ModCRE DB

Transcription factor

B3KXP2

Transcription factor Sp6 (Krueppel-like factor 14)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 376 aa

60 Generated PWM 8 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)53
MotifPredictionSourceDNA bindingSupportLogoActions
MA0746.1 NN 70-40% JASPAR GCCACGCCCCC 67.2% identity Open · Scan
M04555_2.00 NN 70-40% CisBP GCCACGCCCCCGCCACGCCCAC 65.4% identity Open · Scan
M05859_2.00 NN 70-40% CisBP GGCCACGCCCACT 65.4% identity Open · Scan
MA0685.1 NN 70-40% JASPAR TAAGCCACGCCCCCTTT 65.4% identity Open · Scan
MA1512.1 NN 70-40% JASPAR GCCACGCCCAC 65.4% identity Open · Scan
M00765_2.00 NN 70-40% CisBP CCCGCCCCC 63.9% identity Open · Scan
MA0657.1 NN 70-40% JASPAR ATGCCACGCCCCTTTTTG 63.8% identity Open · Scan
M08246_2.00 NN 70-40% CisBP GCCCCACCCA 63.2% identity Open · Scan
MA1511.1 NN 70-40% JASPAR GCCACACCCCC 63.2% identity Open · Scan
M02903_2.00 NN 70-40% CisBP ATGCCACGCCCCTTTTTG 63.1% identity Open · Scan
MA0741.1 NN 70-40% JASPAR GCCACGCCCCC 62.3% identity Open · Scan
M00224_2.00 NN 70-40% CisBP CCCGCCCC 60.2% identity Open · Scan
M00617_2.00 NN 70-40% CisBP CCACGCCCA 60.2% identity Open · Scan
M00777_2.00 NN 70-40% CisBP ACCGTTAT 60.2% identity Open · Scan
MA0740.1 NN 70-40% JASPAR GGCCACGCCCCCTT 60.2% identity Open · Scan
MA1107.1 NN 70-40% JASPAR GGCCACACCCACC 60.2% identity Open · Scan
M06135_2.00 NN 70-40% CisBP CAGCCACGCCCACCT 59.7% identity Open · Scan
MA0599.1 NN 70-40% JASPAR GCCCCGCCCC 59.5% identity Open · Scan
M06466_2.00 NN 70-40% CisBP TCCGCCCCCT 59.4% identity Open · Scan
MA1515.1 NN 70-40% JASPAR CACCACGCCCA 59.0% identity Open · Scan
M00647_2.00 NN 70-40% CisBP CCCCCCC 58.9% identity Open · Scan
MA0079.1 NN 70-40% JASPAR GGGGCGGGGT 58.5% identity Open · Scan
MA1513.1 NN 70-40% JASPAR GCCCCGCCCCC 58.3% identity Open · Scan
M00954_2.00 NN 70-40% CisBP CTACCCTA 58.2% identity Open · Scan
M04463_2.00 NN 70-40% CisBP CACCACGCCCA 57.9% identity Open · Scan
M09008_2.00 NN 70-40% CisBP CCCGGCCCCACCCT 57.9% identity Open · Scan
MA0039.1 NN 70-40% JASPAR TAAAGGAAGG 57.9% identity Open · Scan
MA0039.3 NN 70-40% JASPAR CCACACCCTGC 57.9% identity Open · Scan
MA0493.1 NN 70-40% JASPAR GGCCACACCCA 57.9% identity Open · Scan
MA1517.1 NN 70-40% JASPAR GGCCACGCCCA 57.6% identity Open · Scan
M06122_2.00 NN 70-40% CisBP GATACGCCCCCTAA 56.0% identity Open · Scan
M00134_2.00 NN 70-40% CisBP GCCACGCCCA 55.5% identity Open · Scan
MA1514.1 NN 70-40% JASPAR CACCACGCACCCCTT 55.5% identity Open · Scan
M00632_2.00 NN 70-40% CisBP ACACGCCCCT 55.3% identity Open · Scan
M06169_2.00 NN 70-40% CisBP GCCACGCCCAAC 54.9% identity Open · Scan
MA0516.1 NN 70-40% JASPAR GCCCCGCCCCCTCCC 54.8% identity Open · Scan
M04430_2.00 NN 70-40% CisBP GACCACGCCCA 54.3% identity Open · Scan
MA0742.1 NN 70-40% JASPAR GACCACGCCCTTATT 54.3% identity Open · Scan
MA1516.1 NN 70-40% JASPAR GACCACGCCCA 54.3% identity Open · Scan
M00951_2.00 NN 70-40% CisBP GCTGCACG 53.8% identity Open · Scan
MA0834.1 NN 70-40% JASPAR CGATGACGTCATCG 52.9% identity Open · Scan
M00249_2.00 NN 70-40% CisBP ACTCCCCCGCA 51.8% identity Open · Scan
M08968_2.00 NN 70-40% CisBP CCCCCCCTCCTCCCCCGCCC 51.8% identity Open · Scan
MA1627.1 NN 70-40% JASPAR CCCCTCCCCCACAC 51.8% identity Open · Scan
M00779_2.00 NN 70-40% CisBP GCCACGCCCA 51.6% identity Open · Scan
M08867_2.00 NN 70-40% CisBP CACCCCCTG 51.6% identity Open · Scan
MA0747.1 NN 70-40% JASPAR GCCACGCCCACT 51.1% identity Open · Scan
M01039_2.00 NN 70-40% CisBP CCCCCTA 51.0% identity Open · Scan
M01032_2.00 NN 70-40% CisBP ACCCCTGA 50.0% identity Open · Scan
M01035_2.00 NN 70-40% CisBP CCCCCTTAAT 50.0% identity Open · Scan
M01180_2.00 NN 70-40% CisBP ACCCCTGG 50.0% identity Open · Scan
M03710_2.00 NN 70-40% CisBP CTCACGCCCCCC 50.0% identity Open · Scan
M08525_2.00 NN 70-40% CisBP CCCCGCA 50.0% identity Open · Scan
ModCRE7
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_tr_B3KXP2_B3KXP2_HUMAN:254:336_2wbs_A_1 ModCRE Homology model CGGCCCA Region 254-336 · 1 3D model Open · Scan
TFS_tr_B3KXP2_B3KXP2_HUMAN:254:336_2wbu_A_1 ModCRE Homology model GGGCGGGGCA Region 254-336 · 1 3D model Open · Scan
TFS_tr_B3KXP2_B3KXP2_HUMAN:254:336_4m9e_A_1 ModCRE Homology model GGGGCGCCCA Region 254-336 · 1 3D model Open · Scan
TFS_tr_B3KXP2_B3KXP2_HUMAN:254:336_5ke6_A_1 ModCRE Homology model GGCCGGGGCG Region 254-336 · 1 3D model Open · Scan
TFS_tr_B3KXP2_B3KXP2_HUMAN:254:336_5ke7_A_1 ModCRE Homology model GGGGGGGGCA Region 254-336 · 1 3D model Open · Scan
TFS_tr_B3KXP2_B3KXP2_HUMAN:254:336_5kea_A_1 ModCRE Homology model GGGGGGCGCA Region 254-336 · 1 3D model Open · Scan
TFS_tr_B3KXP2_B3KXP2_HUMAN:254:336_6vtx_A_1 ModCRE Homology model CGGGGGGGGGCA Region 254-336 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 376 aa
254-336

Region 254-336 7 PWM

Residues
83 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
8 active PDBs · 6 summary rows
Templates
1LLM, 2WBS, 2WBU, 4M9E, 5KE6, 5KE7, 5KEA, 6VTX
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
8 active PDB models 6 summary rows
Region 254-3368 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_B3KXP2_B3KXP2_HUMAN:282:332_1llm_D_1 1llm 282-332 View model · PDB
Predicted = Low TFS_tr_B3KXP2_B3KXP2_HUMAN:254:336_2wbs_A_1 2wbs 254-336 View model · PDB
Predicted = Low TFS_tr_B3KXP2_B3KXP2_HUMAN:254:336_2wbu_A_1 2wbu 254-336 View model · PDB
Predicted = Low TFS_tr_B3KXP2_B3KXP2_HUMAN:254:336_4m9e_A_1 4m9e 254-336 View model · PDB
Predicted = Low TFS_tr_B3KXP2_B3KXP2_HUMAN:254:336_5ke6_A_1 5ke6 254-336 View model · PDB
Predicted = Low TFS_tr_B3KXP2_B3KXP2_HUMAN:254:336_5ke7_A_1 5ke7 254-336 View model · PDB
Predicted = Low TFS_tr_B3KXP2_B3KXP2_HUMAN:254:336_5kea_A_1 5kea 254-336 View model · PDB
Predicted = Low TFS_tr_B3KXP2_B3KXP2_HUMAN:254:336_6vtx_A_1 6vtx 254-336 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 6vtx 230:343 254 336 P:A · DNA:B,C 60.2% / 71.1% 100 View · PDB TFS_tr_B3KXP2_B3KXP2_HUMAN:254:336_6vtx_A_1
2 5ke7 230:343 254 336 P:A · DNA:B,C 60.2% / 71.1% 95 View · PDB TFS_tr_B3KXP2_B3KXP2_HUMAN:254:336_5ke7_A_1
3 2wbs 230:343 254 336 P:A · DNA:F,G 60.2% / 71.1% 95 View · PDB TFS_tr_B3KXP2_B3KXP2_HUMAN:254:336_2wbs_A_1
4 5ke6 230:343 254 336 P:A · DNA:B,C 60.2% / 71.1% 97 View · PDB TFS_tr_B3KXP2_B3KXP2_HUMAN:254:336_5ke6_A_1
5 4m9e 230:343 254 336 P:A · DNA:B,C 60.2% / 71.1% 97 View · PDB TFS_tr_B3KXP2_B3KXP2_HUMAN:254:336_4m9e_A_1
1 1llm 230:343 282,282 332,332 P:C,D · DNA:A,B 47.1% / 60.8% 56,57 View · PDB DIMER_tr_B3KXP2_B3KXP2_HUMAN:282:332_1llm_D_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
254-278PF00096Zinc finger, C2H2 typeoverlaps 254-336
284-308PF00096Zinc finger, C2H2 typeoverlaps 254-336
314-336PF00096Zinc finger, C2H2 typeoverlaps 254-336