 1-37 · 1 3D model Open · Scan
TFS_tr_B0QYW7_B0QYW7_HUMAN:3:39_1lo1_A_1 ModCRE Homology model GTGGTCCTTTAGG Region 3-39 · 1 3D model Open · Scan
TFS_tr_B0QYW7_B0QYW7_HUMAN:3:39_8ifo_A_1 ModCRE Homology model TTTGTACCTTTGACCTT Region 3-39 · 1 3D model Open · Scan
TFS_tr_B0QYW7_B0QYW7_HUMAN:4:38_1r4i_B_1 ModCRE Homology model AAGGTCAATTGACCCCCC Region 4-38 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 107 aa
1-39

Region 1-39 11 PWM

Residues
39 aa
Domains
PF00105 · Double treble clef zinc finger, C4 type PF00104 · Ligand-binding domain of nuclear hormone receptor
3D models
11 active PDBs · 10 summary rows
Templates
1HCQ, 1LO1, 1R4I, 2C7A, 4AA6, 4OLN, 8IFO
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
11 active PDB models 10 summary rows
Region 1-3911 models · 10 summary rows
Actions
Predicted = Low DIMER_tr_B0QYW7_B0QYW7_HUMAN:1:36_4aa6_A_1 4aa6 1-36 View model · PDB
Predicted = Low DIMER_tr_B0QYW7_B0QYW7_HUMAN:1:37_1hcq_B_1 1hcq 1-37 View model · PDB
Predicted = Low DIMER_tr_B0QYW7_B0QYW7_HUMAN:2:39_2c7a_A_1 2c7a 2-39 View model · PDB
Predicted = Low DIMER_tr_B0QYW7_B0QYW7_HUMAN:3:35_4oln_B_1 4oln 3-35 View model · PDB
Predicted = Low DIMER_tr_B0QYW7_B0QYW7_HUMAN:3:39_8ifo_A_1 8ifo 3-39 View model · PDB
Predicted = Low DIMER_tr_B0QYW7_B0QYW7_HUMAN:4:38_1r4i_B_1 1r4i 4-38 View model · PDB
Predicted = Low TFS_tr_B0QYW7_B0QYW7_HUMAN:1:36_4aa6_A_1 4aa6 1-36 View model · PDB
Predicted = Low TFS_tr_B0QYW7_B0QYW7_HUMAN:1:37_1hcq_B_1 1hcq 1-37 View model · PDB
Predicted = Low TFS_tr_B0QYW7_B0QYW7_HUMAN:3:39_1lo1_A_1 1lo1 3-39 View model · PDB
Predicted = Low TFS_tr_B0QYW7_B0QYW7_HUMAN:3:39_8ifo_A_1 8ifo 3-39 View model · PDB
Predicted = Low TFS_tr_B0QYW7_B0QYW7_HUMAN:4:38_1r4i_B_1 1r4i 4-38 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 1hcq 1:39 1,1 37,37 P:A,B · DNA:C,D 100.0% / 100.0% 50,52 View · PDB DIMER_tr_B0QYW7_B0QYW7_HUMAN:1:37_1hcq_B_1
1 1hcq 1:39 1,1 37,37 P:A,B · DNA:C,D 100.0% / 100.0% 50,52 View · PDB TFS_tr_B0QYW7_B0QYW7_HUMAN:1:37_1hcq_B_1
2 4aa6 1:39 1,1 36,36 P:A,B · DNA:C,D 100.0% / 100.0% 52,50 View · PDB DIMER_tr_B0QYW7_B0QYW7_HUMAN:1:36_4aa6_A_1
2 4aa6 1:39 1,1 36,36 P:A,B · DNA:C,D 100.0% / 100.0% 52,50 View · PDB TFS_tr_B0QYW7_B0QYW7_HUMAN:1:36_4aa6_A_1
3 8ifo 1:39 3,3 39,39 P:A,B · DNA:C,D 67.6% / 78.4% 48,46 View · PDB DIMER_tr_B0QYW7_B0QYW7_HUMAN:3:39_8ifo_A_1
3 8ifo 1:39 3,3 39,39 P:A,B · DNA:C,D 67.6% / 78.4% 48,46 View · PDB TFS_tr_B0QYW7_B0QYW7_HUMAN:3:39_8ifo_A_1
4 1r4i 1:39 4,4 38,38 P:A,B · DNA:C,D 65.7% / 77.1% 47,49 View · PDB DIMER_tr_B0QYW7_B0QYW7_HUMAN:4:38_1r4i_B_1
5 1r4i 1:39 4,4 38,38 P:A,B · DNA:C,D 65.7% / 77.1% 47,49 View · PDB TFS_tr_B0QYW7_B0QYW7_HUMAN:4:38_1r4i_B_1
4 1lo1 1:39 3 39 P:A · DNA:B,C 64.9% / 75.7% 41 View · PDB TFS_tr_B0QYW7_B0QYW7_HUMAN:3:39_1lo1_A_1
5 2c7a 1:39 2,2 39,39 P:A,B · DNA:C,D 55.3% / 73.7% 48,50 View · PDB DIMER_tr_B0QYW7_B0QYW7_HUMAN:2:39_2c7a_A_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
2-37PF00105Double treble clef zinc finger, C4 typeoverlaps 1-39
39-88PF00104Ligand-binding domain of nuclear hormone receptoroverlaps 1-39