Region 46-292 0 PWM
- Residues
- 247 aa
- Domains
- PF23171 · Hypoxia-inducible factor 1-alpha bHLH domain PF08447 · PAS fold
- 3D models
- 1 active PDB
- Templates
- 4ZPR
- Sources
- Structure model
Transcription factor
B4E2K5
Hypoxia-inducible factor 1-alpha
Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 769 aa
Motif Prediction
Only entries with a generated matrix are shown here.
Known0
No generated PWM in this category.
Nearest Neighbor (>70%)2
Nearest Neighbor (70% - 40%)1
| Motif | Prediction | Source | DNA binding | Support | Logo | Actions |
|---|---|---|---|---|---|---|
| M09455_2.00 | NN 70-40% | CisBP | GCACGTACCC | 53.3% identity | Open · Scan |
ModCRE0
No generated PWM in this category.
Model-supported DNA-binding regions
Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.
1
769 aa
46-292
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
Region 46-2921 model
| Actions | ||||
|---|---|---|---|---|
| Predicted = Low | TFS_B4E2K5:46:292_4zpr_B_1 | 4zpr | 46-292 | View model · PDB |
View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.
Domains
Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.
| Residues | PFAM | Domain | Used by prediction region? |
|---|---|---|---|
| 1-49 | PF23171 | Hypoxia-inducible factor 1-alpha bHLH domain | overlaps 46-292 |
| 197-282 | PF08447 | PAS fold | overlaps 46-292 |
| 498-523 | PF11413 | Hypoxia-inducible factor-1 | No overlap with loaded model regions |
| 733-768 | PF08778 | HIF-1 alpha C terminal transactivation domain | No overlap with loaded model regions |