ModCRE DB

Transcription factor

B2RXF5 - ZBTB42

Zinc finger and BTB domain-containing protein 42

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 422 aa

19 Generated PWM 11 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1
MotifPredictionSourceDNA bindingSupportLogoActions
M08351_2.00 Known CisBP CACAGCTGG Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)12
MotifPredictionSourceDNA bindingSupportLogoActions
M00943_2.00 NN 70-40% CisBP CCCGCTGC 58.6% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 57.3% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 56.0% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 54.6% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 54.6% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 54.6% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 53.3% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 53.3% identity Open · Scan
M00217_2.00 NN 70-40% CisBP TTACTCAATAT 51.3% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 50.6% identity Open · Scan
M08371_2.00 NN 70-40% CisBP CCAGACTTGTCCTCT 50.6% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 50.0% identity Open · Scan
ModCRE6
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_B2RXF5_ZBT42_HUMAN:360:408_1llm_C_1 ModCRE Homology model GCCGCGCGCGGC Region 360-408 · 1 3D model Open · Scan
TFS_sp_B2RXF5_ZBT42_HUMAN:336:386_5yj3_C_1 ModCRE Homology model CGCCA Region 336-386 · 1 3D model Open · Scan
TFS_sp_B2RXF5_ZBT42_HUMAN:339:410_1a1g_A_1 ModCRE Homology model GGGGGGGGCG Region 339-410 · 1 3D model Open · Scan
TFS_sp_B2RXF5_ZBT42_HUMAN:339:413_1tf3_A_1 ModCRE Homology model TTTGCCCCCTCGATT Region 339-413 · 1 3D model Open · Scan
TFS_sp_B2RXF5_ZBT42_HUMAN:360:410_1f2i_G_1 ModCRE Homology model CGCGAGTTAAG Region 360-410 · 1 3D model Open · Scan
TFS_sp_B2RXF5_ZBT42_HUMAN:360:410_1f2i_H_1 ModCRE Homology model TGGAACTCGCG Region 360-410 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 422 aa
336-414

Region 336-414 6 PWM

Residues
79 aa
Domains
PF13894 · C2H2-type zinc finger PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
11 active PDBs · 6 summary rows
Templates
1A1G, 1F2I, 1LLM, 1TF3, 2KMK, 5YJ3, 7N5S, 7N5T, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
11 active PDB models 6 summary rows
Region 336-41411 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_B2RXF5_ZBT42_HUMAN:360:408_1llm_C_1 1llm 360-408 View model · PDB
Predicted = Low TFS_sp_B2RXF5_ZBT42_HUMAN:336:386_5yj3_C_1 5yj3 336-386 View model · PDB
Predicted = Low TFS_sp_B2RXF5_ZBT42_HUMAN:336:411_2kmk_A_1 2kmk 336-411 View model · PDB
Predicted = Low TFS_sp_B2RXF5_ZBT42_HUMAN:336:414_7n5s_A_1 7n5s 336-414 View model · PDB
Predicted = Low TFS_sp_B2RXF5_ZBT42_HUMAN:336:414_7n5t_A_1 7n5t 336-414 View model · PDB
Predicted = Low TFS_sp_B2RXF5_ZBT42_HUMAN:336:414_8e3d_A_1 8e3d 336-414 View model · PDB
Predicted = Low TFS_sp_B2RXF5_ZBT42_HUMAN:336:414_8e3e_A_1 8e3e 336-414 View model · PDB
Predicted = Low TFS_sp_B2RXF5_ZBT42_HUMAN:339:410_1a1g_A_1 1a1g 339-410 View model · PDB
Predicted = Low TFS_sp_B2RXF5_ZBT42_HUMAN:339:413_1tf3_A_1 1tf3 339-413 View model · PDB
Predicted = Low TFS_sp_B2RXF5_ZBT42_HUMAN:360:410_1f2i_G_1 1f2i 360-410 View model · PDB
Predicted = Low TFS_sp_B2RXF5_ZBT42_HUMAN:360:410_1f2i_H_1 1f2i 360-410 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 2kmk 317:414 336 411 P:A · DNA:B,C 44.7% / 60.5% 93 View · PDB TFS_sp_B2RXF5_ZBT42_HUMAN:336:411_2kmk_A_1
1 1llm 317:414 360,360 408,408 P:C,D · DNA:A,B 42.9% / 59.2% 56,57 View · PDB DIMER_sp_B2RXF5_ZBT42_HUMAN:360:408_1llm_C_1
2 8e3e 317:414 336 414 P:A · DNA:X,Y 41.8% / 60.8% 71 View · PDB TFS_sp_B2RXF5_ZBT42_HUMAN:336:414_8e3e_A_1
3 8e3d 317:414 336 414 P:A · DNA:X,Y 41.8% / 60.8% 71 View · PDB TFS_sp_B2RXF5_ZBT42_HUMAN:336:414_8e3d_A_1
4 7n5t 317:414 336 414 P:A · DNA:X,Y 41.8% / 60.8% 71 View · PDB TFS_sp_B2RXF5_ZBT42_HUMAN:336:414_7n5t_A_1
5 7n5s 317:414 336 414 P:A · DNA:X,Y 41.8% / 60.8% 71 View · PDB TFS_sp_B2RXF5_ZBT42_HUMAN:336:414_7n5s_A_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
15-121PF00651BTB/POZ domainNo overlap with loaded model regions
335-356PF13894C2H2-type zinc fingeroverlaps 336-414
362-384PF00096Zinc finger, C2H2 typeoverlaps 336-414
390-413PF00096Zinc finger, C2H2 typeoverlaps 336-414