Transcription factor

B2R617

Hypoxia-inducible factor 1-alpha

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 826 aa

3 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)2

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M08713_2.00	NN 70+%	CisBP	GGACGTGC	99.8% identity		Open · Scan
MA0259.1	NN 70+%	JASPAR	GGACGTGC	99.8% identity		Open · Scan

Nearest Neighbor (70% - 40%)1

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M09455_2.00	NN 70-40%	CisBP	GCACGTACCC	66.0% identity		Open · Scan

ModCRE0

No generated PWM in this category.

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 826 aa

19-68

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

1 active PDB model

Region 19-681 model

				Actions
Predicted = Low	DIMER_B2R617:19:68_4h10_A_1	4h10	19-68	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
1-80	PF23171	Hypoxia-inducible factor 1-alpha bHLH domain	overlaps 19-68
94-149	PF00989	PAS fold	No overlap with loaded model regions
254-339	PF08447	PAS fold	No overlap with loaded model regions
555-580	PF11413	Hypoxia-inducible factor-1	No overlap with loaded model regions
790-825	PF08778	HIF-1 alpha C terminal transactivation domain	No overlap with loaded model regions