Transcription factor
B4DS34
Hypoxia-inducible factor 1-alpha
Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 767 aa
Motif Prediction
Only entries with a generated matrix are shown here.
Known0
No generated PWM in this category.
Nearest Neighbor (>70%)2
Nearest Neighbor (70% - 40%)1
| Motif | Prediction | Source | DNA binding | Support | Logo | Actions |
|---|---|---|---|---|---|---|
| M09455_2.00 | NN 70-40% | CisBP | GCACGTACCC | 61.0% identity | Open · Scan |
ModCRE0
No generated PWM in this category.
PWM available; no validated DNA-bound structure
Exact accession contains only 20.37% of the canonical HIF1A bHLH DNA-binding domain (100% identity). Other PAS/regulatory Pfam domains are present, but a complete DBD is not.
Domains
Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.
| Residues | PFAM | Domain |
|---|---|---|
| 35-90 | PF00989 | PAS fold |
| 195-280 | PF08447 | PAS fold |
| 496-521 | PF11413 | Hypoxia-inducible factor-1 |
| 731-766 | PF08778 | HIF-1 alpha C terminal transactivation domain |